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A kind of traditional Chinese medicine preparation for treating heart palpitations

A technology for traditional Chinese medicine preparations and raw materials, which is applied in the field of traditional Chinese medicine preparations for the treatment of palpitations, can solve the problems of few drugs, limited application scope, clinical tolerance, poor compliance, etc., and achieves the effects of good curative effect and low production cost.

Active Publication Date: 2011-12-21
THE AFFILIATED HOSPITAL OF SHANDONG UNIV OF TCM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the clinical diagnosis of this disease is relatively easy in modern medicine, its treatment and prognosis evaluation are more difficult.
With the advancement of medicine, although the current interventional therapy may completely ablate the ectopic pacemaker, it is not suitable for most patients because the age of the patients tends to age, and the risk and treatment cost increase. Therefore, the current antiarrhythmic drugs are still is the main line of treatment
However, due to the arrhythmogenic effect of antiarrhythmic western medicine itself and the potential danger of inhibiting the normal physiological activity of the heart, its clinical tolerance and compliance are poor; in addition, its electrophysiological effect is single, so its application range is limited limit
[0004] At present, there is a lack of drugs with good curative effect on heart palpitations in the prior art, and there are few similar drugs in the domestic pharmaceutical market

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024] Embodiment 1 prepares the Chinese medicine preparation (granule) for the treatment of palpitation

[0025] The formula is: Coptidis 12 grams, Sophora flavescens 12 grams, Angelica 15 grams, Rehmannia glutinosa 16 grams, Suanzaoren 38 grams, Baiziren 22 grams (one dose).

[0026] The preparation method is:

[0027] (1) Take Coptis chinensis, Sophora flavescens, Rehmannia glutinosa, Angelica sinensis, Jujube seed, and Baizi kernel, add water to decoct, add water 10 times the quality of medicinal materials, extract twice, each time for 2 hours;

[0028] (2) Combine the above decoctions, filter, and concentrate the filtrate to an extract with a relative density of 1.20 (60°C);

[0029] (3) Adding 95% ethanol (volume mass fraction) to the alcoholic extract is 60% (volume mass fraction) to the extract, and let it stand for 24 hours; get the supernatant, filter, reclaim ethanol, and concentrate to a relative density of 1.30 (60°C) thick paste.

[0030] (4) The concentrated ...

Embodiment 2

[0031] Embodiment 2 prepares the Chinese medicine preparation (capsule) for the treatment of palpitation

[0032] The formula is: 10 grams of coptis, 14 grams of flavescens, 14 grams of angelica, 17 grams of rehmannia, 35 grams of wild jujube kernels, and 25 grams of Baiziren (one dose).

[0033] The preparation method is:

[0034] (1) Take Coptis chinensis, Sophora flavescens, Rehmannia glutinosa, Angelica sinensis, Jujube seed, and Baizi kernel, add water to decoct, add water 10 times the quality of medicinal materials, extract twice, each time for 2 hours;

[0035] (2) Combine the above decoctions, filter, and concentrate the filtrate to an extract with a relative density of 1.20 (60°C);

[0036] (3) Adding 95% ethanol (volume mass fraction) to the alcoholic extract is 60% (volume mass fraction) to the extract, and let it stand for 24 hours; get the supernatant, filter, reclaim ethanol, and concentrate to a relative density of 1.30 (60°C) thick paste.

[0037] (4) Dry th...

Embodiment 3

[0038] Embodiment 3 prepares the Chinese medicine preparation (tablet) for the treatment of palpitation

[0039] The formula is: Coptidis 13 grams, Sophora flavescens 11 grams, Angelica 16 grams, Rehmannia glutinosa 16 grams, Suanzaoren 40 grams, Baiziren 20 grams.

[0040] The preparation method is the same as that in Example 1, but finally, it is crushed through an 80-mesh sieve to obtain the drug powder, and conventional auxiliary materials are added to make tablets.

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PUM

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Abstract

The invention discloses a Chinese medicinal preparation for treating palpitation. The Chinese medicinal preparation is prepared from the following Chinese herbal medicines in part by weight: 9 to 15 parts of golden thread, 9 to 15 parts of lightyellow sophora root, 12 to 18 parts of Chinese angelica, 15 to 18 parts of rehmannia root, 30 to 45 parts of spina date seed and 15 to 30 parts of platycladi seed. During preparation, the Chinese medicinal preparation can be prepared into various formulations which are used clinically, such as tablets, granules, capsules, pills and the like. In the Chinese medicinal preparation, the rehmannia root and the Chinese angelica are used for nourishing yin and blood to address root cause, the golden thread and the lightyellow sophora root are used for clearing heat and purging intense heat, and the spina date seed and the platycladi seed are used for soothing nerves and calming palpitation to address symptoms; and the Chinese herbal medicines are rigorous in compatibility, comprise monarch, minister, assistant and guide medicaments, are complementary to each other, have the effects of nourishing yin and blood, purging intense heat, soothing nerves, nourishing heart-yin, clearing away heart-fire, calming mind and the like, and are mainly used for treating palpitation, inquietude and rapid pulse due to deficiency of the heart-yin and excessive fire in heart. During treatment, the Chinese medicinal preparation is taken orally, one dose is taken every day, 6 to 7 days is one treatment course, and the palpitation can be cured for three or four treatment courses.

Description

technical field [0001] The invention provides a traditional Chinese medicine preparation for treating heart palpitations and a preparation method thereof. Background technique [0002] Palpitation refers to a class of symptoms in which the patient feels the palpitation in the heart, or even can't do it independently. When it occurs, the patient feels that the heartbeat is fast and strong, accompanied by discomfort in the precordial area. It belongs to the category of "palpitations" and "convulsions" in the motherland's medicine. This disease can be seen in a variety of disease processes, often coexisting with insomnia, forgetfulness, dizziness, tinnitus, etc. Any abnormal heart beat frequency and rhythm caused by various reasons can lead to palpitations. [0003] Motherland medicine has a long history and rich experience in the research of this disease. It belongs to the category of "palpitations" and "palpitations". , fire, and stasis disturb the heart, and the mind is r...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61P9/06
Inventor 杨传华陆峰孙洪胜傅春升彭伟
Owner THE AFFILIATED HOSPITAL OF SHANDONG UNIV OF TCM
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