Medicinal extract composition for treating psychoneurosis and preparation method and preparation thereof

A neurosis and composition technology, which is applied in the field of drug extract composition for treating neurosis and its preparation and preparation, can solve the problem of unretrieved patent data and the like, and achieves fast onset, fast absorption, The effect of improving the therapeutic effect

Active Publication Date: 2012-12-05
JINHE TIBETAN MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0004] The patent search did not retrieve th

Method used

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  • Medicinal extract composition for treating psychoneurosis and preparation method and preparation thereof
  • Medicinal extract composition for treating psychoneurosis and preparation method and preparation thereof
  • Medicinal extract composition for treating psychoneurosis and preparation method and preparation thereof

Examples

Experimental program
Comparison scheme
Effect test

experiment example 1

[0044] Experimental example 1, volatile oil extraction process

[0045] Extraction method of volatile oil

[0046] Weigh 25g of betel nut, 20g of agarwood, 7.5g of clove, 6.25g of nutmeg, 12.5g of woody incense, 10g of kaempferia according to the formula ratio, mix them, put them in a round bottom flask, soak for a certain period of time, add a certain amount of water to extract until the volume of volatile oil reaches When changes occur again, collect the volatile oil and dehydrate it with anhydrous sodium sulfate to obtain an orange-yellow oil. Read the volume of the volatile oil and compare it with the maximum oil recovery to obtain the relative oil recovery.

[0047]

[0048] Extraction Time Examination

[0049]Accurately weigh 25g of betel nut, 20g of agarwood, 7.5g of clove, 6.25g of nutmeg, 12.5g of woody incense, and 10g of kangaroo according to the proportion of the formula. , extract the volatile oil, record the oil recovery at different extraction times, the re...

experiment example 2

[0058] Experimental example 2, ethanol extraction process

[0059] Experimental Investigation of Different Ethanol Concentrations

[0060] Process 1 (volume concentration 30% ethanol) accurately weigh 25g of betel nut, 20g of agarwood, 7.5g of clove, 6.25g of nutmeg, 12.5g of woody fragrance, and 10g of kaempferia, put them in a 1000ml round bottom flask, add 6 times the amount of water to extract the volatile oil, Collect the volatile oil, filter, add 10g of jujube, 7.5g of longum longum, 8.75g of black pepper, and 15g of iron bar hammer to the dregs, add 30% ethanol twice, add 8 times the amount each time, extract for 1.5 hours, filter, Concentrate to recover ethanol and dry.

[0061] Process 2 (volume concentration 50% ethanol) accurately weigh 25g of betel nut, 20g of agarwood, 7.5g of clove, 6.25g of nutmeg, 12.5g of woody incense, and 10g of kaempferia, put them in a 1000ml round bottom flask, add 6 times the amount of water to extract the volatile oil, Collect the vol...

experiment example 4

[0090] Experimental example 4. Stability test of inclusion compound of volatile oil

[0091] Take 5ml of volatile oil to prepare clathrate according to the clathrate method of Example 1, take the above clathrate and add 180g dextrin to make granules, dry, pack, and pack 2g in each bag.

[0092] Take dextrin to make granules, spray into 5ml ethanol solution of volatile oil, moisten, evaporate ethanol, pack, 2g per bag.

[0093]Put the above-packed granules under the same conditions (temperature 40°C±2°C, humidity 75%±5%) for 0, 1, 2, 3, and 6 months, and test the volatile oil content. The results are shown in Table 7.

[0094] Table 7 The investigation result of inclusion on the stability of volatile oil

[0095]

[0096] The result shows, volatile oil does not contain group, and the volatile oil contained in the particle loses bigger, and although the volatile oil after clathrate reduces to some extent, but little change, therefore volatile oil of the present invention use...

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Abstract

The invention discloses a medicinal extract composition for treating psychoneurosis and a preparation method and a preparation thereof. The method comprises the following steps of: preparing a volatile oil clathrate compound; preparing an ethanol extract; crushing mineral medicines to be used as medicines; and performing superfine grinding on animal medicines, and dispersing solids. The medicinal preparation is prepared from the medicinal extract composition. According to the medicinal extract composition, on the basis of taking Tibetan medicine nerve soothing pills as raw materials, the new extraction preparation method is adopted; and the medicinal extract composition is extracted in a mode of extracting volatile oil by using water vapor and a mode of ethanol extracting according to the physicochemical properties of chemical ingredients contained in medicinal materials involved in a formula, and expensive and fine medicinal materials are used as the medicines directly in a raw medicinal powder mode, so that medicinal effect ingredients are ensured, the curative effect of the medicines is improved, and the safety of the medicines is enhanced. Compared with the conventional preparation, the medicinal preparation prepared by the method has the advantages that on the premise of keeping the medicinal effect of the original preparation, the medicinal preparation is high in absorption speed, quick in response and high in bioavailability, and active ingredients can be concentrated to lesion sites effectively.

Description

technical field [0001] The invention relates to a traditional Chinese medicine extract composition, a preparation method and a preparation thereof, in particular to a medicine extract composition, a preparation method and a preparation for treating neurosis. Background technique [0002] Neurosis, also known as neurosis and psychosis, is a group of non-psychiatric functional disorders. Its common features are: it is a group of psychogenic mental disorders, personality factors and psychosocial factors are the main pathogenic factors, but it is not a stress disorder, it is a group of functional disorders, and the nature of the disorder is functional and non-organic; Symptoms in both physical and physical aspects; have a certain basis of personality traits but are not personality disorders; each subtype has its own characteristic clinical phase; neurosis is reversible, aggravated when external pressure is high, otherwise the symptoms are relieved or disappear; social function i...

Claims

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Application Information

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IPC IPC(8): A61K36/906A61K47/40A61K47/34A61P25/00A61K35/34A61K33/20A61K47/10
Inventor 常建辉马宏伟彭坤高英涵江兆英赵丽丽王京凯
Owner JINHE TIBETAN MEDICINE
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