Spectrum sensing test method for concentration of biological solution

Abstract

The invention relates to a spectrum sensing test method for the concentration of biological solution. In the method, a real part and an imaginary part of a cladding index cannot be independent of each other and the requirement of Kramers-Kronig relations is met on the basis of a physical causality principle followed by an optical response of a cladding medium according to a causality principle. n alpha and n alpha' can be changed into a function of the concentration C of a component to be detected only by measuring or examining the inherent spectral absorption coefficient of the component to be detected in the cladding medium from a major manual. An unknown parameter is reduced to be beta gamma and C, and the concentration C of the component to be detected can be solved by using a simultaneousness intrinsic equation of a guide mode. The relevance coefficient of the method is between 0.9850 and 0.9961, the lowest detection limit is 0.1 mu M, a low-concentration trace test is realized, and clinical popularization significance is reflected.

Description

technical field [0001] The invention relates to an optical test technology, in particular to a spectral sensing test method for biological solution concentration based on a complex refractive index distribution strip waveguide. Background technique [0002] Tests such as drug analysis and bioactive substance analysis play an important role in life sciences and clinical medicine. Optical sensing has the advantages of non-destructiveness, fast signal generation and reading speed, and is the most widely used in this field so far. One of the testing techniques. Among them, there are many reports on the use of guided wave light or surface waves as signal carriers and the construction of integrated optical biochemical sensor devices, including early waveguide humidity sensors (K.Tiefenthaler et al., Opt.Lett., 1984,10 (4): 137- 139), and surface plasmon resonance biosensors developed in recent years (A.J.Haes et al., Expert Review of Molecular Diagnostics, 2004, 4:527-537; J.W.Ch...

AI Technical Summary

Problems solved by technology

These biosensors adopt a planar waveguide structure, and the input / output of light waves must use fine operation methods such as prism coupling. There are problems such as high working environment requirements and difficult test operations that hinder popularization and application.

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