Yufengningxin (medicine name) soft capsule and preparation method thereof

A soft-heart and capsule technology, applied in the field of Yufeng Ningxin soft capsule and its preparation, achieves the effects of ensuring stability, simple operation, and reducing types and dosages

Active Publication Date: 2015-06-10
CHENGDU RUNHUATANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] In the prior art, there is no report about Yufeng Ningxin Soft Capsules with simple compatibility, simple preparation process, better content stability and fluidity

Method used

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  • Yufengningxin (medicine name) soft capsule and preparation method thereof
  • Yufengningxin (medicine name) soft capsule and preparation method thereof
  • Yufengningxin (medicine name) soft capsule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Preparation of kudzu root extract:

[0024] According to the existing Yufeng Ningxin Granules, the Pueraria lobata medicinal material is crushed, alcohol extracted, and the alcohol extraction product is concentrated and dried. The alcohol extraction uses 85% ethanol that is 10 times the weight of the Pueraria lobata medicinal material as the extraction solvent. The degree of extraction, extraction solvent, extraction times and extraction time, concentration method, relative density of clear paste and thick paste, etc. all refer to the existing preparation process of Yufeng Ningxin Granules.

[0025] Then use a vacuum drying oven to dry under reduced pressure, the drying temperature is 60°C, the vacuum degree is -0.08~-0.09Mpa, and it is crushed into fine powder after drying.

[0026] The main components of the 85% ethanol extract of Pueraria lobata root are isoflavones such as puerarin, and these components are insoluble in soybean salad oil. Therefore, the soft capsule...

Embodiment 2

[0028] Take the extract powder, add soybean salad oil and beeswax, heat up to about 35°C to melt the beeswax, stir evenly, fill it with a soft capsule machine, and obtain it. The weight ratio of the extract powder to the salad oil is 2.5:2, and the beeswax weight accounts for 1% of the salad oil weight.

Embodiment 3

[0030] Repeat embodiment 2 steps, difference is: the weight ratio of extract powder and salad oil is 3.5:2, and beeswax weight accounts for 2% of salad oil weight.

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Abstract

The invention provides a yufengningxin (medicine name) soft capsule which comprises a radix puerariae extract, salad oil and bee wax, wherein the weight ratio of the radix puerariae extract to the salad oil is (2.5-3.5) to 2; and the bee wax accounts for 1-2% of the weight of the salad oil. By optimizing the usage amounts of the bee wax and the salad oil, the materials are mixed, heated and stirred to obtain homogenized disperse transparent content, macroscopic suspension particles or deposits are inexistent in the content, effective ingredients are uniformly distributed, the stability is lasting, and the absorption and treatment effects are excellent after the soft capsule is taken. The invention further provides a preparation method of the soft capsule, and the preparation method is simple to operate, moderate in reaction conditions, easy to implement and low in process cost.

Description

technical field [0001] The invention relates to a soft capsule, in particular to a Yufeng Ningxin soft capsule and a preparation method thereof. Background technique [0002] Yufeng Ningxin Granules are recorded on pages 145-146 of the "National Standard Compilation of Chinese Patent Medicines, Brain System, Meridians and Limbs" [1] (Standard No. WS-10622 (ZD-0622)-2002), which can relieve spasm and relieve pain, strengthen the brain And coronary blood flow, attending high blood pressure dizziness, headache, neck pain, coronary heart disease, angina pectoris, nervous headache, early sudden deafness embolism. It has been used clinically for many years and has a remarkable effect. [0003] Yufeng Ningxin granule is made by crushing kudzu root into coarse powder, extracting three times with 80~90% ethanol under reflux, four hours for the first time, three hours for the second and three times, filtering, combining the filtrates, recovering the ethanol and depressurizing Concen...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61K36/488A61K47/44A61P9/10A61P29/00A61P9/12A61P25/00A61P27/16
Inventor 牛锐
Owner CHENGDU RUNHUATANG PHARMA
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