A kind of sugar-free Fengreganmao granule and preparation method thereof

Abstract

The invention relates to sugar-free anemopyretic cold granules and a preparation method thereof. The granules mainly comprise major materials and auxiliary materials, wherein the major materials comprise isatis root, weeping forsythia, mint, schizonepeta spike, mulberry leaf, rehmannia root, great burdock achene, chrysanthemum, bitter apricot seed, mulberry twig and medicated leaven; and the auxiliary materials mainly comprise stevioside, aspartame, sodium starch glycolate and an appropriate amount of malto dextrin. The preparation method comprises the following steps of: extracting volatile oil from mint and schizonepeta spike for later use; dosing decoction dregs left after the extraction of volatile oil and other major materials in a specified sequence; decocting three times; filtering; concentrating the filtrate at reduced pressure to obtain clear paste of which the relative density is 1.05-1.15 (60 DEG C); performing spray drying to obtain extract powder; adding the screened auxiliary materials into the extract powder; putting the mixture into a dry type granulator to obtain granules of 10-30 meshes; spraying the extracted volatile oil; mixing uniformly; and packaging. The granules prepared with the method have the advantages of no containing of sugar cane, small using quantities of auxiliary materials, greatly lowered dosing amount compared with the original granules, low production cost and high content of arctiin serving as an active ingredient after process improvement.

Description

technical field [0001] The invention relates to a Ganmao granule and a preparation method thereof, in particular to a sugar-free Fengreganmao granule and a preparation method thereof, belonging to the technical field of traditional Chinese medicine granules. Background technique [0002] The prescription of Fengreganmao Granules comes from page 44 of the first volume of Chinese Drug Standards. Composition of medicinal flavors, functions and indications are: dispelling wind and clearing heat, relieving sore throat and detoxification. For wind-heat cold, fever, sweating, stuffy nose, headache, sore throat, cough, phlegm. [0003] There are more than 50 companies in the country producing Fengremao granules. The main manufacturers are Guangdong Yifang Pharmaceutical, Yunnan Baiyao, Sanjiu Pharmaceutical, Ningxia Qiyuan Pharmaceutical, Wuhan Jianmin Pharmaceutical, etc. The annual sales of such products of each enterprise It ranges from a few million yuan to tens of millions of...

AI Technical Summary

Problems solved by technology

[0004] At present, a large amount of sucrose powder and dextrin are added according to the prescription in the market. According to the prescription and production method stipulated in this standard, each bag of granules is 10g, which contains about 7g of excipients in total, and sucrose accounts for more than 5g. Fengreganmao granules are commonly used Drugs, for diabetic patients, taking a lot of sugar will greatly increase the burden on the islets and aggravate the disease; in addition, in recent years, more and more obese patients, because sugar is easily converted into fat after metabolism, therefore, obesity Therefore, for some people, Fengremao granules containing a large amount of sucrose are not suitable. In order to solve the problem that Fengremao granules contain a large amount of sucrose and affect their application, Technicians conducted research on the formulation and process of sugar-free Fengreganmao granules

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