Intraoperative motion area function locating system based on electroencephalogram slow cortex potential wavelet analysis

Abstract

The invention discloses an intraoperative motion area function locating system based on electroencephalogram slow cortex potential wavelet analysis. The system is used for collecting a cortex electroencephalogram signal by implanting an electrode array. The cortex electroencephalogram signal is processed by an amplifying filter and then input to a signal processing module through an A / D (Analogue / Digital) converter. An electroencephalogram signal pre-processing unit of the signal processing module is used for pre-processing and filtering data collected by each electrode through a decomposition and reconstruction algorithm of wavelet analysis. An SCP (Slow Cortex Potential) signal characteristic extraction unit and a mode classification unit are used for extracting and classifying characteristics by adopting SCP-based signal characteristic extraction and a classification algorithm, identifying specific attributes of each electrode and finally processing and outputting a functional area locating image. The locating system disclosed by the invention is capable of accurately, rapidly and non-invasively detecting an electroencephalogram signal in a motion functional area and outputting a brain motion area function locating image. By means of the specific analysis of the cortex electroencephalogram signal of the brain motion area, the clinical application of the intraoperative functional location of the brain cortex motion area in a human-body nerve surgery is realized.

Description

technical field [0001] The invention relates to the field of medical electronic equipment, in particular to an intraoperative motor zone function positioning system based on brain electricity slow cortical potential wavelet analysis. Background technique [0002] Lesions of functional areas of the brain ， It mainly refers to tumors, vascular malformations and epileptic foci located in the motor, sensory and language areas. The incidence rate of the large-scale investigation report organized by the World Health Organization in my country is only 8‰ of epilepsy. The existing epilepsy patients in our country More than 10 million people, of which drug-refractory epilepsy accounts for about 30% of epilepsy patients. At present, 3 million refractory epilepsy patients in my country need surgical treatment, which does not include low-grade gliomas and metastatic tumors located in functional areas , primary benign tumors, cavernous hemangiomas and arteriovenous malformations. Lesions...

AI Technical Summary

Problems solved by technology

[0007]Intraoperative direct electrical stimulation of the cortex or subcortex based on electrophysiological techniques allows real-time determination of cortical and subcortical functional areas of brain functions such as motor, sensory, language, and even memory Localization is currently the most accurate and credible method for locating brain functional areas. The accuracy of intraoperative direct electrical stimulation of the cortex or subcortex based on electrophysiological techniques can reach about 5 mm; however, electrical stimulation may damage the cerebral cortex, Triggers problems such as seizures and secondary surgery, and the operation time lasts from 0.5 to several hours

[0008]The defects of the above-mentioned functional area positioning methods have been manifested in the practice of neurosurgery. Traditional surgical functional positioning techniques cannot fully distinguish and grasp the relationship between functional structures and lesions. It is very easy to cause damage to brain function and structure during the resection of the lesion. According to statistics, the permanent neurological damage complication of traditional surgery is 13-27%

In addition, since functional zone lesions are prone to serious complications, surgeons are not active in surgical resection, and palliative resection is often performed. For example, the complete resection and subtotal resection rate of low-grade gliomas are only 43%.

This not only makes the postoperative treatment of the lesion difficult, but also easily causes the recurrence of the disease or the symptoms are difficult to control, which seriously affects the prognosis of the treatment.

[0009] It can be seen that the current neurocortical (motor area) function localization method cannot fully meet the needs of brain function area surgery in terms of speed, accuracy and safety

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