Application of Tibetan medicinal composition to preparation of medicament for preventing and treating osteoporosis
A technology of osteoporosis and composition, which is applied in the field of medicine, can solve the problems such as the use of Wugensan osteoporosis medicine has not been found, and achieve the effect of prevention and treatment of osteoporosis
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Embodiment 1
[0044] Preparation of hard capsules
[0045] 100 parts of Tibetan celery, 100 parts of Himalayan mirabilis, 100 parts of Tribulus terrestris, 100 parts of sealwort, 100 parts of asparagus;
[0046] Coarsely pulverize the above-mentioned raw materials in specific weight parts into medicinal powders, decoct them in water with 10, 8, and 8 times the total weight of the medicinal powders, and extract them for 3 times. , Combine the extracts, filter the extracts, add ethanol to the filtered extracts to make the alcohol content 50%, leave it overnight, filter to remove the precipitate, and concentrate the filtrate to a relative density at 65°C It is a concentrated solution of 1.25-1.35. After spray drying, add appropriate amount of starch, sodium carboxymethyl cellulose and sodium carboxymethyl starch to the spray powder to granulate, fill and pack to obtain hard capsules.
Embodiment 2
[0048] Preparation of granules
[0049] 100 parts of Tibetan celery, 50 parts of Himalayan mirabilis, 150 parts of Tribulus terrestris, 100 parts of sealwort, 150 parts of asparagus;
[0050] Coarsely pulverize the above-mentioned specific weight portion of the crude drug into a medicinal powder, decoct it with water 10 times the total weight of the medicinal powder each time, and extract it for 3 times, each decocting time is 1 hour, collect and combine the extracts , filter the extract, concentrate the filtrate into a concentrated solution with a relative density of 1.05-1.15 at a temperature of 70°C, and after spray drying, add an appropriate amount of dextrin and aspartame to the spray powder to granulate, Made into granules (sugar-free).
Embodiment 3
[0052] Tablet preparation
[0053] 50 parts of Tibetan celery, 150 parts of Himalayan mirabilis, 100 parts of Tribulus terrestris, 50 parts of sealwort, 50 parts of asparagus;
[0054] Coarsely pulverize the above-mentioned crude drug in specific parts by weight into medicinal powder, reflux extract with 30wt% ethanol for 4 times, each time the amount of ethanol is 5 times of the total weight of the medicinal powder, and extract for 0.5 hour each time, collect and combine the extracts, and extract the extracts Filter, pass the filtrate into the HPD-300 macroporous adsorption resin with a flow rate of 0.1-10 times the bed volume / hour for adsorption, washing and analysis, wash with water first, then wash with 10wt% ethanol, and finally analyze with 60wt% ethanol, Collect the ethanol liquid, recover the ethanol and concentrate it into a concentrated solution with a relative density of 1.05-1.15. After freeze-drying, grind the dry powder of the obtained extract into a fine powde...
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