Fritillary and loquat oral solution for treating cough and preparation method thereof

Abstract

The invention discloses a fritillary and loquat oral solution for treating cough and a preparation method thereof. The preparation method comprises the following steps of: (1) weighing raw materials; (2) decocting loquat leaf with water, filtering, concentrating to obtain clear paste, adding ethanol, fully mixing, standing, taking supernatant for later use; (3) pulverizing fritillary bulb, performing hot reflux extraction with ethanol on the fritillary bulb powder, balloonflower and perilla seed, filtering, combining the filtrate with the supernatant obtained in the step (2), recycling the ethanol, concentrating to obtain clear paste, cooling to room temperature, adding butanone for extraction, recycling the butanone and concentrating to obtain thick paste; drying, pulverizing and screening the thick paste to obtain extract powder; and (4) adding 10-50 parts by weight of distilled water and 5 parts by weight of flavoring agent to 1 part by weight of thick paste, and mixing uniformly to prepare an oral solution. The oral solution disclosed by the invention has the effects on relieving cough, eliminating phlegm and relieving asthma, and the oral solution prepared from the raw materials extracted by the extraction method disclosed by the invention has small drug dose, high drug content and good curative effects, and is convenient to take and carry, conductive to quantitative administration and convenient to store and transport.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine preparation, in particular to a Chuanbei loquat oral liquid for treating cough and a preparation method thereof. Background technique [0002] Cough Chuanbei Pipa Dew is prepared from traditional Chinese medicine raw materials: loquat leaves, platycodon grandiflorum, water pinellia, flat fritillaria liquid extract and menthol. Has antitussive and expectorant functions. For cough caused by cold and bronchitis. Its formula is: 68g of loquat leaves, 6g of platycodon grandiflorum, 20g of water pinellia, 7ml of flat fritillaria liquid extract, 0.15g of menthol. Once, filter, combine the filtrates, concentrate to an appropriate amount, add preservatives, filter, add 682g of sucrose, add flat fritillaria liquid extract and menthol in turn, add water to adjust to 1000ml, shake well, and get ready. [0003] The above-mentioned extraction method cannot fully extract the active ing...

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Problems solved by technology

[0003] The above-mentioned extraction method cannot fully extract the active ingredients, and the bioavailability is low, thereby affecting the performance of the drug effect and directly affecting the therapeutic effect. The patient takes a large dose

[0004] In addition, the raw material prescription contains water pinellia, which has the effect of drying dampness, resolving phlegm and relieving cough, but water pinellia is slightly poisonous.

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