28 results about "Stachyose hydrate" patented technology

The invention relates to the field of biotechnology and female health care, in particular to a stachyose composition for promoting micro-ecological regulation of lactobacillus and application of the stachyose composition, and the composition comprises stachyose and pharmaceutically acceptable auxiliary materials. The stachyose is used as prebiotics to selectively promote proliferation and colonization of the lactobacillus crispatus, the combination of 1%-5% of the stachyose and 0.1%-0.5% of the lactic acid can promote proliferation of the lactobacillus crispatus, the lactobacillus crispatus is one or more of the lactobacillus crispatus, the lactobacillus plantarum and the lactobacillus acidophilus, and the combination of 1%-5% of the stachyose and 0.1%-0.5% of the lactic acid can inhibit gardnerella and candida albicans. The stachyose composition disclosed by the invention is in the form of slow-release gel and bath foam; the composition can be used for treating or preventing bacterial vaginitis, colpitis mycotica and related symptoms, has the advantages of no antibiotics, no drug resistance, high safety and the like, and is suitable for the fields of vagina local nursing and micro-ecological regulation.

The invention provides flash-soluble direct-drinking fungus powder and a preparation method thereof. The flash-soluble direct-drinking bacterial powder comprises the following components in parts by weight: 65-75 parts of erythritol, 10-16 parts of stachyose, 2-5 parts of L-arabinose, 1-3 parts of mono-and diglycerides of fatty acids, 2-5 parts of resistant dextrin and 2-10 parts of probiotics or metabiotics. By adopting the stachyose and the L-arabinose in parts by weight, the sweetness of the flash-soluble direct-drinking fungus powder is effectively reduced; on the premise of being matched with other components, the oligosaccharide shows the performance completely different from that of conventional oligosaccharide, particularly erythritol, stachyose and L-arabinose can be fully dispersed under the action of mono-and diglycerides of fatty acids, so that the effect advantages of the oligosaccharide can be better played, and the flash-soluble direct-drinking fungus powder can keep the flash-soluble characteristic and can be used for preparing the instant instant fungus powder. The oral liquid is quick to melt in the oral cavity, easy to swallow, strong in impact feeling and cool feeling, weak in mouth choking degree and mouth stickiness, weak in granularity, and weak in oral cavity covering feeling and oral cavity drying feeling of whole residues after swallowing.

The present invention provides a probiotic active antibacterial tablet for preventing and treating female reproductive system infection and a preparation method thereof. The present invention is a probiotic active antibacterial tablet for preventing and treating female reproductive system infection, comprising the following raw materials in parts by weight: 1.8-2.5 parts of Lactobacillus reuteri, 1.0-1.2 parts of Lactobacillus rhamnosus, 1.2-1.7 parts of Lactobacillus crispatus, 0.5-0.8 parts of Lactobacillus gasseri, 1.0-1.5 parts of stachyose, 0.8-1.2 parts of inulin, and 2.5-3 parts of plant extract, wherein the plant extract is prepared from the following raw materials: Bletilla striata, Chinese tallow tree leaf, Gentiana scabra, and grapefruit seed. The probiotic active antibacterial tablet prepared by the present invention has a significant inhibitory effect on IGFBP7 protein, can effectively prevent and treat female reproductive system infection, and has good tolerance and safety.

The invention belongs to the technical field of nutritious food, discloses a soluble fiber solid beverage and a preparation method thereof, and solves the problems of single component, lack of functional synergy and insufficient universality of the existing soluble fiber solid beverage. The soluble fiber solid beverage is prepared from the following components in parts by weight: 1 to 2 parts of alginate oligosaccharide, 25 to 40 parts of resistant dextrin, 20 to 30 parts of inulin, 15 to 25 parts of polydextrose, 10 to 20 parts of fructo-oligosaccharide, 3 to 5 parts of stachyose and 0.1 to 0.3 part of stevioside. The total soluble fiber content can reach 88.5%, the dissolution time is only 2.3 s, the particle size of undissolved particles is smaller than or equal to 5 microns, the abdominal distension occurrence rate is 6.0%, the gas production rate is 10.0%, and the low-sugar-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low-fat-content low

The invention provides a method for evaluating prebiotics and a compound combination thereof based on an in-vitro simulation fermentation model-co-culture cell model, and the method comprises the following steps: preparation of fecal bacteria suspension, preparation of an in-vitro fermentation culture medium, in-vitro fermentation culture and index determination of single prebiotics, and in-vitro fermentation culture and index determination of composite prebiotics. The method comprises the following steps: establishing a cell co-culture model, carrying out co-culture on composite prebiotics and cells, determining indexes, and determining optimal monomer prebiotics and composite prebiotics. By means of the method, the optimal prebiotic compound composition composed of the tea polyphenol, the fructo-oligosaccharide and the stachyose is obtained through screening for the first time, the antioxidant activity of the compound prebiotics and the synergistic anti-inflammatory effect of the short-chain fatty acid are proved, and the compound prebiotics are applied to preparation of the soft sweets.

