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Ilex pubescens formula granules and preparation method thereof

A technology of formula granules and holly vulgaris, which is applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and bulk transportation, etc., can solve the problems of no patents on formula granules of holly The effect of no active ingredients and simple preparation process

Inactive Publication Date: 2012-01-25
江西省药物研究所
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  • Abstract
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AI Technical Summary

Problems solved by technology

[0004] At present, there is no patent related to Maodongqing formula granules and its preparation process

Method used

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Examples

Experimental program
Comparison scheme
Effect test

example 1

[0035] Take 4500g of the hollywort medicinal material, pulverize it, add 27000g of water, decoct for 2 hours, extract 3 times, combine and extract the medicinal liquid, filter, and the filtrate is concentrated under normal pressure to a clear paste with a relative density of 1.05~1.15, dried under reduced pressure, Grind into a dry powder to obtain about 360g of Ilex pubescens extract, add appropriate amount of soluble starch, make soft material with 80% ethanol in an appropriate amount, make granules, dry under normal pressure at 60°C, and granulate to obtain Ilex pubescens formula granules. Packed into bags, the specification is that every 1 gram is equivalent to 9 grams of the raw medicinal material of Ilex pubescens.

example 2

[0037] Take 4500g of holly holly, crush it, add 36000g of water, decoct for 3 hours, extract 3 times, combine and extract the medicinal liquid, filter, and concentrate the filtrate to a thick paste with a relative density of 1.20~1.30 under normal pressure, add dextrin and Appropriate amount of starch (1:1) mixture, made into soft materials, and then made into granules, dried under normal pressure at 60°C, granulated, and granulated with holly hair formula, divided into bags, and the specification is that every 2 grams of granules is equivalent to Mao Dongqing raw medicinal material 9 grams.

example 3

[0039] Take 4500g of hollywort medicinal material, crush it, add 45000g of water, decoct for 4 hours, extract twice, combine and extract the medicinal liquid, filter, and concentrate the filtrate to a clear paste with a relative density of 1.05~1.15 under normal pressure, and then dry it under reduced pressure , grind into dry powder, get 360g of holly holly extract, add appropriate amount of soluble starch, powdered sugar, dextrin (1:1:1) mixture, make soft material with appropriate amount of 80% ethanol, and then make granules, at 60°C Drying under normal pressure, granulation, to obtain the formula granules of Ilex pubescens, which is divided into bags, and the specification is that every 3 grams is equivalent to 22.5 grams of the raw medicinal material of Ilex pubescens.

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Abstract

The invention relates to ilex pubescens formula granules and a preparation method thereof, belonging to the preparation technique of traditional Chinese medicine granules. The preparation method comprises the following steps of: extracting ilex pubescens with water, concentrating, adding proper auxiliary materials, and preparing into the formula granules. The formula granules have stable and controllable quality, and the specification of the prepared formula granules is that 1-5 g of the formula granules is equivalent to 9-45 g of ilex pubescens. The formula granules can meet the requirements of clinical treatment according to syndrome difference and increase or decrease according to the syndrome, thereby facilitating agile matching of doctors. The formula granules provided by the invention replace the traditional ilex pubescens, have the advantages of high stability, agile formula and low administration dosage, and are easy to store and carry and convenient to use.

Description

technical field [0001] The invention relates to a hairy wintergreen formula granule and a preparation method thereof, belonging to the preparation technology of traditional Chinese medicine formula granules. Background technique [0002] Traditional Chinese medicine formula granules are also called traditional Chinese medicine granule decoction pieces, decoction-free decoction pieces, and single-flavor Chinese medicine concentrated granules. It is a new dosage form of traditional Chinese medicine decoction pieces made by scientifically processing single Chinese medicine and extracting active ingredients in Chinese herbal medicines. It is one of the development directions of Chinese medicine decoction pieces and one of the important research contents of the modernization of Chinese medicine. Clinical application and pharmacological experiments have shown that single Chinese medicine formula granules have basically the same curative effect and pharmacological effects as tradit...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61K9/16A61P9/00A61P9/10A61P11/00A61P11/04A61P17/02
Inventor 曾宪仪钟小群陈新菊郭晟袁海铭李忠贵李艳王丽静张俊明利家平罗强云夏平郑国安
Owner 江西省药物研究所
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