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A kind of water extract refining method of traditional Chinese medicine composition

A refining method and composition technology, which is applied in the direction of drug combination, pharmaceutical formula, medical preparations containing active ingredients, etc., can solve the problems of long production cycle, loss of active ingredients, heat damage, etc., and achieve the effect of satisfying industrial rapid production

Active Publication Date: 2016-03-02
BEIJING YILING PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The refining of traditional Chinese medicine is mostly based on the polarity difference between components (solvent precipitation or extraction, adsorption separation, etc.) Component loss or heat damage, resulting in reduced efficacy, etc.

Method used

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  • A kind of water extract refining method of traditional Chinese medicine composition
  • A kind of water extract refining method of traditional Chinese medicine composition
  • A kind of water extract refining method of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068] The API formula is :

[0069] Ginseng 89g Ophiopogon 112g Dogwood 224g Salvia 224g

[0070] Fried sour jujube kernels 186g mulberry parasite 186g red peony 89g soil turtle worm 75g

[0071] Gansong 89g Coptis 45g Southern Schisandra 67g Keel 149g

[0072] The refining method is :

[0073] (a) in the above-mentioned prescription, ginseng is extracted three times with 70% ethanol reflux, the first time is 3 hours, and each time is 2 hours later, merge the extract, filter, reclaim ethanol, concentrate, dry, pulverize into fine powder, standby;

[0074] (b) in the above-mentioned prescription, Fructus Schisandrae, Cornus officinalis, Salvia miltiorrhiza, Coptis chinensis, Gansong are extracted three times with 70% ethanol reflux, merge extract, filter, reclaim ethanol, concentrate to obtain extract, for subsequent use;

[0075] (c) in above-mentioned prescription, soil soft-shelled turtle is crushed into fine powder, for subsequent use;

[0076] (d) in the above-men...

Embodiment 2

[0082] The API formula is:

[0083] Ginseng 45g Ophiopogon japonicus 112g Cornus 224g Salvia 225g Fried Suanzao Ren 186g Mulberry parasite 186g Red peony 89g Gansong 45g Turmeric 35g Coptis chinensis 45g Southern Schisandra 67g keel 149g.

[0084] The refining method is :

[0085] (a) in the above-mentioned prescription, ginseng is extracted three times with 70% ethanol reflux, the first time is 3 hours, and each time is 2 hours later, merge the extract, filter, reclaim ethanol, concentrate, dry, pulverize into fine powder, standby;

[0086] (b) in the above-mentioned prescription, Fructus Schisandrae, Cornus officinalis, Salvia miltiorrhiza, Coptis chinensis, Gansong are extracted three times with 70% ethanol reflux, merge extract, filter, reclaim ethanol, concentrate to obtain extract, for subsequent use;

[0087] (c) in above-mentioned prescription, soil soft-shelled turtle is crushed into fine powder, for subsequent use;

[0088] (d) in the above-mentioned prescripti...

Embodiment 3

[0094] The API formula is:

[0095] Ginseng 175g Ophiopogon japonicus 192g Cornus 421g Salvia 440g Fried Suanzao Ren 395g Mulberry parasite 396g Red peony root 188g Turmeric 98g Gansong 188g Coptidis 85g Southern Schisandra 147g keel 278g.

[0096] The refining method is :

[0097] (a) in the above-mentioned prescription, ginseng is extracted three times with 70% ethanol reflux, the first time is 3 hours, and after each 2 hours, the extract is merged, filtered, and ethanol is recovered, concentrated, dried, and pulverized into fine powder, for subsequent use;

[0098] (b) in the above-mentioned prescription, Fructus Schisandrae, Cornus officinalis, Salvia miltiorrhiza, Coptis chinensis, Gansong are extracted three times with 70% ethanol reflux, merge the extract, filter, reclaim ethanol, and concentrate to obtain extract, for subsequent use;

[0099] (c) in above-mentioned prescription, soil soft-shelled turtle is crushed into fine powder, for subsequent use;

[0100] (d...

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PUM

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Abstract

The invention discloses a method for refining the extract of a traditional Chinese medicine composition. The traditional Chinese medicine composition is composed of traditional Chinese medicines such as ginseng, Ophiopogon japonicus, dogwood, salvia miltiorrhiza, fried jujube seed, mulberry, red peony root, ground beetle, nard pine, etc., and can effectively treat ventricular premature beats of coronary heart disease. The method adopts inorganic ceramic membrane filtration to refine the extract of the traditional Chinese medicine composition. The method has high effective component transfer rate, can be industrially produced, has simple material liquid treatment, convenient cleaning of the inorganic ceramic membrane, and can be regenerated repeatedly.

Description

technical field [0001] The invention relates to a method for refining the water extract of a Chinese medicine composition, in particular to a method for refining the water extract of a Chinese medicine composition through inorganic ceramic membrane filtration. Background technique [0002] The main purpose of the production process of traditional Chinese medicine preparations is to enrich the active ingredients and remove invalid impurities. The refining of traditional Chinese medicine is mostly based on the polarity difference between components (solvent precipitation or extraction, adsorption separation, etc.) Component loss or heat damage, resulting in reduced efficacy, etc. Inorganic ceramic membrane separation technology is based on the principle of sieving, which can separate suspended particles of 0.05-10 μm and some macromolecular impurities in the solution. Inorganic ceramic membranes for traditional Chinese medicine separation are mostly Al 2 o 3 The ceramic me...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8968A61P9/06A61K35/02A61K35/64
Inventor 王曙宾郭珊珊周东明黄开毅
Owner BEIJING YILING PHARMA
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