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Natural pharmaceutical composition

A technology of natural medicines and compositions, applied in drug combinations, antitumor drugs, pharmaceutical formulations, etc.

Inactive Publication Date: 2013-09-25
石强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Natural pharmaceutical composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment approach

[0031] The first step: preparation of various extracts

[0032] (1) Preparation of psyllium cinnamon decoction concentrated extract

[0033] Take plantain seed and cinnamon according to the compatibility ratio of 1-4:1, soak in 10 times the amount of distilled water, heat and decoct, filter with silk cloth, add distilled water to the medicinal residue, soak, decoct, and filter in the same way, and combine the two filtrates, Concentrate by heating, filter with ultrafiltration membrane, and dry under reduced pressure at 70°C.

[0034] (2) Preparation of psyllium polysaccharide

[0035] Take Plantaginaceae, extract with NaOH solution with pH=9, filter the extract, adjust the filtrate to neutral with dilute hydrochloric acid, concentrate the solution, let it cool, add 2 times the amount of ethanol under stirring and let it stand for 8 hours, filter the ethanol, Soak in absolute ethanol for 1 hour and dry in an oven at 60°C.

[0036] (3) Preparation of cinnamaldehyde

[0037] C...

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Abstract

The invention relates to a natural pharmaceutical composition, which is prepared from semen plantaginis and cinnamon decocted and concentrated extract, semen plantaginis polysaccharide and cinnamyl aldehyde in a ratio of (2-7):(3-9):(1-4). The composition has a good curative effect for diarrhea related to cancer chemotherapy and has certain synergism on cancer chemotherapy.

Description

technical field [0001] The present invention relates to a kind of natural medicine composition, more specifically relate to a kind of natural medicine composition that is composed of plantago cinnamon decoction concentrated extract, plantago polysaccharide and cinnamaldehyde, the preparation method of the natural medicine composition and Use of the natural medicine composition for preparing medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs, whether used alone or in combination, can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called chemotherapy-associated ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/68A61P35/00A61P1/12A61K31/715A61K31/11
Inventor 石强
Owner 石强