A solid cannabinoid composition comprising: (i) 0.3 to 10 wt.% of one or more cannabinoids; (ii) from 4 to 69 wt.% of one or more non-ionic surfactants having an HLB value of from 10 to 25; and (iii) at least 20 wt.% of one or more carbohydrates selected from the group consisting of mannitol, sucrose, trehalose and stachyose; (iv) 0 to 5 wt.% of water; wherein the combination of the one or more non-ionic surfactants and the one or more carbohydrates comprises at least 70 wt.% of the composition. A sterile aqueous liquid for medical treatment, the liquid comprising: (a) 0.1 to 10 mg / mL of one or more cannabinoids; (b) one or more nonionic surfactants having an HLB value of from 10 to 25; (c) one or more carbohydrates selected from the group consisting of mannitol, sucrose, trehalose and stachyose; and (d) at least 85 wt.% water; wherein the one or more nonionic surfactants and the one or more cannabinoids are present in the sterile aqueous liquid in a weight ratio of 3: 1 to 30: 1, and wherein the one or more carbohydrates and the one or more cannabinoids are present in the sterile aqueous liquid in a weight ratio of 3: 1 to 300: 1.

The invention belongs to the technical field of microorganisms, and particularly discloses a composition with anti-aging and anti-saccharification functions and application of the composition. The composition is prepared from the following components: lactobacillus paracasei BL-22 and stachyose, wherein the lactobacillus paracasei BL-22 is prepared from lactobacillus paracasei BL-22 and stachyose; the preservation number of the lactobacillus paracasei BL-22 is CGMCC (China General Microbiological Culture Collection Center) NO. 33475. Through animal experiments and research on interaction of the two substances, the invention reveals that the lactobacillus paracasei BL-22 and the stachyose have a synergistic effect mechanism for the first time, and confirms that the lactobacillus paracasei BL-22 and the stachyose are combined to generate a remarkable synergistic effect in the aspects of relieving aging and skin saccharification. The invention provides a safe and convenient new scheme for solving the problems of skin aging and saccharification, and also provides a new research direction and technical support for development of aging health related products.

The present application relates to a kind of skin care composition and its application for quickly relieving sensitive skin hot red, enhancing skin tolerance, belong to the field of cosmetics.The raw materials of the skin care composition include schisandra chinensis extract, stachyose, Cynara scolymus leaf extract, red clover flower extract and citrus fruit extract five kinds of active ingredients, through the cross regulation of multiple target signal pathways, the complementary synergies of different action links and the overall coordination of metabolic network, form the synergistic amplification effect of "heat elimination and detoxification, slow down hot feeling, converge pores, enhance skin immunity".

The invention discloses an anti-aging, anti-wrinkle and anti-tumor Chinese yam polysaccharide composition and a preparation method thereof. The composition comprises the following components in parts by mass: 30-80 parts of Chinese yam polysaccharide, 10-50 parts of stachyose, 5-25 parts of pomegranate seed extract, 5-20 parts of grape seed extract, 3-15 parts of blueberry extract, 2-12 parts of tea polyphenol, 1-10 parts of sea cucumber peptide and 1-10 parts of soybean peptide (with the molecular weight of 300-1000Da). Preferably, 0.5-5 parts of resveratrol (the purity is greater than or equal to 98%) and 3-20 parts of acerola cherry powder (VC is greater than or equal to 15%) are added. The preparation method comprises the following steps: dissolving polysaccharides and saccharides, adding the extract, homogenizing, adjusting the pH value to 6.0-7.0, carrying out enzymolysis by using compound protease at 35-40 DEG C, and finally carrying out spray drying. Experiments show that the composition has a synergistic effect in the aspects of resisting saccharification (the highest inhibition rate reaches 78.5%), resisting oxidation (the DPPH clearance rate is 91.3%), increasing the content of hydroxyproline in skin (+ 74.1%), inhibiting tumor cell proliferation (62.5%) and improving ultraviolet wrinkles (the score is reduced by 61%).

