Novel ferrous fumarate and folic acid compound capsule

Abstract

The invention relates to an oral hard capsule, and particularly relates to a tablet capsule filled with ferrous fumarate tablets and folic acid tablets. The tablet capsule comprises a capsule body and tablets therein, wherein the capsule body comprises an upper capsule body and a lower capsule body and filled with at least one tablet of which the active component is the ferrous fumarate and at least one tablet of which the active component is the folic acid. Because the active components in the capsule body do not contact with each other, the active components cannot be chemically compatible with each other to generate byproducts, the tablet capsule can be more stable, and especially degradation products generated after the contact of the ferrous fumarate and the folic acid are reduced. In addition, due to the adoption of the cylindrical tablets, the design of different colors and the application of the transparent capsule body, the tablet capsule is very suitable for industrial production, and the compliance of a patient can be improved. Moreover, because the tablets are respectively prepared from the active components, the quality of the tablet capsule is easier to test and control.

Description

technical field [0001] The invention relates to an oral hard capsule, in particular to a tablet capsule filled with folic acid tablets and ferrous fumarate tablets. Background technique [0002] Iron is one of the essential trace elements for the human body. It is directly involved in the production of hemoglobin. Iron supplementation can help reduce the risk of iron deficiency anemia; folic acid, vitamin B12 and vitamin C participate in the production of red blood cells and hemoglobin. Supplementing folic acid can help blood health , It can also promote the production of immunoglobulin, which helps to improve the nervous system. Products that supplement iron and folic acid at the same time include two categories, one is health care products, such as Nutrilite iron folic acid tablets, etc.; the other is medicine, such as UCB's pregaday. [0003] At present, there is no dosage form in which ferrous fumarate and folic acid are present in the same preparation and the active in...

AI Technical Summary

Problems solved by technology

If the active ingredients are in contact with each other, there are the following disadvantages: 1. Due to the influence of multi-component mixing uniformity, it is difficult to quantify each component accurately; 2. During product testing, it is difficult to determine the content of each component due to mutual interference, which affects the qualitative and quantitative analysis results; 3. . During long-term storage, due to possible chemical compatibility changes among the components, by-products are likely to be produced, reducing the effect or increasing side effects, and the product stability is not ideal.

Images