17results about How to "Good probiotic properties" patented technology

The invention belongs to the technical field of microorganisms, and particularly relates to probiotic characteristics of lactic acid bacteria and a relieving effect of a metagen of the lactic acid bacteria on pulmonary fibrosis. The invention discloses pediococcus pentosaceus ZFML001, and the preservation number of the pediococcus pentosaceus ZFML001 is CCTCC (China Center for Type Culture Collection) NO: M 2024601. The invention also provides a metagen prepared from the pediococcus pentosaceus ZFML001 at the same time, and provides an application of the metagen in preparation of a medicine for relieving or assisting in treatment of pulmonary fibrosis. The invention further provides the application of the metagen in preparation of a medicine for relieving or assisting in treatment of pulmonary fibrosis.

The invention provides a plant lactobacillus pentosus for promoting cellular immunoregulation as well as application and a product thereof, and belongs to the field of microorganisms. The preservation number of the provided lactobacillus pentosus is CGMCC (China General Microbiological Culture Collection Center) No.32858, and the lactobacillus pentosus is preserved in the China General Microbiological Culture Collection Center on November 29, 2024. The strain provided by the invention can promote macrophages to secrete TNF-alpha, IL-10 and IL-1beta in a normal state and down-regulate the secretion of NO, and meanwhile, the thermally inactivated strain also has the effect of promoting the macrophages to secrete TNF-alpha, and can further intervene in the secretion of TNF-alpha, IL-10 and IL-1beta in a macrophage inflammation state; in a Caco-2 cell-macrophage co-culture system and a mouse primary epithelial cell-splenic lymphocyte co-culture system, a promotion effect is also shown.

The invention relates to the field of microorganisms, in particular to cat milk-derived pediococcus acidilactici and application thereof. The cat milk source pediococcus acidilactici provided by the invention is preserved in the China General Microbiological Culture Collection Center on July 1, 2024, the preservation address is Institute of Microbiology, Chinese Academy of Sciences, No. 3, Beichen West Road, Chaoyang District, Beijing, China, and the preservation number is CGMCC NO.31006. The cat milk-derived pediococcus acidilactici provided by the invention is obtained by screening from healthy cat milk, has relatively strong acid resistance and bile salt resistance, is extremely strong in intestinal tract adhesion capacity, has a good inhibition effect on common pathogenic bacteria, is sensitive to various antibiotics, has good probiotic potential, and can be used for preparing a feed additive for the cat milk-derived pediococcus acidilactici. The invention provides a new candidate strain for pet food, health care and treatment products or probiotic preparations, and has wide application prospects in the aspects of preparation of pet food, health care products, medicines and the like.

The invention belongs to the technical field of drug delivery and food medicine, and particularly relates to resistant starch of intestinal targeted slow-release polyphenol and a preparation method and application of the resistant starch of the intestinal targeted slow-release polyphenol. Performing annealing recrystallization on the heat-dispersed high-amylose corn starch in an ethanol solution to obtain single-spiral structure resistant corn starch; and self-assembling the resistant corn starch with the single-spiral structure and the quinoa polyphenol extract in an alcohol-water system to obtain the intestinal targeted slow-release polyphenol resistant starch. According to the resistant starch of the intestinal targeted slow-release polyphenol prepared by the method disclosed by the invention, the specific starch spiral structure can realize the intestinal targeted controlled release of the polyphenol contained in the intestinal targeted slow-release polyphenol, so that the loss of phenolic compounds in the gastrointestinal digestion process is reduced, and the accurate and continuous release of the polyphenol compounds in the intestinal digestion stage is realized; the residence time of the polyphenol in the intestinal tract is prolonged, so that the bioavailability of the polyphenol is improved.

The invention relates to the field of food preparation, in particular to a konjak vegetarian meat processing technology which comprises the following steps: cleaning and grinding konjak, then pouring the ground konjak pulp into an ethanol-citric acid solution, soaking for 3-5 hours, performing microwave treatment in the soaking process, and then centrifuging, washing and drying to obtain pretreated konjak powder; adding water into the pretreated konjaku flour, uniformly mixing, and adding a compound enzyme for enzymolysis to obtain enzymolysis konjaku; adding soybean protein powder, vital gluten, fermented starch, mulberry leaf powder and a flavoring agent into the enzymolysis konjak, and uniformly stirring and mixing to obtain a mixture; heating the mixture, and continuously stirring in the heating process until the mixture is formed to obtain a vegetarian meat semi-finished product; and cutting the vegetarian meat semi-finished product into strips, and frying to obtain the konjac vegetarian meat. In the processing process of the konjak vegetarian meat, the probiotic effect of the konjak glucomannan in intestinal tracts is effectively improved, and the health value of the konjak vegetarian meat is improved.

