Al technical title is built by PatSnap Al team. It summarizes the technical point description of the patent document.
A technology of calcium aspartate and aspartic acid, which is applied in the field of medicine, can solve the problems of cumbersome methods, unfavorable industrial production, and many steps, and achieve the effects of high yield, great application value, and simple methods
Inactive Publication Date: 2012-10-17
上海腾瑞医药技术有限公司 +1
View PDF3 Cites 8 Cited by
Summary
Abstract
Description
Claims
Application Information
AI Technical Summary
This helps you quickly interpret patents by identifying the three key elements:
Problems solved by technology
Method used
Benefits of technology
Problems solved by technology
This method is cumbersome and involves many steps
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more
Image
Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
Click on the blue label to locate the original text in one second.
Reading with bidirectional positioning of images and text.
Smart Image
Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0023] L-Aspartic Acid 15.7kg
[0024] Calcium carbonate 5.9kg
[0025] Purified water 65.7kg
[0026] Preparation:
[0027] (1) Add 44.9kg of purified water into the reaction pot, put in L-aspartic acid and calcium carbonate, then add 20.8kg of purified water, heat while stirring, and keep the temperature of the reaction liquid at 75-85°C for 1.5 hours;
[0028] (2) Let the reacted feed liquid stand still for 10 hours (25°C), filter, and take the supernatant;
[0029] (3) The supernatant was spray-dried, and the dry powder was collected to obtain 17.6 kg of calcium L-aspartate, with a yield of 97.50%. Calcium content 12.2%
[0030] (The detection method is based on the Shanghai Enterprise Standard Q / VAGH 5-2007 index: Calcium (calculated as Ca2+), 12±1%)
Embodiment 2
[0032] L-Aspartic Acid 15.7kg
[0033] Calcium carbonate 6.79kg
[0034] Purified water 65.7kg
[0035] Preparation:
[0036] (1) Add 44.9kg of purified water to the reaction pot, add L-aspartic acid and calcium carbonate, then add 20.8kg of purified water, heat while stirring, and keep the temperature of the reaction solution at 75-85°C for 2.5 hours;
[0037] (2) Let the reacted feed liquid stand still for 18 hours (25°C), filter, and take the supernatant;
[0038] (3) The supernatant was spray-dried, and the dry powder was collected to obtain calcium L-aspartate (17.2Kg). The yield is 99.50%. Calcium content 12.6%.
Embodiment 3
[0040] L-Aspartic Acid 15.7kg
[0041] Calcium carbonate 7.67kg
[0042] Purified water 65.7kg
[0043] The preparation method is the same as in Example 1.
[0044] The yield of calcium L-aspartate is 98.50%. Calcium content 12.1%
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
PUM
Login to view more
Abstract
The invention provides L-calcium aspartate. The L-calcium aspartate comprises the following components, by weight, 0.9-1.1 parts of L-aspartic acid, 0.4-0.5 part of calcium carbonate and 4.2 parts of pure water. The L-calcium aspartate the invention, which is used as a nutrition intensifying agent, enters the small intestine after stably going through the stomach, and slowly releases calcium ions for being absorbed by human bodies, the molecular structure of the L-calcium aspartate is similar to the molecular structure of dipeptide protein calcium which is in natural foods and is most easily absorbed by the intestinal tract, and results of Shanghai disease control center detection show that the content of blood calcium in the L-calcium aspartate is 84.5mug/ml and the content of blood calcium in a blank control group is 6.6mug/ml. By statistical processing, the difference has a significance (P is less than 0.005). The method has the advantages of less relating equipment and simplicity, and allows the yield of the L-calcium aspartate to reach 99.50%; and the calcium content is 12.1-12.6%, so the method is suitable for industrialized production and has a large application value.
Description
technical field [0001] The invention relates to medicines, in particular to calcium L-aspartate and a preparation method thereof. Background technique [0002] Calcium is the basic raw material for bone development and has other important physiological functions in the body. These functions play an important role in maintaining the health of the body and ensuring the smooth progress of normal growth and development. For example, calcium can promote the activity of certain enzymes in the body, regulate the activity of enzymes; participate in the activity of nerves and muscles and the release of neurotransmitters; regulate the secretion of hormones. Calcium is also needed for blood coagulation, cell adhesion, and muscle contraction. Calcium also has the functions of regulating heart rhythm, reducing cardiovascular permeability, controlling inflammation and edema, and maintaining acid-base balance. CN1817855A has reported the preparation method of L-aspartic acid chelated ca...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more
Application Information
Patent Timeline
Application Date:The date an application was filed.
Publication Date:The date a patent or application was officially published.
First Publication Date:The earliest publication date of a patent with the same application number.
Issue Date:Publication date of the patent grant document.
PCT Entry Date:The Entry date of PCT National Phase.
Estimated Expiry Date:The statutory expiry date of a patent right according to the Patent Law, and it is the longest term of protection that the patent right can achieve without the termination of the patent right due to other reasons(Term extension factor has been taken into account ).
Invalid Date:Actual expiry date is based on effective date or publication date of legal transaction data of invalid patent.
Login to view more 
Login to view more