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Drug combination for treating otitis media and preparation method thereof

A composition and technology for otitis media, which are applied in the directions of drug combinations, pharmaceutical formulations, active ingredients of hydroxyl compounds, etc., to achieve the effect of ensuring stability and avoiding losses

Inactive Publication Date: 2013-01-09
SHENYANG SPORT UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But there is no better ear drops on the market than ofloxacin ear drops

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0039] Example 1 Ear Drops I

[0040]The pharmaceutical composition for the treatment of otitis media of the present invention, preferably raw material drug composition ratio is as follows, all are parts by weight:

[0041] 50 parts of wormwood, 40 parts of gentian, 40 parts of coptis, 30 parts of woody fragrance, 40 parts of garlic, and 1 part of borneol.

[0042] The preparation method of the pharmaceutical composition for the treatment of otitis media of the present invention comprises the following steps

[0043] 1. Material selection:

[0044] 1. Artemisia: This product is the dried whole herb of Incarvilla compacta Maxim. Collected in flowering period, washed the soil, and dried. This product should comply with the relevant provisions of Artemisia annua in the first volume of Tibetan medicine standard (standard number: WS3-BC-0047-95) of the Ministry of Health;

[0045] 2. Gentian: This product is the dried root and rhizome of Gentiana scabra Bunge. This product sho...

Embodiment 2

[0062] Example 2 Ear Drops II

[0063] A kind of pharmaceutical composition for the treatment of otitis media of the present invention, raw material medicine composition ratio is as follows, all are parts by weight:

[0064] 40 parts of wormwood, 50 parts of gentian, 30 parts of coptis, 40 parts of woody fragrance, 30 parts of garlic, and 1.2 parts of borneol.

[0065] The preparation method of the pharmaceutical composition for the treatment of otitis media of the present invention comprises the following steps

[0066] 1. Material selection:

[0067] 1. Artemisia: This product is the dried whole herb of Incarvilla compacta Maxim. Collected in flowering period, washed the soil, and dried. This product should comply with the relevant regulations under the Artemisia annua in the first volume of Tibetan medicine standard of the Ministry of Health (standard number: WS3-BC-0047-95);

[0068] 2. Gentian: This product is the dried root and rhizome of Gentiana manshurica Kitag. ...

Embodiment 3

[0085] Example 3 Ear Drops III

[0086] The pharmaceutical composition for the treatment of otitis media of the present invention, preferably raw material drug composition ratio is as follows, all are parts by weight:

[0087] 60 parts of wormwood, 30 parts of gentian, 50 parts of coptis, 20 parts of woody fragrance, 50 parts of garlic, and 0.8 part of borneol.

[0088] The preparation method of the pharmaceutical composition for the treatment of otitis media of the present invention comprises the following steps

[0089] 1. Material selection:

[0090] 1. Artemisia: This product is the dried whole herb of Incarvilla compacta Maxim. Collected in blooming period, washed the soil, and dried. This product should comply with the relevant regulations under the Artemisia annua in the first volume of Tibetan medicine standard of the Ministry of Health (standard number: WS3-BC-0047-95);

[0091] 2. Gentian: This product is the dried root and rhizome of Gentiana triflora pall, a pl...

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PUM

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Abstract

The invention relates to a drug for treating otitis media. The drug is characterized by consisting of Chinese incarvilla herb, radix gentianae, coptis chinensis, elecampane, garlic, borneol and the like. The drug is a traditional Chinese medicine ear drop prepared from extraction and preparation production and used for treating otitis media. The technical scheme of the invention is as follows: carefully selecting crude drugs; extracting a preparation through a new modernized technique; and setting up a quality detection method of products. The obtained ear drop has a wide range of application and is effective for patients suffering from red and swollen at the initial stage of otitis media without ulcer (aseptic otitis media), suppurative otitis media and various acute and chronic otitis media.

Description

technical field [0001] The invention relates to a pharmaceutical composition and a preparation method thereof, in particular to a pharmaceutical composition for treating otitis media and a preparation method thereof, and belongs to the field of traditional Chinese medicine preparations. Background technique [0002] Otitis externa is mainly caused by bacterial infection (eg, Staphylococcus, Streptococcus, Pseudomonas, Proteus, and Escherichia coli). Typically, low concentrations of bacteria are present in the external auditory canal, the growth of which is mainly inhibited by the weakly acidic pH and the formation of cerumen (earwax). Open wounds left by patients with scraped earwax and epithelium are characterized by a high pH, ​​creating an environment conducive to bacterial infection. Additionally, in patients whose ears are frequently submerged in water, the skin swells and loses its natural acidic environmental protection, increasing the susceptibility of these patient...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61P27/16A61K31/045
Inventor 庞大坤
Owner SHENYANG SPORT UNIV
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