The present application provides a nutrient composition including: stachydrine, lactobacillus plantarum, walnut peptide, desert cistanche, casein hydrolysate, and two or more of theanine. The present inventors found that the above nutrient composition has a brain health function in the direction of anxiolytic, antioxidant, neuroprotective, and memory improvement.

The application provides an allergy-improving probiotic composition, and belongs to the field of microbial preparations.The probiotic composition comprises Bacillus coagulans powder, Bacillus coagulans postbiotic, fructooligosaccharide, lactitol, pin cherry powder and stachyose.The application optimizes the application form of Bacillus coagulans, and further compounding other raw materials to prepare a composition which can effectively relieve allergy, and as a whole, has a significant effect on an animal model.

The invention belongs to the technical field of agricultural biology, and particularly relates to application of a CsSTS gene in resistance of piercing-sucking pests of cucumbers and a breeding method of pest-resistant varieties. The invention finds that the cucumber stachyose synthase gene CsSTS is a key gene for regulating and controlling the resistance of cucumbers to piercing-sucking pests such as aphis gossypii glover and bemisia tabaci. Aphis gossypii infection can significantly inhibit CsSTS gene expression of cucumbers, so that stachyose adverse to pests in a sieve tube solution is reduced, and sucrose preferred by the pests is increased. The CsSTS overexpression transgenic cucumber strain is created through genetic manipulation, CsSTS of the CsSTS overexpression transgenic cucumber strain is continuously and highly expressed, a screen tube liquid maintains a high stachyose level and is not affected by insect pests, and the strain shows strong resistance close to the immune level to aphis gossypii glover and also shows remarkable resistance to bemisia tabaci.

The invention relates to a soothing and repairing complex suitable for sensitive skin and a preparation method and application thereof, and belongs to the technical field of cosmetics. The soothing and repairing complex provided by the invention is prepared by coating the surface of microalgae extracellular vesicles with stachyose, astragalus polysaccharide and galactoglucan, the four raw material components cooperate with one another to play a role, and the soothing and repairing complex has the advantages that the soothing and repairing complex aims at a passive fragile state caused by skin immune system imbalance and low tolerance threshold; the saccharide-extracellular vesicle compound is used for simulating mild regulation on a skin immune system, so that the resistance of skin to external environment pressure is systematically improved on the premise of no stimulation risk, and the transformation from passive damage-repair to active defense-toughness is realized; the problems that sensitive skin is easy to stimulate and repeatedly red, the barrier function is weak and the like are fundamentally improved.

The application discloses a kind of oligosaccharide particles containing xylitol and a preparation method thereof, and relates to the technical field of oligosaccharide particle preparation, comprising the following raw materials: fructooligosaccharide powder, xylitol, modified resistant dextrin, modified stachyose, modified zein, anti-caking agent, deionized water, microcrystalline cellulose and binder forming agent.In the application, modified resistant dextrin is added, which forms a hydrophobic protective layer on the surface, effectively preventing the particle from absorbing moisture, sticking and caking, and prolonging the shelf life of the particle.The modified resistant dextrin can support the structure of the particle, reduce breakage, and ensure smooth cold water solubility, balancing the stability and solubility of the particle, and solving the pain points of pure oligosaccharide particles, such as moisture absorption and breakage.Modified stachyose is added, which can significantly reduce the intestinal irritation of prebiotics and avoid abdominal distension caused by rapid fermentation of ordinary stachyose.Meanwhile, the modified stachyose can synergistically act with fructooligosaccharide to strengthen the intestinal care effect and adapt to people with sensitive stomachs.

The invention relates to the related technical field of blueberry concentrated solutions, in particular to a blueberry concentrated solution and a preparation method thereof. 0.7% of polydextrose; 0.04% of potassium sorbate; the content of frozen blueberry fruits is 97.26%; the preparation method comprises the following steps: refrigerating and unfreezing the blueberries to ensure that the blueberries are in a state suitable for processing; performing pulping treatment to form uniform slurry; accurately weighing required auxiliary materials according to formula requirements of the blueberry concentrated juice; mixing the blueberry pulp with auxiliary materials, and then heating and concentrating; filling the concentrated blueberry juice into a clean bottle by using a filling machine; timely capping is carried out; performing water bath sterilization and cold water cooling; labeling the sterilized concentrated blueberry juice, and marking information such as production date and shelf life; boxing operation is carried out according to product specifications, and the safety of products in the transportation and storage process is ensured; the packaged blueberry concentrated juice finished product can be stored in a normal-temperature warehouse after passing self-inspection.