The invention discloses application of breast milk-derived lactobacillus gasseri in reducing weight, reducing blood fat, preventing and treating type 2 diabetes mellitus, relieving intestinal leakage and inhibiting intestinal pathogens, and belongs to the technical field of microorganisms and the technical field of medicines. The invention provides a new application of lactobacillus gasseri in reducing weight, reducing blood fat, preventing and treating type 2 diabetes, relieving intestinal leakage and inhibiting intestinal pathogens. The traditional Chinese medicine composition can effectively prevent weight gain, body fat rate increase, low-density lipoprotein cholesterol and triglyceride increase of mice caused by high-fat diet, inhibit postprandial blood sugar and insulin resistance index increase, inhibit intestinal mucosa damage and growth of intestinal pathogenic bacteria, and effectively improve chronic diseases of mice with high-fat diet. Therefore, the lactobacillus gasseri FN136 has a huge application prospect in preparation of products for reducing weight, reducing blood fat, preventing and treating type 2 diabetes mellitus, relieving intestinal leakage and inhibiting intestinal pathogens.

The invention discloses a compound microecological preparation, fermentation liquor and application of the compound microecological preparation in laying hen production. The compound micro-ecological preparation is prepared from clostridium butyricum NIP1021, bacillus cereus 2022B1, bacillus licheniformis 2022B2 and enterococcus faecium 2022B6. The fermentation liquor of the compound micro-ecological preparation can promote the growth performance levels of the Haillan grey laying hens, such as the final weight and the like; the development of thymus and bursa of Fabricius immune organs of laying hens can be promoted; the content of serum immune globulin IgG and serum-related immune cell factors IL-1beta, IL-6 and TNF-alpha of laying hens is remarkably increased, so that the serum nonspecific immune level of animal bodies is improved; according to the method, the intestinal villus area of the laying hens is increased, the nutrient absorption capacity of the laying hens is improved, cecum flora diversity and species abundance are increased, dominant flora categories are thick-wall flora and bacteroides to regulate intestinal flora balance, and the method has positive significance in maintaining intestinal health.

This invention discloses a strain of Zygosaccharomyces rouxii, DL-WSY01, and its applications, belonging to the field of food biotechnology. This invention provides a strain of Zygosaccharomyces rouxii, DL-WSY01, with accession number CGMCC No. 25335. The DL-WSY01 strain exhibits rapid growth and excellent fermentation performance; it is also tolerant to the gastrointestinal environment, demonstrating good probiotic properties; it is sensitive to common fungal antibiotics, non-hemolytic, and exhibits good safety; it effectively tolerates high salt, acid, and ethanol; it possesses antioxidant properties; it can produce high levels of ethanol; it can also produce high levels of flavor compounds and has biogenic amine degradation capabilities. Therefore, this strain, as a starter culture, can ensure the safety and flavor quality of fermented foods such as fermented soybean paste and soybean paste, and significantly improve the nutritional value of fermented foods.

The application relates to the field of food preparation, in particular to konjac meat processing technology, comprising the following steps: konjac is cleaned and ground, then the ground konjac paddle is poured into an ethanol-citric acid solution and soaked for 3-5h, during the soaking process, microwave treatment is carried out, then centrifugation, washing, drying obtains pre-treated konjac flour; water is added to the pre-treated konjac flour, and complex enzyme is added for enzymolysis after mixing, and enzymolysis konjac is obtained; soy protein powder, gluten powder, fermented starch, mulberry leaf powder, flavoring agent are added to the enzymolysis konjac, stirring and mixing are uniform, and a mixture is obtained; the mixture is heated, and continuously stirred to molding during heating to obtain a semi-finished vegetarian meat; the semi-finished vegetarian meat is cut into strips, and konjac meat is obtained after frying. The present invention is in the processing process of konjac meat, effectively improves the prebiotic effect of konjac glucomannan in the intestinal tract, and improves the health value of konjac meat.

The invention discloses a strain of acetobacter grifanii JK-23 and application thereof in antioxidation and anti-inflammation, the strain is preserved in China Center for Type Culture Collection on July 3, 2024, and the preservation number is CCTCC NO: M 20241457. The strain has significant probiotic characteristics, has good antioxidant and anti-inflammatory capabilities, and can significantly relieve H2O2-induced IPEC-J2 cell oxidative damage. The traditional Chinese medicine composition can be used for remarkably relieving the reduction of colon length caused by DSS, colitis sexual infiltration, the reduction of antioxidant indexes CAT and SOD in serum, the abnormal increase of MDA and MPO in the serum and the abnormal increase of the expression quantity of pro-inflammatory TNF-alpha, IL-10, IL-6 and IL-12 in the serum and colon; the strain can be used as a microbial drug or product with a good industrial prospect for treating or relieving cell oxidative damage and colitis, and has potential clinical application value.

The present application belongs to the field of microbial application and feed processing technology, and discloses a bacillus subtilis, named bacillus subtilis YT1, which is preserved in China Center for Type Culture Collection, located at Wuhan University, No. 299, Bayi Road, Wuchang District, Wuhan City, Hubei Province, with a preservation number of CCTCC NO: M 20242767 and a preservation date of December 10, 2024. The present application also discloses a microbial preparation and the application of the bacillus subtilis or the microbial preparation in the processing of silage. The present application first simultaneously possesses high efficient lignocellulose degradation ability, excellent fermentation promotion characteristics, significant antioxidant activity and good probiotic characteristics in a strain of bacillus subtilis. This characteristic enables a single bacterial agent to achieve multiple goals such as fiber degradation, fermentation promotion, oxidation protection, which traditionally requires multiple compounded bacterial agents, and fundamentally overcomes the problems of poor compatibility between strains, unstable synergistic effect and high application cost of existing compounded additives.

