The invention discloses a method for preparing the models of grinding-pressing-tearing-peeling wound on the
skin of small mammals, which comprises that: (1) after depilation and antisepsis are carried out on the
skin on the back of a rat, back
skin peeling
surgery is carried out for forming a rectangular
skin flap; (2) the prepared rectangular
skin flap on the back of the rat is placed on the skin
grinding-pressing-tearing-peeling shaping
machine,
uniform rotation and transversal movement of the muller are controlled electrically, when the rubber gear at the edge of the muller contacts the
skin flap,
grinding-pressing-tearing-peeling is produced, the pressure on the skin flap acted by the muller is controlled at 1.0-3.5kg, and the grinding-pressing-tearing-peeling wound of the rat is formed; (3) after seven days,
methylene blue is used to indicate the scope of survival and putrescence of the skin flap,
statistical analysis on the
survival rate of the skin flag is carried out; (4) the model of grinding-pressing-tearing-peeling wound is established, that is the grinding pressure is 2.0-2.5kg, the area of
necrotic tissue is moderate and accounts for 1 / 3 of the total area of the skin flap. The method of the invention has the advantages of accurate control on the produced grinding pressure, simple operation, invariable necrotic area of the skin flaps and good repetition, and the model of the invention is a better model for researching the grinding-pressing-tearing-peeling wound mechanism.