Method for preparing electrochemical sensors for detecting vitamins B in plasma of human body based on gold nanoparticle modified electrode

Abstract

The invention relates to a method for preparing electrochemical sensors, and particularly relates to the preparation of novel electrodes based on gold nanoparticles. In a sensor provided by the invention, due to the modification of the gold nanoparticles, the surface area and porosity of an electrode are greatly increased, and an electrochemical detection method based on the gold nanoparticle modified carbon paste electrode provides a novel, simple, good-selectivity and quickly-responded method for detecting vitamins B in plasma of a human body. The invention provides a reliable, simple, rapid, selective and high-sensitivity method for detecting vitamins B by using the square wave voltammetry.

Description

Technical field: [0001] The invention relates to a preparation method of an electrochemical sensor, in particular to a preparation of a novel electrode based on gold nanoparticle. Background technique: [0002] Vitamin B (FA, (2S)-2-[(4-{[(2-amino-4-hydroxypterin-6-alkyl)methyl]amino}phenyl)carbamoxime]glutaric acid), also Called folic acid, vitamin M is essential for bodily functions. The human body needs B vitamins to synthesize DNA, repair RNA, for DNA methylation, and as a cofactor for certain biological reactions. Vitamin B 9 (Folic acid) is found naturally in many foods such as broccoli, cabbage, fruits and nuts. Folate is added to legumes in many countries. In these countries, food supplemented with folic acid is an important way for humans to absorb folic acid. [0003] The detection of FA in pharmaceuticals, clinical diagnostics, and food has attracted great attention because FA deficiency is strongly associated with neonatal neural tube defects and increases t...

AI Technical Summary

Problems solved by technology

While these methods have some sensitivity and accuracy, they are all expensive, complex and time-consuming