The invention discloses an oligosaccharide compound preparation capable of remarkably relieving irinotecan chemotherapy-induced intestinal injury, which is prepared by compounding alginic acid oligosaccharide, fructo-oligosaccharide and stachyose according to the mass ratio of (40-60): (20-30): (20-30), the alginic acid oligosaccharide, the fructo-oligosaccharide and the stachyose are high in safety and free of side effects, and can be applied to relieving irinotecan-induced chemotherapy-induced intestinal injury, and the three components cooperate to effectively promote proliferation of beneficial bacteria, so that the curative effect of irinotecan on the chemotherapy-induced intestinal injury is improved. The micro-ecological environment of the intestinal tract is improved from the source; intestinal inflammation caused by chemotherapy is rapidly inhibited, and release of inflammatory factors is reduced; the damaged intestinal mucosa is repaired, and the intestinal barrier function is enhanced; the technical effect of the irinotecan preparation is obviously better than that of a single oligosaccharide preparation or a pairwise compounded preparation, and the irinotecan preparation can effectively solve the clinical pain point of intestinal discomfort in the irinotecan chemotherapy process, so that smooth chemotherapy is guaranteed. Meanwhile, the preparation process disclosed by the invention does not need complex equipment, is simple and convenient to operate, has strong controllability, is suitable for industrial large-scale production, and has a good industrial prospect.

The invention discloses a stachyose composition and application thereof in treating diarrhea, and belongs to the technical field of biological medicine. The technical problem to be solved is that single prebiotics have limited effects in the aspects of promoting the generation of short-chain fatty acids (SCFAs), proliferating intestinal beneficial bacteria and repairing intestinal barrier functions. According to the technical scheme, the compound prebiotic composition is characterized in that stachyose (SS), xylooligosaccharide (XOS) and galactomannan (PHGG) are taken as core components, and the mass ratio of the stachyose (SS), the xylooligosaccharide (XOS) and the galactomannan (PHGG) is optimized, so that synergistic regulation and control on intestinal microecology are realized.

The application belongs to the field of medicine, and particularly relates to application of stachydrine and derivatives thereof to preparation of a medicine for preventing and / or treating pulmonary fibrosis. Researches of the application show that stachydrine can effectively prevent and / or treat pulmonary fibrosis.

The present invention discloses the use of stachyose in the preparation of a drug for treating castration-resistant prostate cancer, which belongs to the field of biomedicine. The present invention is the first to propose a new strategy for combining stachyose with androgen receptor antagonists to prepare a drug for treating CRPC, and conducts multifaceted and multi-stage validation research. The pharmaceutical composition of the present invention combining stachyose with androgen receptor can be used to treat castration-resistant prostate cancer, which can significantly improve the inhibitory effect of enzalutamide on castration-resistant prostate cancer, and the application of natural compounds to late-stage cancer is of great significance in clinical treatment.

A solid cannabinoid composition comprising: (i) 0.3 to 10% by weight of one or more cannabinoids; (ii) 4 to 69% by weight of one or more nonionic surfactants having an HLB value of 10 to 25; (iii) at least 20% by weight of one or more carbohydrates selected from mannitol, sucrose, trehalose, and stachyose; and (iv) 0 to 5% by weight of water, wherein the combination of one or more nonionic surfactants and one or more carbohydrates accounts for at least 70% by weight of the composition. A sterile aqueous solution for use in medical treatment, comprising: (a) 0.1 to 10 mg / mL of one or more cannabinoids; (b) one or more nonionic surfactants having an HLB value of 10 to 25; (c) one or more carbohydrates selected from mannitol, sucrose, trehalose, and stachyose; and (d) at least 85% by weight of water, wherein one or more nonionic surfactants and one or more cannabinoids are present in the sterile aqueous solution in a weight ratio of 3:1 to 30:1, and one or more carbohydrates and one or more cannabinoids are present in the sterile aqueous solution in a weight ratio of 3:1 to 300:1.

The invention relates to a sensitive skin red fading and relieving composition as well as a preparation method and application thereof. The sensitive skin red fading and relieving composition comprises the following components: stachyose, silk fibroin, glycosylglycerol, 4-tert-butyl cyclohexanol and a flaxseed extract. The weight ratio of the stachyose to the silk fibroin to the glycosylglycerol to the 4-tert-butyl cyclohexanol to the flaxseed extract is (0.5 to 8): (0.01 to 2): (0.01 to 1): (0.01 to 1): (0.01 to 1). The composition disclosed by the invention can achieve a good soothing effect through multi-target-point synergism, and has high efficiency and safety at the same time.

