Patents
Literature
1 results about "Complete protein" patented technology
Efficacy Topic
Property
Owner
Technical Advancement
Application Domain
Technology Topic
Technology Field Word
Patent Country/Region
Patent Type
Patent Status
Application Year
Inventor
A complete protein or whole protein is a food source of protein that contains an adequate proportion of each of the nine essential amino acids necessary in the human diet. Examples of single-source complete proteins are red meat, poultry, fish, eggs, milk, cheese, yogurt, soybeans and quinoa. The concept does not include whether or not the food source is high in total protein, or any other information about that food's nutritious value.
Multi-view structure prior negative sampling drug target interaction prediction method
This invention discloses a multi-view structural prior negative sampling method for predicting drug-target interactions, belonging to the field of bioinformatics. The method includes: acquiring a drug-target bipartite graph, corresponding drug features, and target protein features (as well as the corresponding drug SMILES sequences and the complete protein structure PDB file); applying a multi-view negative sampling strategy to the drug-target bipartite graph, corresponding drug features, and target protein features to generate drug-view negative sample sets, protein-view negative sample sets, and random-view negative sample sets, and then fusing them to obtain a negative sample set; using a heterogeneous graph convolutional network to perform feature learning on the drug-target bipartite graph and calculating the interaction prediction probability corresponding to each negative sample. This invention, through a multi-view structural prior-guided negative sampling mechanism, effectively utilizes the similarity knowledge between the chemical structure of the drug and the spatial structure of the target protein, reducing the risk of false negative samples and improving the quality of negative samples.
Owner:GUIZHOU NORMAL UNIVERSITY