Catalyst for synthesizing isobutyrophenone by isobutyric acid and methyl benzoate and applications thereof

Abstract

The invention discloses a catalyst for synthesizing isobutyrophenone by isobutyric acid and methyl benzoate and applications thereof, wherein the catalyst comprises active components, carriers and additive agents; the active components are selected from one or multiple of rear earth oxides; the carriers are selected from one or multiple of SiO2, Al2O3 or ZnO; the additive agents are selected from one or multiple of alkaline earth metal oxides; each component content is calculated by weight percent; the content of the active components is 5-50wt%; the content of the carriers is 50-95wt%; and the content of the additive agents is 0.5-5wt% of the total weight of the active components and the carriers. The catalyst provided by the invention is used for synthesizing isobutyrophenone by isobutyric acid and methyl benzoate, improves the technology process for preparing isobutyrophenone, is simple to operate, can be produced continuously, improves the production efficiency, lowers the energy consumption, and alleviates pollution.

Description

technical field [0001] The invention belongs to the field of catalysts for fine chemical products, in particular to a catalyst for synthesizing isobutyrophenone from isobutyric acid and methyl benzoate and an application thereof. Background technique [0002] Isobutyrophenone, also known as isopropyl phenyl ketone or acetobutyl ketone, is a colorless transparent liquid at room temperature. It is mainly used as an intermediate of photoinitiator 1173 (chemical name is 2-methyl-1-phenyl-2-hydroxyacetone) in photocurable coatings. As a new generation of photoinitiator, it has ultraviolet absorption range Wide, long storage life, no yellowing and other advantages, broad application prospects. It can also be used in other organic synthesis, such as substitution, addition, condensation, oxidation, reduction, etc., for example: isobutyrophenone can be used to synthesize p-chloroisobutyrophenone, a pesticide intermediate, etc. [0003] The synthesis of isobutyrophenone is generally...

AI Technical Summary

Problems solved by technology

However, there are many defects in this synthetic route: the process route is long, the cost is high, the operation is complicated, and it can only be operated intermittently, and continuous production cannot be realized; the acylation substitution reaction needs to be carried out under anhydrous conditions, and isobutyryl chloride and the catalyst trichloro Aluminum is corrosive and has high requirements on reaction conditions and equipment; reaction raw materials and intermediates are highly toxic and irritating; a lot of waste lye and waste water are produced in the post-treatment process, causing serious pollution

And benzoic acid is the higher solid of fusing point, with it as reaction raw material, is not convenient to continuous feed to fixed-bed reactor

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