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Non-woven fabric containing bone prosthetic material

A non-woven fabric and fiber technology, applied in bone implants, medical science, tissue regeneration, etc., can solve the problems of long time required for alveolar bone regeneration, leakage of affected parts, and inability of cells to infiltrate, so as to improve bone regeneration Efficiency, increase in proliferation efficiency, and the effect of improving proliferation ability

Inactive Publication Date: 2013-11-20
SUNSTAR KK
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, currently used bone filling materials have insufficient cell adhesion and proliferation, and it takes a long time for alveolar bone regeneration
In addition, the adhesiveness to the alveolar bone and the indwelling ability to the affected area cannot be said to be good, and even if it is embedded with GBR membrane, it may leak from the affected area.
[0005] In addition, there are also cases where bone cement is used, but there is a disadvantage that cells cannot infiltrate into the bone cement
[0006] As mentioned above, currently used bone regeneration materials have problems of insufficient cell adhesion and proliferation

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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  • Non-woven fabric containing bone prosthetic material
  • Non-woven fabric containing bone prosthetic material
  • Non-woven fabric containing bone prosthetic material

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Experimental program
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Embodiment

[0117] Hereinafter, although this invention is demonstrated concretely, this invention is not limited to the following example. In addition, it is possible to appropriately refer to a textbook or the like in the technical field (for example, Molecular Cloning: A Laboratory Manual (3 Vol. Set); Cold Spring Harbor Laboratory Press) in the experiment.

[0118] Manufacturing of non-woven fabrics 1

[0119] Add 43g of a mixed solution of hexafluoroisopropanol:dichloromethane=8:2 (mass ratio) to 7g of polylactic acid (Mitsui Chemicals, LACEA, H-400) to dissolve it to obtain a polylactic acid solution (14w / w %). The polylactic acid solution was filled into a syringe (Henke SASS WOLF, 5 ml), a needle (Terumo, Non-bevel needle 21G1.1 / 2) was installed in the syringe and then set in an electrospinning device. The distance between the syringe and the target ground electrode was set at 8 cm, and spraying was carried out by changing the spray amount and spray time under the conditions s...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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Abstract

An object of the present invention is to provide a bone regeneration material suitable for bone (in particular, alveolar bone) regeneration. The present invention provides a non-woven fabric containing a bone prosthetic material wherein the bone prosthetic material is included between biocompatible fibers that constitute the non-woven fabric. The non-woven fabric may be suitably used as a bone regeneration material (in particular, a dental bone regeneration material).

Description

technical field [0001] The present invention relates to non-woven fabrics containing bone filling materials. Background technique [0002] In recent years, in the case of tooth loss due to aging or periodontal disease, etc., artificial tooth roots are embedded in the alveolar bone, artificial crowns and superstructures are installed on them (so-called "implant treatment"). "). [0003] If the tooth is missing (i.e. if a tooth is lost), the alveolar bone supporting the tooth is rapidly resorbed and reduced. Therefore, in the implant treatment, the thickness of the alveolar bone is often insufficient when the artificial tooth root is embedded in the alveolar bone. If the thickness of the alveolar bone is insufficient, even if the artificial tooth root is embedded, there is a great concern about instability. In such a case, treatment such as bone grafting or bone regeneration is taken. [0004] For example, one of the methods frequently used for alveolar bone regeneration i...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L27/00
CPCA61L27/36A61L27/46A61L2430/02A61F2/28A61L27/00A61L27/14
Inventor 兴村祐介喜多一吉花木尚幸根本泰典
Owner SUNSTAR KK
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