Preparation method of diammonium glycyrrhizinate lipid compound effervescent granule
A technology of diammonium glycyrrhizinate lipid and diammonium glycyrrhizinate, which is applied in the field of preparation of diammonium glycyrrhizinate lipid complex effervescent granules, can solve the problem of poor liver protection and enzyme reduction effect, difficulty in taking, and incomplete dissolution To achieve the effect of improving drug absorption, improving bioavailability, and protecting liver cell membranes
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
Method used
Examples
Embodiment 1
[0036] The first step, pretreatment of raw materials:
[0037] 1, diammonium glycyrrhizinate is made into diammonium glycyrrhizinate lipid complex;
[0038] 1) Diammonium glycyrrhizinate is made into diammonium glycyrrhizinate extract:
[0039] ①Add 100 parts of diammonium glycyrrhizinate and 700 parts of ethanol aqueous solution (80-85% purity) into the container, and heat it in a water bath at 95°C until it dissolves;
[0040] ②Let the above solution stand for a while, then pour the supernatant into another container to cool and let it stand for 10 hours, and obtain crystals by suction filtration;
[0041] ③Add the above crystals and 500 parts of ethanol aqueous solution (80-85% purity) into the container, and heat in a water bath at 95°C until dissolved;
[0042] ④Repeat step ②, and then dry the crystals to a state without ethanol smell;
[0043] ⑤ Dry the above-mentioned crystals in an environment above 55°C for more than 24 hours to obtain a purified diammonium glycyrr...
Embodiment 2
[0062] The first step, pretreatment of raw materials:
[0063]1, diammonium glycyrrhizinate is made into diammonium glycyrrhizinate lipid complex;
[0064] 1) Diammonium glycyrrhizinate is made into diammonium glycyrrhizinate extract:
[0065] ① Add 100 parts of diammonium glycyrrhizinate and 800 parts of ethanol aqueous solution (purity 80-85%) into the container, and heat it in a water bath at 100°C until it dissolves;
[0066] ②Let the above solution stand for a while, then pour the supernatant into another container to cool and stand for 12 hours, and obtain crystals by suction filtration;
[0067] ③ Add the above crystals and 600 parts of ethanol aqueous solution (80-85% purity) into the container, and heat in a water bath at 100°C until dissolved;
[0068] ④Repeat step ②, and then dry the crystals to a state without ethanol smell;
[0069] ⑤ Dry the above-mentioned crystals in an environment above 55°C for more than 24 hours to obtain a purified diammonium glycyrrhizi...
Embodiment 3
[0088] The first step, pretreatment of raw materials:
[0089] 1, diammonium glycyrrhizinate is made into diammonium glycyrrhizinate lipid complex;
[0090] 1) Diammonium glycyrrhizinate is made into diammonium glycyrrhizinate extract:
[0091] ①Add 100 parts of diammonium glycyrrhizinate and 900 parts of ethanol aqueous solution (80-85% purity) into the container, and heat it in a water bath at 105°C until it dissolves;
[0092] ②Let the above solution stand for a while, then pour the supernatant into another container to cool and stand for 14 hours, and obtain crystals by suction filtration;
[0093] ③Add the above crystals and 700 parts of ethanol aqueous solution (80-85% purity) into the container, and heat in a water bath at 105°C until dissolved;
[0094] ④Repeat step ②, and then dry the crystals to a state without ethanol smell;
[0095] ⑤ Dry the above-mentioned crystals in an environment above 55°C for more than 24 hours to obtain a purified diammonium glycyrrhizin...
PUM
Login to View More Abstract
Description
Claims
Application Information
Login to View More