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Pharmaceutical composition capable of strengthening immunity of poultry and method for preparing pharmaceutical composition

A composition and immunity technology, which are applied in the field of pharmaceutical compositions containing natural plant component extracts and their preparation, can solve the problems of increased breeding costs, pollution of livestock products and agricultural environment, and inconspicuous effects, and achieve economical use. The amount and frequency of use, the effect of improving the effect of prevention and treatment, and the effect of prolonging the time of antibody protection

Active Publication Date: 2013-03-06
LUOYANG HUIZHONG ANIMAL MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, the heat stress caused by the high temperature in summer leads to the decline of the immune function of poultry and causes a series of diseases; in addition, in the process of raising broilers, the change of feed, the temperature and humidity of the chicken house and the change of external environmental conditions can sometimes cause metabolic diseases. disorder, affecting its growth rate
For some immunosuppressive diseases, it can reduce the immunity of poultry, increase the incidence rate, make it difficult to treat the disease, and increase the feed-to-meat ratio and feed-to-egg ratio, resulting in difficulty in breeding and raising the cost of breeding, which seriously affects the development of the poultry industry.
At present, immunosuppressive diseases at home and abroad are mainly based on immunoprevention, but it is easy to cause a large stress response during immunization, and if the body's immunity is low, sometimes it will trigger the occurrence of the disease
Studies have proved that plant polysaccharides can regulate the immune function of livestock and poultry, and can improve the immunity of animals, such as astragalus polysaccharides and ganoderma polysaccharides. Although plant polysaccharides have the advantages of being natural and non-toxic and side effects, their effects are slow and the effect is not obvious ; and chemical immune enhancers also have different degrees of disadvantages such as reducing the production performance of livestock and poultry, residual or polluting livestock products and the agricultural environment, and endangering human health.

Method used

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  • Pharmaceutical composition capable of strengthening immunity of poultry and method for preparing pharmaceutical composition
  • Pharmaceutical composition capable of strengthening immunity of poultry and method for preparing pharmaceutical composition
  • Pharmaceutical composition capable of strengthening immunity of poultry and method for preparing pharmaceutical composition

Examples

Experimental program
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Effect test

Embodiment 1

[0037] A preparation method for enhancing poultry immunity is characterized in that it is carried out as follows:

[0038](1) Grind the medicinal material of Astragalus membranaceus into the coarsest powder, add 10 times the amount of water to soak for 1 hour, then reflux extraction 3 times, the amount of water added is 10 times, 8 times, 6 times, and the extraction time is 2 hours, 1.5 hours, After 1.5 hours, combine the three extracts, cool to room temperature, centrifuge in a high-speed centrifuge at 8,000 rpm for 20 minutes, take the supernatant, concentrate to a relative density of 1.15-1.20, add absolute ethanol until the alcohol content is 70 %, stand at 4°C for 12 hours, discard the supernatant, dissolve the precipitate with water, make the concentration 1g crude drug / ml solution, add absolute ethanol until the alcohol content is 35%, centrifuge in a high-speed centrifuge, 8000 rpm Centrifuge for 20 minutes, take the supernatant, add absolute ethanol until the alcohol ...

Embodiment 2

[0042] A method for preparing poultry anti-stress ability and immunity-enhancing medicine, characterized in that it is carried out in the following steps:

[0043] (1) Grind the medicinal material of Astragalus membranaceus into the coarsest powder, add 10 times the amount of water to soak for 1 hour, then reflux extraction 3 times, the amount of water added is 10 times, 8 times, 6 times, and the extraction time is 2 hours, 1.5 hours, After 1.5 hours, combine the three extracts, cool to room temperature, centrifuge in a high-speed centrifuge at 8,000 rpm for 20 minutes, take the supernatant, concentrate to a relative density of 1.15-1.20, add absolute ethanol until the alcohol content is 70 %, stand at 4°C for 12 hours, discard the supernatant, dissolve the precipitate with water, make the concentration 1g crude drug / ml solution, add absolute ethanol until the alcohol content is 35%, centrifuge in a high-speed centrifuge, 8000 rpm Centrifuge for 20 minutes, take the supernatan...

Embodiment 3

[0047] A method for preparing poultry anti-stress ability and immunity-enhancing medicine, characterized in that it is carried out in the following steps:

[0048] (1) Grind the medicinal material of Astragalus membranaceus into the coarsest powder, add 10 times the amount of water to soak for 1 hour, then reflux extraction 3 times, the amount of water added is 10 times, 8 times, 6 times, and the extraction time is 2 hours, 1.5 hours, After 1.5 hours, combine the three extracts, cool to room temperature, centrifuge in a high-speed centrifuge at 8,000 rpm for 20 minutes, take the supernatant, concentrate to a relative density of 1.15-1.20, add absolute ethanol until the alcohol content is 70 %, stand at 4°C for 12 hours, discard the supernatant, dissolve the precipitate with water, make the concentration 1g crude drug / ml solution, add absolute ethanol until the alcohol content is 35%, centrifuge in a high-speed centrifuge, 8000 rpm Centrifuge for 20 minutes, take the supernatan...

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Abstract

The invention provides a pharmaceutical composition capable of strengthening the immunity of poultry. The pharmaceutical composition comprises, by weight, from 5 to 15 parts of butafosfan, from 1 to 10 parts of astragalus polysaccharide and the balance adjuvant materials, and the astragalus polysaccharide is extracted by a method including steps of water boiling backflow and ethanol precipitation. By the pharmaceutical composition, both a cellular immunity level and a humoral immunity level of a poultry organism are obviously improved, particularly, the cellular-level immunity of the poultry organism is strengthened, and accordingly the integral immunity of the poultry organism is effectively strengthened. In addition, by using the pharmaceutical composition with a vaccine, avian antibody titer can be increased, the quantity of generated antibodies is high, the antibodies can be maintained for a long time, and an immunopotentiation effect is obvious. Accordingly, the pharmaceutical composition can be used for cooperative medication for avian Newcastle diseases, bursa of Fabricius, avian influenza and the like, antibody protection time is prolonged, the usage and the usage count of vaccines are reduced, and prevention and treatment effects of the vaccines are improved. The pharmaceutical composition can be used for preventing sudden and serious avian diseases, and accordingly prevalence of common avian diseases is avoided.

Description

technical field [0001] The invention relates to a pharmaceutical composition containing natural plant component extracts and a preparation method thereof, in particular to a pharmaceutical composition containing natural plant component extracts for enhancing poultry immunity and a preparation method thereof. Background technique [0002] In recent years, with the continuous development of my country's poultry industry, the factors hindering the development of poultry industry have become increasingly prominent. For example, the heat stress caused by the high temperature in summer leads to the decline of the immune function of poultry and causes a series of diseases; in addition, in the process of raising broilers, the change of feed, the temperature and humidity of the chicken house and the change of external environmental conditions can sometimes cause metabolic diseases. disorder, affecting its growth rate. For some immunosuppressive diseases, it can reduce the immunity o...

Claims

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Application Information

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IPC IPC(8): A61K31/715A61K31/662A61P37/04
Inventor 张许科刘兴金张晓会
Owner LUOYANG HUIZHONG ANIMAL MEDICINE
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