The invention relates to the technical field of food, in particular to a Chinese wolfberry-potato nutrition vermicelli which is made from potato with rich vitamin C, beneficial dietary fiber and high-quality potassium sources, Chinese wolfberry powder, seabuckthorn powder and rhodiola root powder which are special local products in Qinghai-Tibetan Plateau, and an additive. The raw materials of the Chinese wolfberry-potato nutrition vermicelli comprise 10-60% of potato starch, 10-40% of Chinese wolfberry condensed juice, 10-20% of bean starch, 4-10% of the seabuckthorn powder, 4-10% of the rhodiola root powder, 1-5% of an isolating agent and proper amount of water; the Chinese wolfberry-potato nutrition vermicelli is convenient for being eaten and has rich nutrition, and has a plurality of functions of nourishing liver and kidney, nourishing yin and strengthening yang, tonifying qi and replenishing the blood, resisting anoxia, fatigue, cold, aging, microwave radiation, etc. The Chinese wolfberry-potato nutrition vermicelli has the healthcare and medical efficacies on postponing senility after long term use, and is especially suitable for the sub-health population of the middle-aged and the elderly to prevent diseases, malnutrition and vulnerability to fatigue and weakness.