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Ointment curing newborn red buttock and preparing method of ointment

A technology for newborns and red buttocks, which is applied in the directions of ointment delivery, medical preparations containing active ingredients, and pharmaceutical formulations. , the effect of accelerating healing and improving functional status

Inactive Publication Date: 2014-08-27
NO 1 THE PEOPLES HOSPITAL HUAIAN CITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, among the similar drugs for the treatment of neonatal red buttocks, there may be multiple and complicated side effects on the human body, burying health risks for the baby; or it is inconvenient to use, and the effective therapeutic effect cannot be achieved; or the effect is single, and the scope of use is limited.

Method used

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  • Ointment curing newborn red buttock and preparing method of ointment

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Components in parts by weight of the present invention: comfrey 100g, cod liver oil 15g, tannic acid 30g, glycerin 100g, vaseline 900g.

[0023] Preparation steps of the present invention: according to the above components by weight,

[0024] (1) Fat extraction: Soak comfrey with ethanol, reflux extraction twice, add 10 times the concentration of 70% ethanol for the first time, reflux extraction for 1.5 hours, add 8 times the concentration of filtered medicinal residues to 70% ethanol, reflux for extraction for 1.5 hours, combine the two extracts for later use; the dregs after reflux for later use;

[0025] (2) Add 1 times the weight of 95% ethanol to the tannic acid, heat slowly, and stir gently to melt all the tannic acid, then add the combined extraction solution obtained in step (1) twice, under negative pressure Recover ethanol under the state until there is no alcohol smell, and obtain a liquid containing tannin and comfrey active ingredients, and concentrate the...

Embodiment 2

[0029] Components in parts by weight of the present invention: 200 g of comfrey, 100 g of cod liver oil, 100 g of tannic acid, 150 g of glycerin, and 1000 g of petrolatum.

[0030] Preparation steps of the present invention: according to the above components by weight,

[0031] (1) Fat extraction: Soak comfrey with ethanol, reflux extraction twice, add 10 times the concentration of 80% ethanol for the first time, reflux extraction for 2 hours, add 8 times the concentration of the filtered medicinal residue to 80% ethanol, reflux for extraction for 2 hours, combine the two extracts for later use; the dregs after reflux for later use;

[0032] (2) Add 1 times the weight of 95% ethanol to the tannic acid, heat slowly, and stir gently to melt all the tannic acid, then add the combined extraction solution obtained in step (1) twice, under negative pressure Recover ethanol under the state until there is no alcohol smell, and obtain a liquid containing tannic acid and comfrey active...

Embodiment 3

[0036] Components in parts by weight of the present invention: 250 g of comfrey, 200 g of cod liver oil, 150 g of tannic acid, 200 g of glycerin, and 1100 g of petrolatum.

[0037] Preparation steps of the present invention: according to the above components by weight,

[0038] (1) Lipid extraction: Soak comfrey with ethanol, reflux extraction twice, add 10 times the concentration of 85% ethanol for the first time, reflux extraction for 2.5 hours, add 8 times the concentration of filtered medicinal residues to 85% ethanol, reflux for extraction for 2.5 hours, combine the two extracts for later use; the dregs after reflux for later use;

[0039] (2) Add 1 times the weight of 95% ethanol to the tannic acid, heat slowly, and stir gently to melt all the tannic acid, then add the combined extraction solution obtained in step (1) twice, under negative pressure Recover ethanol under the condition until there is no alcohol smell, and obtain a liquid containing tannin and comfrey acti...

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Abstract

The invention discloses ointment curing newborn red buttock and a preparing method of the ointment. The ointment comprises the following components by weight: 100 to 250 parts of arnebia root, 15 to 200 parts of fish liver oil, 30 to 150 parts of tannic acid, 20 to 200 parts of glycerol, and 900 to 1100 parts of vaseline. The method comprises the following steps: taking arnebia root according to the proportion of the recipe; extracting effective components of arnebia root through fat extraction and water extraction; adding tannic acid, glycerol, fish liver oil and vaseline according to the proportion of the recipe into the effective components; stirring uniformly; and obtaining ointment curing newborn red buttock through an emulsion homogenization mechanism. The ointment is simple in recipe, good in curative effect, low in price and convenient for use, and has a better curing effect for skin mucosal diseases such as anal fissure, scalding and bedsore.

Description

technical field [0001] The invention relates to the field of drugs for treating red buttocks of newborns, in particular to a Chinese patent medicine ointment for treating red buttocks of newborns and a preparation method thereof, which can also improve anal fissures, scalds, bedsores and other difficult-to-treat skin and mucous membrane diseases. Background technique [0002] Neonatal red buttocks (also known as diaper dermatitis) is caused by long-term contact between wet diapers and skin; use of diapers that are not rinsed clean and leave residual soap; often use plastic or rubber pads; fatty acid and alkaline substances stimulate the skin during diarrhea. Causes inflammatory changes in the skin of the diaper-covered area. Newborns have thin skin and are usually swaddled, so they are prone to red buttocks. At present, among the similar drugs for the treatment of red buttocks in newborns, they may have multiple and complicated side effects on the human body, burying health...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/30A61K9/06A61P17/00A61P17/02A61P1/00
Inventor 王国如梁茂本孔苏南朱月梅曹正雨
Owner NO 1 THE PEOPLES HOSPITAL HUAIAN CITY
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