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3results about How to "Effective resistance" patented technology

Use of glutaroyl-coa dehydrogenase in inducing ferroptosis of liver cancer cells

PendingCN122357724ASolve key technical problemsEfficient killingGlutaric acidOncology
The application provides application of glutaroyl-CoA dehydrogenase in inducing ferroptosis of liver cancer cells, and belongs to the technical field of biotechnology.The application provides application of glutaroyl-CoA dehydrogenase (GCDH) in preparing products for evaluating risk of liver cancer and evaluating prognosis risk of liver cancer, and the tumor stage and T grade can be estimated by detecting the expression amount of GCDH, and the survival effect of liver cancer patients is evaluated.The application provides application of the overexpression reagent of GCDH in preparing products for inhibiting proliferation of liver cancer cells and inducing ferroptosis of liver cancer cells, and the ferroptosis of liver cancer cells is promoted by overexpressing GCDH in cells, and the colony formation ability of liver cancer cells is reduced.Further, the application provides application of the overexpression reagent of GCDH combined with a CA9 inhibitor in preparing products for inhibiting proliferation of liver cancer cells.
Owner:GUANGXI MEDICAL UNIVERSITY

Preparation method of hollow fiber composite loose nanofiltration membrane

The invention discloses a preparation method of a hollow fiber composite loose nanofiltration membrane, which specifically comprises the following processing steps: S1, firstly preparing materials, and manufacturing a hollow fiber membrane matrix; s2, manufacturing a composite loose layer; s3, carrying out cross-linking curing treatment on the membrane; s4, carrying out optimization treatment on the membrane; and S5, testing the performance of the film. According to the invention, the polyvinyl alcohol (PVA), the polyacrylic acid (PAA), the polyvinylpyrrolidone (PVP), the silicon dioxide, the carbon nano tube and the nano metal oxide are adopted as composite materials, and the selection and combination of the materials have relatively strong innovativeness in the field of nanofiltration membranes; the synergistic effect of the polymer and the nanoparticles is beneficial for improving the hydrophilicity, the separation performance and the anti-pollution capacity of the membrane.
Owner:QICHENG (JIANGSU) PURIFICATION TECH CO LTD