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Traditional Chinese medicine capsule preparation for treating lumbar disc herniation and preparation method of traditional Chinese medicine capsule preparation

A technology of herniated lumbar intervertebral discs and traditional Chinese medicine capsules, which is applied in capsule delivery, pharmaceutical formulas, non-central analgesics, etc., can solve problems such as unsatisfactory treatment effects, and is beneficial to the recovery of motor function and muscle strength and reduces inflammation. , Shorten the effect of nerve regeneration and repair process

Inactive Publication Date: 2015-03-25
山西师范大学
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The present invention provides a traditional Chinese medicine capsule preparation for treating lumbar intervertebral disc herniation in order to solve the problem of unsatisfactory therapeutic effect of traditional Chinese medicine for treating lumbar intervertebral disc herniation

Method used

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  • Traditional Chinese medicine capsule preparation for treating lumbar disc herniation and preparation method of traditional Chinese medicine capsule preparation

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] A traditional Chinese medicine capsule preparation for treating lumbar intervertebral disc herniation. 20 parts of Achyranthes bidentata, 25 parts of Uncaria vine, 20 parts of angelica, 15 parts of safflower, 15 parts of Wujiapi, 15 parts of Shenjincao, 20 parts of Eucommia, 20 parts of cassia twig, 20 parts of frankincense, 10 parts of ground beetle, licorice 20 servings.

[0070] The preparation method of above-mentioned capsule preparation is as follows:

[0071] (1) Weigh each API according to the ratio of parts by mass;

[0072] (2) Crumble the above-mentioned crude drug into 20-mesh coarse powder, soak in 5 times the amount of 60% ethanol for 18 hours, heat and reflux for 3 hours, and collect the extract once;

[0073] (3), add 2 times the amount of 55% ethanol and heat to reflux for 2 hours, and collect the secondary extract;

[0074] (4) Combine the above secondary extracts and filter, add ZTC-Ι natural clarifier at 0.2% to the filtrate, stir well, filter, co...

Embodiment 2

[0077] A traditional Chinese medicine capsule preparation for treating lumbar intervertebral disc herniation. 15 parts of Achyranthes bidentata, 30 parts of Uncaria vine, 18 parts of angelica, 20 parts of safflower, 18 parts of Wujiapi, 18 parts of Shenjincao, 23 parts of Eucommia, 18 parts of cassia twig, 18 parts of frankincense, 6 parts of ground beetle, licorice 12 servings.

[0078] The preparation method of above-mentioned capsule preparation is as follows:

[0079] (1) Weigh each API according to the ratio of parts by mass;

[0080] (2) Crumble the above-mentioned crude drug into 40-mesh coarse powder, soak in 4 times the amount of 50% ethanol for 12 hours, heat and reflux for 2 hours, and collect the extract once;

[0081] (3) Add 4 times the amount of 70% ethanol and heat to reflux for 3 hours to collect the secondary extract;

[0082] (4) Combine the above secondary extracts and filter, add ZTC-Ⅲ natural clarifier to the filtrate at a rate of 0.1%, fully stir and ...

Embodiment 3

[0085] A traditional Chinese medicine capsule preparation for treating lumbar intervertebral disc herniation. 24 parts of Achyranthes bidentata, 20 parts of Uncaria vine, 25 parts of angelica, 10 parts of safflower, 10 parts of Wujiapi, 12 parts of Shenjincao, 25 parts of Eucommia, 25 parts of cassia twig, 15 parts of frankincense, 5 parts of ground beetle, licorice 30 servings.

[0086] The preparation method of above-mentioned capsule preparation is as follows:

[0087] (1) Weigh each API according to the ratio of parts by mass;

[0088] (2) Crumble the above-mentioned crude drug into 25-mesh coarse powder, soak in 6 times the amount of 70% ethanol for 16 hours, heat and reflux for 3 hours, and collect the extract once;

[0089] (3) Add 3 times the amount of 60% ethanol and heat to reflux for 2 hours to collect the secondary extract;

[0090](4) Combine the above secondary extracts and filter, add ZTC-II natural clarifier and 0.3% ZTC-IV natural clarifier to the filtrate ...

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Abstract

The invention belongs to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine capsule preparation for treating lumbar intervertebral disc herniation and a preparation method thereof. The technical scheme adopted is: will be composed of dog ridge, Alisma, gallinaceae, Poria cocos, Achyranthes bidentata, Uncaria, angelica, safflower, acanthopanax bark, Shenjincao, Eucommia ulmoides, cassia twig, frankincense, ground beetle and licorice The composed raw materials are pulverized according to the stated mass ratio, soaked in ethanol solution, heated to reflux twice, and filtered to collect the extract, add the sedimentation agent to the extract, stir fully, filter, concentrate into a fluid extract, and dry Grinding into powder, adding dispersant and other auxiliary materials in proportion, filling and preparing into capsules. The capsule preparation obtained by the present invention has the effects of promoting blood circulation and diuresis, activating menstruation and collaterals, anti-inflammation and analgesia, nourishing the liver and strengthening the kidney, repairing the annulus fibrosus and improving microcirculation, thereby promoting the reduction of the nucleus pulposus, reducing nerve root compression and aseptic inflammation, and promoting Restoring damaged nerves, relieving and eliminating symptoms of low back and leg pain.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine and its preparation, in particular to a traditional Chinese medicine capsule preparation for treating lumbar intervertebral disc herniation and a preparation method thereof. Background technique [0002] Lumbar intervertebral disc herniation, also known as herniated nucleus pulposus, or lumbar disc annulus fibrosus rupture, is one of the most common clinical orthopedic diseases, and it is difficult to recover. This disease is mainly due to the nucleus pulposus, annulus fibrosus and After the cartilage has degenerative changes to varying degrees, under the action of external force, the fibrous annulus of the intervertebral disc ruptures, and the nucleus pulposus tissue protrudes from the rupture, causing stimulation or compression of spinal nerve roots, spinal cord and other adjacent tissues, resulting in low back and leg pain Symptoms such as acidity, sinking, swelling, numbne...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/48A61P19/08A61P29/00A61K35/64A61K36/884
Inventor 杜黎明秦宝兰尤俊臣杜谦张利珍郭小慧
Owner 山西师范大学