This invention discloses a strain of Candida smoothiae ( Candida metapsilosis This invention relates to DL-GZRT3 and its applications, belonging to the fields of microbial biotechnology or food biotechnology. The DL-GZRT3 strain of this invention grows well under conditions of 15% NaCl concentration, pH 2, and 6% ethanol concentration. It is tolerant of high salt, acid, and ethanol; it can tolerate the gastrointestinal environment, exhibiting excellent probiotic properties and good safety. The DL-GZRT3 strain possesses good antioxidant properties, with a DPPH scavenging rate of 82.93% and an ABTS scavenging rate of 66.95%, and can produce high concentrations of esters and alcohols during fermentation. Therefore, *Candida glabrata* strain DL-GZRT3 can ensure the safety and flavor quality of fermented foods, shorten the fermentation cycle, and significantly improve the nutritional value of fermented foods.

The invention relates to the field of microorganisms, in particular to cat milk-derived pediococcus pentosaceus and application thereof. The cat milk-derived pediococcus pentosaceus provided by the invention is preserved in China General Microbiological Culture Collection Center (CGMCC) on June 19, 2024, the preservation address is Institute of Microbiology, Chinese Academy of Sciences, No. 3, No.1 yard, West Beichen Road, Chaoyang District, Beijing, China, and the preservation number is CGMCC NO.31004. The cat milk-derived pediococcus pentosaceus provided by the invention is obtained by screening from healthy cat milk, is extremely high in adhesive capacity, has good probiotic potential, has an inhibition effect on common pathogenic bacteria, is good in antibacterial performance, is sensitive to various antibiotics, has relatively high acid resistance and bile salt resistance, and can be used for preparing the cat milk-derived pediococcus pentosaceus. The invention provides a new candidate strain for pet food, health care and treatment products or probiotic preparations, and has wide application prospects in the aspects of preparation of pet food, health care products, medicines and the like.

The present invention relates to the field of microbial technology, and in particular to a strain of Pediococcus acidilactici, a composition containing the same, and uses thereof. The Pediococcus acidilactici is Pediococcus acidilactici H47, with a deposit number of CCTCC NO: M20232100, and is deposited in the China Center for Type Culture Collection. The composition comprises at least one of Pediococcus acidilactici and a culture of the strain. The advantages of the present invention are as follows: (1) efficient degradation of mycotoxins. (2) strong growth ability, acid and bile resistance. (3) safety, and good probiotic properties.

The present invention belongs to the field of bioengineering technology, and provides a strain of Lactococcus garvei FUA009 isolated from human intestinal tract, and a method for producing urolithin A using the strain. The method is easy to operate, has high yield, and is suitable for mass production of urolithin A. The Lactococcus garvei FUA009 provided by the present invention has high safety, good probiotic properties, and has the potential to become a new type of probiotic.

The invention discloses lactic acid bacteria with an effect of reducing uric acid as well as a screening method and application of the lactic acid bacteria, and belongs to the field of microorganisms, the classification name of the lactic acid bacteria is Limosilicilla fermentum FOSU-YHD19, the lactic acid bacteria are preserved in Guangdong Microbial Culture Collection Center, the preservation date is March 6, 2024, and the preservation number is GDMCC NO.64389. The invention further discloses a preparation method of the lactic acid bacteria with the effect of reducing uric acid. The screened lactic acid bacteria have a remarkable effect of reducing the uric acid value, the obtained lactic acid bacteria have excellent safety and prebiotics, a new microbial strain resource is provided for treating hyperuricemia, and the lactic acid bacteria have excellent application value when being applied to preparation of products for reducing the uric acid value. The lactic acid bacteria are applied to the field of marine organism culture, purine metabolism in marine organism bodies can be promoted, and then the purine content of seafood products is effectively reduced. Besides, the lactic acid bacteria are added into the field of marine organism culture, so that pathogenic bacteria in marine organism bodies can be inhibited, the microbial environment can be adjusted, and marine products with relatively low purine can be obtained.

The invention discloses a compound microbial preparation for laying hen production, brown sugar fermentation liquor and application thereof. The compound microbial preparation is prepared from clostridium butyricum NIP1021, bacillus cereus 2022B1, bacillus licheniformis 2022B2, enterococcus faecium 2022B6 and paenibacillus polymyxa CP7, and the compound microbial preparation can ensure normal fermentation in a low-pH environment during fermentation of brown sugar, so that infectious microbe pollution is avoided; the prepared compound microbial preparation fermentation liquor can promote the growth performance of laying hens, improve the intestinal flora balance of the laying hens, promote the intestinal health of the laying hens, improve the organism immunity of the laying hens and reduce the use of antibiotics.