The application discloses a use of a pharmaceutical composition consisting of berberine hydrochloride and stachydrine in regulating intestinal flora of animals, and belongs to the technical field of medicines. The composition can selectively increase the number of a part of beneficial bacteria in the intestines of animals, and improve the structure of intestinal flora. In particular, the number of Akkermansia muciniphila in the intestines of animals can be significantly increased, and then the intestinal barrier function is improved through the regulating effect of intestinal flora, so that diseases such as obesity, diabetes, hyperlipidemia and the like are prevented or treated.

The invention discloses a TLC (Thin Layer Chromatography) detection method for quickly judging whether a non-medicinal part is doped into a selfheal medicinal material, and belongs to the technical field of pharmaceutical analysis. Research finds that obvious component difference exists in selfheal clusters, selfheal roots, selfheal stems and selfheal leaves, specifically, stachyose cannot be detected in the selfheal clusters, and stachyose can be clearly detected in the selfheal roots, the selfheal stems and the selfheal leaves. On the basis, the invention establishes a TLC method for judging whether non-medicinal parts are doped into the selfheal medicinal material or not. And comparing with the TLC map of the reference substance to judge whether the to-be-detected selfheal sample contains stachyose or not, thereby judging whether a non-medicinal part is doped into the selfheal medicinal material or not and distinguishing the medicinal part and the non-medicinal part of the selfheal. The TLC detection method provided by the invention is simple and rapid, is beneficial to guarantee the quality of selfheal and related products thereof, and guarantees the safety and reliability of clinical medication.

This invention discloses a high-pressure homogenization coupled with spray drying process for liposome preparation, belonging to the field of pharmaceutical preparation technology. The process includes the following steps: dissolving active ingredients, phospholipids, and cholesterol in an organic solvent and hydrating them to form a suspension; homogenizing the suspension under high pressure to obtain a homogenized solution; adding a glassy protective agent, chitosan, and thixotropic silica gel to the homogenized solution and mixing to obtain a composite solution; the glassy protective agent includes asiaticoside and stachyose; and subjecting the composite solution to gradient cooling spray drying to obtain liposomes. This invention, through high-pressure homogenization and the synergistic effect of the glassy protective agent composed of asiaticoside and stachyose, chitosan, and thixotropic silica gel, forms a multi-level synergistic protection during gradient cooling spray drying, significantly improving the rehydration integrity of liposomes, the long-term storage stability of active ingredients, and photostability.

The invention discloses an oil-control repairing composition for mild regulation of skin micro-ecology for sensitive skin and a preparation method and application thereof, and belongs to the technical field of cosmetics. The oil control and repair composition provided by the invention is prepared from the following components in parts by mass: 0.1 to 4.5 parts of a phellinus linteus extract, 0.1 to 4 parts of acetyl tetrapeptide-2, 0.01 to 1 part of a herba andrographitis leaf extract and 0.01 to 0.5 part of stachyose. The oil-control repairing composition provided by the invention can be matched with each other to effectively balance epidermal flora, increase the content of overall beneficial flora and reduce the content of overall harmful flora, and meanwhile, the oil-control repairing composition also has a good inhibition effect on 5 alpha-reductase and an anti-inflammatory effect; therefore, excellent short-term and long-term oil control, anti-inflammatory and repair effects can be realized.

The invention provides a method capable of increasing the content of astaxanthin in haematococcus pluvialis. The method comprises the following steps: culturing haematococcus pluvialis to haematococcus pluvialis cells in a later logarithmic growth stage and / or a plateau stage under a low-light condition; the method comprises the following steps: adding a stachyose solution into a haematococcus pluvialis culture medium to enable the final concentration of stachyose to be 1-10 mM, and then inducing astaxanthin accumulation in haematococcus pluvialis under a high-light condition of 150-400 mol / m < 2 > / s. Results show that 1 mM of sucrose has the highest economic benefit, the content of astaxanthin in haematococcus pluvialis can be increased by 37.3%, and the content of single-cell astaxanthin in haematococcus pluvialis can be increased by 35.1%.

This invention relates to a composition for repairing skin barrier damage in sensitive skin and its application, belonging to the field of cosmetic technology. The composition for repairing skin barrier damage of this invention comprises the following components: stachyose, 1,3-propanediol, lecithin, silymarin, and sennaol. The composition for repairing skin barrier damage of this invention has significant repairing and moisturizing effects and is suitable for sensitive skin.