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Method and device for coating promoting bone growth

A coating, medical technology, applied in the field of medical implant coating, can solve the problems of equipment and time consumption

Inactive Publication Date: 2012-01-11
HERAEUS MEDICAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] However, all the electrochemical deposition methods customary to date have the disadvantage of being extensively instrumented and time consuming due to the application of the calcium phosphate coating to such medical implants

Method used

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  • Method and device for coating promoting bone growth

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0090] The mixture composed of 71.7 weight percent calcium sulfate dihydrate, 17.9 weight percent calcium carbonate, 8.8 weight percent palm palmitic acid triglyceride and 1.6 weight percent gentamicin sulfate was pressed into a diameter of 22mm, 10mm high cylinder. The cylinder was ground on both sides on a 27 mm diameter grit-blasted titanium disc. A dense, colorless coating is formed by grinding. The mass of the coating was 124.7 mg. The discs were stored in 5 ml of 0.1M phosphate buffer at 37°C. After one day the buffer was completely discarded and replaced with fresh buffer. On the second day and the seventh day, the buffer was changed again. The TDX analyzer of Abbott Company was used to determine the respective gentamicin contents in various buffer solutions.

[0091]

Embodiment 2

[0093] The mixture consisting of calcium sulfate dihydrate of 61.7 weight percent, strontium sulfate of 10.0 weight percent, calcium carbonate of 17.9 weight percent, palm wood palmitic acid triglyceride of 8.8 weight percent and gentamycin sulfate of 1.6 weight percent, using The eccentric press presses into a cylinder with a diameter of 15 mm and a height of 30 mm. The cylinder was ground on both sides on a 27 mm diameter grit-blasted titanium disc. A dense, colorless coating is formed by grinding. The mass of the coating was 111.2 mg.

Embodiment 3

[0095] The mixture consisting of calcium sulfate dihydrate of 61.7 weight percent, strontium sulfate of 10.0 weight percent, calcium carbonate of 17.9 weight percent, palm wood palmitic acid triglyceride of 8.8 weight percent and gentamycin sulfate of 1.6 weight percent, using The eccentric press presses into a cylinder with a diameter of 15 mm and a height of 30 mm. The cylinder was ground on both sides on a 27 mm diameter grit-blasted titanium disc. A dense, colorless coating is formed by grinding. The mass of the coating was 111.2 mg.

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Abstract

The invention relates to a method for coating of a medical implant that can be used to apply a calcium salt to the surface of a medical implant easily and without expensive coating equipment and little expenditure of time. Accordingly, a method is provided that includes (i) providing a medical implant that includes at least one surface to be coated; (ii) providing a body that includes at least one calcium salt with a Mohs hardness of no more than 5.5 on at least one of its surfaces; and (iii) rubbing said body having the calcium salt-containing surface onto the at least one medical implant surface to be coated in order to coat said surface of the medical implant with the at least one calcium salt.

Description

technical field [0001] The invention relates to a method for the coating of medical implants, the use of a body for the coating of medical implants and a plug for the coating of medical implants. Background technique [0002] Medical implants have long been used in medicine to support or replace bodily functions. Especially for defective native joints, joint implants are increasingly being used successfully for replacement, often accompanied by a significant improvement in the patient's quality of life. [0003] For hip, knee and shoulder replacements, uncemented artificial joints are increasingly being used in addition to cemented ones. Here, the uncemented artificial joint is usually made of a titanium alloy and has at least one roughened (usually sandblasted) or structured porous surface in order to improve bone tissue growth. [0004] Such attempts are known from the prior art to improve the compatibility of the implant surface with respect to the bone tissue. In this...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/32A61L27/30A61L27/54
CPCA61L27/12A61L27/32A61L2420/02A61L27/306B05D1/28C23C26/00
Inventor S·福格特H·比希纳
Owner HERAEUS MEDICAL