Collagen membrane medical dressing and preparation method thereof
A collagen film and collagen technology, applied in medical science, absorbent pads, bandages, etc., can solve the problems of obvious wound scars, high permeability, poor skin compatibility, etc., and achieve environmental protection and good biophase The effect of capacitive and simple preparation method
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Embodiment 1
[0036] Put 1.0 g of sodium carboxymethylcellulose into a reaction bottle with a stirrer and a thermometer, add 15 ml of deionized water, and stir evenly at 20°C to make it transparent and viscous; mix 0.05 g of dragon's blood with Mix 0.2 g of polyvinylpyrrolidone (PVP) evenly, and make a solid dispersion by melting method; add 0.05 g of collagen and 0.1 g of starch into 2 ml of glutaraldehyde solution, and stir evenly at a temperature of 20 ° C Make it fully dissolved, then mix the prepared transparent viscous sodium carboxymethyl cellulose solution with it, continue to stir at 35°C for 25 minutes, and prepare a paste mixture for later use; mix it in the prepared paste Add 0.05 gram of Panax notoginseng and 0.25 gram of solid dispersion in the liquid, stir evenly at a temperature of 35°C, then adjust the pH value of the pasty mixed solution with 5% sodium carbonate solution and 0.5mol / L acetic acid solution, and adjust the pH The value is controlled to 6, then poured into a m...
Embodiment 2
[0038]Put 6.0 grams of sodium carboxymethylcellulose into a reaction flask with a stirrer and a thermometer, add 60 milliliters of deionized water, and stir evenly at 25°C to make it transparent and viscous; mix 0.2 grams of dragon's blood with Mix 1.0 g of polyvinylpyrrolidone (PVP) evenly, and make a solid dispersion by melting method; add 0.1 g of collagen and 0.2 g of starch into 3 ml of glutaraldehyde solution, and stir evenly at a temperature of 25 ° C Make it fully dissolved, then mix the prepared transparent viscous sodium carboxymethyl cellulose solution with it, continue stirring at 30°C for 30 minutes, and prepare a paste mixture for later use; mix it in the prepared paste Add 0.2 gram of Panax notoginseng and 1.2 gram of solid dispersion in the liquid, stir evenly at a temperature of 30°C, then adjust the pH value of the pasty mixed solution with 5% sodium carbonate solution and 0.5mol / L acetic acid solution, and adjust the pH The value is controlled to 7, and then...
Embodiment 3
[0040] Put 7.0 grams of sodium carboxymethylcellulose into a reaction flask with a stirrer and a thermometer, add 70 milliliters of deionized water, and stir evenly at 30°C to make it transparent and viscous; mix 0.3 grams of dragon's blood with Mix 1.5% polyvinylpyrrolidone (PVP) evenly, and make a solid dispersion by melting method; add 0.2 g of collagen and 0.5 g of starch into 4 ml of glutaraldehyde solution, and stir evenly at a temperature of 28 ° C to make It is fully dissolved, and then mixed with the prepared transparent viscous sodium carboxymethyl cellulose solution, and continued to stir at 40°C for 20 minutes, and prepared into a paste mixture for later use; in the prepared paste mixture Add 0.3 gram of Panax notoginseng, 1.8 gram of solid dispersion, stir evenly at a temperature of 40°C, then adjust the pH value of the pasty mixture with 5% sodium carbonate solution and 0.5mol / L acetic acid solution, and adjust the pH value The control is 8, then poured into a mo...
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