Chinese medicinal composition for promoting healing after boneblast, as well as preparation method and application thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine, can solve problems such as poor blood supply around fractures, pain of patients, imperfect fixation, etc.

Inactive Publication Date: 2012-10-24
如皋市江北添加剂有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The main reasons for delayed union after fracture surgery are: 1. Incomplete fixation. The purpose of fracture fixation is not only to maintain good contact with the fracture ends, but also to eliminate the stress that is not conducive to fracture healing, that is, muscle contraction force, the gravity of the limbs, If the fixation cannot stop the unfavorable movement of the fracture end due to the shear force and rotational stress generated during physical activity, it will definitely affect the repair process of the fracture;

Method used

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  • Chinese medicinal composition for promoting healing after boneblast, as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Example Embodiment

[0084] Example 1 Ointment 1 prepared by the present invention

[0085] Rhizoma Drynariae 82g, Morinda officinalis 46g, Dipsacus 30g, Millennium Health 38g, Salvia 30g, Triangle 23g, Puhuang 26g, Saffron 24g, Big Leaf Purple Pearl 19g, Hematoxylin 25 grams, 18 grams of dragon blood, 21 grams of angelica, 15 grams of spatholobi, 42 grams of ginseng, 29 grams of Polygonatum, 31 grams of acanthopanax, 13 grams of borneol, 11 grams of frankincense, 13 grams of Citrus aurantium mixed, crushed by 20B universal Machine (produced by Hilton Pharmaceutical Equipment Co., Ltd., Changzhou City, Jiangsu Province) crushed and sieved to obtain 100 mesh powder. The obtained powder was mixed with 1700 grams of ethanol with an alcohol concentration of 90% and extracted 3 times under reflux, filtered, combined the filtrate, and reduced Press and concentrate to remove ethanol to obtain dry paste. Put the obtained dry paste into a QM-3SP4J planetary high-energy ball mill (manufactured by Nanjing Unive...

Example Embodiment

[0086] Example 2 Animal experiment

[0087] Experimental animal

[0088] There are 58 healthy 5-month-old New Zealand big-eared white rabbits, half male and half male, weighing 2.0-2.5kg / head.

[0089] Experimental drug

[0090] Therapeutic group: the traditional Chinese medicine ointment 1 prepared in Example 1, the ingredients of the traditional Chinese medicine ointment were evenly coated, so as to be absorbed into the elastic sterile absorbent cotton yarn to make a functional lining material;

[0091] Control group: Traumatology Jiegu tablets.

[0092] Experiment grouping

[0093] According to the principle of random grouping, 58 New Zealand white rabbits were divided into treatment group, control group and blank group, with 16 rabbits in each group, and 10 rabbits were selected for toxicity experiment.

[0094] Method of establishing animal model and method of administration

[0095] 58 New Zealand rabbits were fasted overnight without water. Before the operation, they were anesthetize...

Example Embodiment

[0117] Example 3 Medicinal wine 1 prepared by the present invention

[0118] Rhizoma Drynariae 82g, Morinda officinalis 46g, Dipsacus 30g, Millennium Health 38g, Salvia 30g, Triangle 23g, Puhuang 26g, Saffron 24g, Big Leaf Purple Pearl 19g, Hematoxylin 25 grams, 18 grams of dragon blood, 21 grams of angelica, 15 grams of spatholobi, 42 grams of ginseng, 29 grams of Polygonatum, 31 grams of acanthopanax, 13 grams of borneol, 11 grams of frankincense, 13 grams of Citrus aurantium mixed, crushed by 20B universal Machine (produced by Hilton Pharmaceutical Equipment Co., Ltd., Changzhou City, Jiangsu Province) crushed and sieved to obtain a powder of 100 mesh. The powder obtained was mixed with 1700 grams of ethanol with an alcohol concentration of 90%, and extracted 3 times under reflux, filtered, combined the filtrate, and reduced Press and concentrate to remove ethanol to obtain a dry paste. Put the obtained dry paste into a QM-3SP4J planetary high-energy ball mill (produced by Nan...

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Abstract

The invention provides a Chinese medicinal composition for promoting healing after boneblast, and the Chinese medicinal composition is prepared from the following raw materials: drynaria rhizome, morinda officinalis, teasel root, obscured homalomena rhizome, red-rooted salvia root, common burreed rhizome, cattail pollen, saffron, bigleaf beautyberry leaf, sappanwood, dragon's blood, Chinese angelica, suberect spatholobus stem, ginseng, sealwort, slenderstyle acanthopanax bark,borneol, frankincense and immature orange fruit. The Chinese medicinal composition has the functions of activating blood circulation and removing stasis, promoting circulation of vital energy and blood, eliminating stasis and removing stagnation, promoting new bone proliferation and accelerating fracture healing, and can be used for overcoming various defects in Western medicine promoting healing after boneblast.

Description

Technical field [0001] The present invention relates to the technical field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for promoting postoperative healing of fractures. Background technique [0002] Fracture is a common clinical disease. In sports, traffic accidents and daily life, bumps and bumps are inevitable. In addition, recent natural disasters such as earthquakes and tsunamis have increased the incidence of this disease. Especially after the earthquake, there will be a large number of fracture patients. According to statistics from the National Health Organization, more than 3 million people in my country suffer from fractures each year. [0003] The conventional treatment method after fracture is to reset the fracture and then fix it with plaster, relying on the bone regeneration ability to make it heal naturally; for more severe fracture patients, surgical treatment is required, and the fracture is treated with steel needl...

Claims

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Application Information

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IPC IPC(8): A61K36/902A61K9/70A61P19/08A61K31/045
Inventor 许梅
Owner 如皋市江北添加剂有限公司
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