Collagen membrane medical dressing and preparation method thereof

A collagen film and collagen technology, applied in medical science, absorbent pads, bandages, etc., can solve the problems of obvious wound scars, high permeability, poor skin compatibility, etc., and achieve environmental protection and good biophase The effect of capacitive and simple preparation method

Inactive Publication Date: 2012-03-21
SICHUAN NORMAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although it has the advantages of simple production and processing process, it still has the following defects: the permeability is too large, it is easy to dehydrate the wound surface; reduction, the cost of gauze is gradually increasing
So to sum up, the mainstream medical ...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Put 1.0 g of sodium carboxymethylcellulose into a reaction bottle with a stirrer and a thermometer, add 15 ml of deionized water, and stir evenly at 20°C to make it transparent and viscous; mix 0.05 g of dragon's blood with Mix 0.2 g of polyvinylpyrrolidone (PVP) evenly, and make a solid dispersion by melting method; add 0.05 g of collagen and 0.1 g of starch into 2 ml of glutaraldehyde solution, and stir evenly at a temperature of 20 ° C Make it fully dissolved, then mix the prepared transparent viscous sodium carboxymethyl cellulose solution with it, continue to stir at 35°C for 25 minutes, and prepare a paste mixture for later use; mix it in the prepared paste Add 0.05 gram of Panax notoginseng and 0.25 gram of solid dispersion in the liquid, stir evenly at a temperature of 35°C, then adjust the pH value of the pasty mixed solution with 5% sodium carbonate solution and 0.5mol / L acetic acid solution, and adjust the pH The value is controlled to 6, then poured into a m...

Embodiment 2

[0038]Put 6.0 grams of sodium carboxymethylcellulose into a reaction flask with a stirrer and a thermometer, add 60 milliliters of deionized water, and stir evenly at 25°C to make it transparent and viscous; mix 0.2 grams of dragon's blood with Mix 1.0 g of polyvinylpyrrolidone (PVP) evenly, and make a solid dispersion by melting method; add 0.1 g of collagen and 0.2 g of starch into 3 ml of glutaraldehyde solution, and stir evenly at a temperature of 25 ° C Make it fully dissolved, then mix the prepared transparent viscous sodium carboxymethyl cellulose solution with it, continue stirring at 30°C for 30 minutes, and prepare a paste mixture for later use; mix it in the prepared paste Add 0.2 gram of Panax notoginseng and 1.2 gram of solid dispersion in the liquid, stir evenly at a temperature of 30°C, then adjust the pH value of the pasty mixed solution with 5% sodium carbonate solution and 0.5mol / L acetic acid solution, and adjust the pH The value is controlled to 7, and then...

Embodiment 3

[0040] Put 7.0 grams of sodium carboxymethylcellulose into a reaction flask with a stirrer and a thermometer, add 70 milliliters of deionized water, and stir evenly at 30°C to make it transparent and viscous; mix 0.3 grams of dragon's blood with Mix 1.5% polyvinylpyrrolidone (PVP) evenly, and make a solid dispersion by melting method; add 0.2 g of collagen and 0.5 g of starch into 4 ml of glutaraldehyde solution, and stir evenly at a temperature of 28 ° C to make It is fully dissolved, and then mixed with the prepared transparent viscous sodium carboxymethyl cellulose solution, and continued to stir at 40°C for 20 minutes, and prepared into a paste mixture for later use; in the prepared paste mixture Add 0.3 gram of Panax notoginseng, 1.8 gram of solid dispersion, stir evenly at a temperature of 40°C, then adjust the pH value of the pasty mixture with 5% sodium carbonate solution and 0.5mol / L acetic acid solution, and adjust the pH value The control is 8, then poured into a mo...

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Abstract

The invention discloses a collagen membrane medical dressing, which is prepared in the way that: 1swung dash10 parts of sodium carboxymethylcellulose and 15swung dash150 parts of deionized water are mixed in a reaction bulb into the transparent thick state; 0.05swung dash0.5 part of resina draconis and 0.2swung dash2 parts of polyvidon are mixed and prepared into solid dispersoid through a liquation method; 0.05swung dash0.5 part of collagen and 0.1swung dash1 part of starch are added into 1swung dash5 parts of glutaraldehyde solution, are stirred to dissolve at 20 swung dash30 DEG C, then are mixed with the prepared sodium carboxymethylcellulose solution, and are stirred at 30swung dash50 DEG C, so a pasty mixed liquor is prepared for standby application; and 0.05swung dash0.5 part of pseudo-ginseng and 0.25swung dash2.5 parts of solid dispersion are added into the pasty mixed liquor, and are uniformly mixed at 30swung dash50 DEG C, the pH of the pasty mixed liquor is controlled between 6swung dash8, the pasty mixed liquor is poured into a die to form, and is dried in a drying oven, and the collagen membrane medical dressing product is produced only after the dyestripping.

Description

technical field [0001] The invention relates to a preparation technology of a medical dressing, and more specifically relates to a novel collagen medical dressing and a preparation method thereof, belonging to the technical field of medicine. Background technique [0002] With the rapid development of modern science and technology, the research on medical dressings has made gratifying progress, and many medical dressing materials with different structures and comprehensive functions have appeared. However, traditional plant medical dressings are still the main ones on the market. [0003] Medical dressings can temporarily protect wounds, prevent wound infection, and promote wound healing, and are more convenient to use as a medical material. Therefore, there are endless types of them, which are roughly as follows: 1. Traditional medical dressings, such as natural gauze, cotton pads, synthetic fibers, etc., provide effective protection for wounds by passively covering and abs...

Claims

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Application Information

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IPC IPC(8): A61L15/40A61L15/34A61L15/32A61L15/28A61L15/24A61L15/20A61L15/44
Inventor 杨华严娅尹静彭馨冉舒子斌
Owner SICHUAN NORMAL UNIVERSITY
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