Method for extracting general flavone from sorrel shell waste residues through microwave refluxing

A technology of microwave reflux and total flavonoids is applied in the directions of pharmaceutical formulations, non-central analgesics, medical preparations containing active ingredients, etc., to achieve the effects of improving the utilization rate, shortening the extraction time, and improving the extraction efficiency.

Inactive Publication Date: 2012-07-04
NORTH CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the use of microwaves to extract and purify natural products such as medicines and foods is receiving widespread attention. However, after searching, there is no report on the method of using microwave reflux to extract total flavonoids in the waste residue of chestnut hair shells.

Method used

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  • Method for extracting general flavone from sorrel shell waste residues through microwave refluxing
  • Method for extracting general flavone from sorrel shell waste residues through microwave refluxing

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The chestnut hair shell that removes impurity is broken into 40 order powders with crusher. Take the material and adjust the material ratio to 1:25 with 45% ethanol. After soaking for 40 minutes, put it in a microwave oven reflux device, extract it for 10 minutes under a microwave power level of 450W, and remove it for suction filtration to obtain the total flavonoid extraction solution. The filter residue was extracted again, concentrated by rotary evaporation under reduced pressure to obtain crude flavonoids, and the ethanol was recycled. The content of the total flavonoids in the concentrate is determined by aluminum chloride colorimetry, and the extraction rate of the total flavonoids is 85%, the purity is 40%, and the yield is 0.19%.

[0023] The extracted flavonoids were separated and purified to scan the IR spectrum of the small sample. Get the graph (see attached figure 1 , 2), analyze and compare, determine that the product contains flavonoids.

[0024] The ...

Embodiment 2

[0029] The chestnut hair shell that removes impurity is broken into 60 purpose powder material with crusher. Take the material and adjust the material ratio to 1:40 with 50% ethanol. After soaking for 60 minutes, put it in a microwave oven reflux device, extract it for 18 minutes under a microwave power level of 180w, and remove it for suction filtration to obtain the total flavonoids leaching solution. Extract the filter residue once more, combine the two extracts, concentrate by rotary evaporation under reduced pressure to obtain the total flavonoids of the product, and recycle the ethanol. The content of total flavonoids in the concentrate was determined by aluminum chloride colorimetry. The extraction rate of total flavonoids obtained was 93%, the purity was 45%, and the yield was 0.20%.

Embodiment 3

[0031] The chestnut hair shell that removes impurity is broken into 50 mesh powders with crusher. The material was adjusted to 1:50 with 55% ethanol, soaked for 50 minutes, placed in a microwave oven reflux device, leached for 25 minutes at a microwave power level of 150W, removed and suction filtered to obtain the total flavonoids leaching solution. Extract the filter residue once more, collect all the solutions, concentrate by rotary evaporation under reduced pressure to obtain the total flavonoids of the product, and recycle the ethanol. The content of total flavonoids in the concentrate was determined by aluminum chloride colorimetry. The extraction rate of total flavonoids obtained was 88%, the purity was 42%, and the yield was 0.19%.

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Abstract

The invention discloses a method for extracting general flavone from sorrel shell waste residues through microwave refluxing. The method comprises the following specific steps of: 1, removing impurities from naturally-dried sorrel shells, smashing, sieving with a sieve of 40-60 meshes, and putting into a constant-temperature drying oven for drying sorrel shell powder for later use; and 2, uniformly fixing the powder treated in the step 1 with 30-60 percent of ethanol in the weight volume ratio of 1:25-1:50, performing reflux leaching at microwave power for 10-25 minutes, performing suction filtration to obtain a general flavone extracting solution, removing ethanol by rotationally evaporating, and performing vacuum drying to obtain a general flavone solid. The content of general flavone in a concentrated solution is measured with an aluminum chloride colorimetric method. According to measurement, the extraction ratio of general flavone is 95 percent, and the yield is 0.20 percent. The method has the advantages of quickness, high extraction ratio, environmental friendliness and nontoxicity by taking ethanol water as a solvent, simple equipment operation, small solvent using amount, easiness for recovering and suitability for expanded production in plants. The method has wide application prospects in medicines and foods.

Description

technical field [0001] The invention relates to a method for extracting active substances in plants, more precisely, it is a microwave reflux extraction method for total flavonoids in chestnut shells. Background technique [0002] The chestnut hair shell is the involucre of the Fagaceae plant chestnut, also known as the chestnut thorn shell, the wind chestnut shell, the chestnut hair ball, the chestnut shell, and the chestnut involucre. According to the "Dictionary of Traditional Chinese Medicine", the chestnut shell is sweet, flat, astringent, and non-toxic. It is used as antibacterial and anti-inflammatory herbal medicine in the folk. Pharmacological studies have shown that the water decoction, alcohol solubles, and ethyl acetate extracts of chestnut involucre all have antibacterial activity. The waste residue of chestnut hair shells is rich in flavonoids, and flavonoids have broad application prospects in medicine and food. Reprocessing these waste chestnut hair shell r...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/185A61P1/14A61P39/02A61P17/00A61P31/06A61P31/04A61P29/00A23L1/29A23L33/00
Inventor 刘淑萍陈立棉赵艳琴闫路省
Owner NORTH CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY
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