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Pharmaceutical composition for livestock heat clearing and livestock detoxifying and preparation method thereof

A composition and drug technology, applied in the field of veterinary antipyretic and detoxifying drug compositions and preparation, can solve the problems of drug residues and drug resistance, lack of therapeutic drugs, abuse of antibiotics, etc., and achieve no toxic side effects and high bioavailability , easy to operate effect

Active Publication Date: 2012-12-12
ZHENGZHOU HOUYI PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For the above diseases, there is a lack of clinically effective therapeutic drugs, and the antibacterial and antiviral drugs used are likely to cause drug residues and drug resistance, and there is a phenomenon of abuse of antibiotics

Method used

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  • Pharmaceutical composition for livestock heat clearing and livestock detoxifying and preparation method thereof
  • Pharmaceutical composition for livestock heat clearing and livestock detoxifying and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] The veterinary antipyretic and detoxifying pharmaceutical composition of this example, the compound composition is: 1.5g of Scutellaria baicalensis extract, 6g of honeysuckle, 9g of Artemisia annua, 12g of forsythia, 9g of wild chrysanthemum, 9g of Hedyotis diffusa, 0.1 ursodeoxycholic acid g.

[0031] The preparation method of this pharmaceutical composition comprises the following steps:

[0032] 1) Weigh 6g of honeysuckle, 9g of Artemisia annua, 12g of forsythia, 9g of wild chrysanthemum, and 9g of Hedyotis diffusa, add water to decoct for 1.5h, the mass ratio of the amount of water added to the decoction drug is 10:1, collect the distillate, and then Decoct for 1 hour, filter the decoction with water, combine and concentrate the filtrate to an appropriate amount;

[0033] 2) After cooling the liquid obtained in step 1), add ethanol to make the alcohol content of the liquid reach 65%, refrigerate and let it stand for 48 hours, take the supernatant and filter it with...

Embodiment 2

[0037] The veterinary antipyretic and detoxifying pharmaceutical composition of this example, the compound composition is: 1.5g of Scutellaria baicalensis extract, 10g of honeysuckle, 15g of Artemisia annua, 24g of forsythia, 15g of wild chrysanthemum, 23g of Hedyotis diffusa, 0.3 ursodeoxycholic acid g.

[0038] The preparation method of this pharmaceutical composition comprises the following steps:

[0039] 1) Weigh 10g of honeysuckle, 15g of Artemisia annua, 24g of forsythia, 15g of wild chrysanthemum, and 23g of Hedyotis diffusa, add water to decoct for 1.5h, the mass ratio of the amount of water added to the decoction medicine is 10:1, collect the distillate, and then Decoct for 1 hour, filter the decoction with water, combine and concentrate the filtrate to an appropriate amount;

[0040] 2) After cooling the liquid obtained in step 1), add ethanol to make the alcohol content of the liquid reach 65%, refrigerate and let it stand for 48 hours, take the supernatant and fi...

Embodiment 3

[0044] The veterinary antipyretic and detoxification pharmaceutical composition of this example, the compound composition is: 1.5g of Scutellaria baicalensis extract, 15g of honeysuckle, 21g of Artemisia annua, 36g of forsythia, 21g of wild chrysanthemum, 36g of Hedyotis diffusa, 0.5 ursodeoxycholic acid g.

[0045] The preparation method of this pharmaceutical composition comprises the following steps:

[0046] 1) Weigh 15g of honeysuckle, 21g of Artemisia annua, 36g of forsythia, 21g of wild chrysanthemum, and 36g of Hedyotis diffusa, add water to decoct for 1.5h, the mass ratio of the amount of water added to the decoction medicine is 10:1, collect the distillate, and then Decoct for 1 hour, filter the decoction with water, combine and concentrate the filtrate to an appropriate amount;

[0047] 2) After cooling the liquid obtained in step 1), add ethanol to make the alcohol content of the liquid reach 65%, refrigerate and let it stand for 48 hours, take the supernatant and...

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Abstract

The invention discloses a pharmaceutical composition for livestock heat clearing and livestock detoxifying and a preparation method thereof. The compound pharmaceutical composition comprises radix scutellariae extract, fructus forsythiae, Artemisia apiacea, honeysuckle, chrysanthemum indicum, Oldenlandia and ursodesoxycholic acid. The preparation method for preparing the pharmaceutical composition into oral liquid includes steps of firstly, decocting medical materials with water for 1.5 hours, collecting distillate, decocting again for 1 hour, filtering water decoction, and combining filtrate for concentration to an appropriate amount; secondly, cooling, adding ethanol, taking supernate for suction filtration, and removing ethanol in filtrate under reduced pressure; thirdly, adding distillate, ursodesoxycholic acid and radix scutellariae extract, adjusting pH with sodium hydroxide solution, and adding water for injection to full dose; and fourthly, refrigerating for 48 hours, performing refine filtration, split charging, and performing light inspection. The pharmaceutical composition has fine preventive and therapeutic effect in cold, fever, atypical Newcastle disease and upper respiratory infection caused by bacteria and virus, no drug residue and no toxic side effect, and farmers can use the pharmaceutical composition without worrying.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicine, and in particular relates to a veterinary antipyretic and detoxification pharmaceutical composition and a preparation method. Background technique [0002] With the intensification and scale of poultry breeding and production in our country, it often causes the prevalence of various infectious diseases, especially colds, fevers, atypical Newcastle disease and upper respiratory tract infections caused by bacteria and viruses clinically. Farmers have brought a lot of trouble. [0003] Poultry influenza is an acute and highly fatal poultry infectious disease caused by avian influenza virus. Symptoms of the disease are that the body temperature rises above 43-44°C, depression, cockscombs and wickers are black, edema occurs in the head, eyelids and wickers are swollen, conjunctiva is inflamed, secretions increase, and breathing is difficult. There are bleeding spots on the oral mucosa an...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/748A61P31/04A61P31/12A61P31/14A61P11/00A61P29/00A61K31/575
Inventor 吴红云李小广卜昌超
Owner ZHENGZHOU HOUYI PHARMA