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Xiangmahanchuantie (XMHCT) and preparation technology

A technology of sesame and clove, applied in the field of medicine, can solve the problems of increasing the risk of cataract and glaucoma, suppressing adrenal cortex function, and limiting the scope of application, etc., and achieves the effect of single use, simple preparation, and broad application prospects

Inactive Publication Date: 2013-12-18
XIANGYU PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The two-pronged approach of anti-asthma and anti-allergic inflammatory drugs is used to achieve rapid and long-lasting curative effect. However, asthmatic patients who use glucocorticoids for a long time will bring more serious side effects. The currently known side effects include easy ecchymosis (because subcutaneous tissue thinning), adrenal suppression, decreased bone density, and increased risk of cataracts and glaucoma
Based on the shortcomings brought about by the above-mentioned western medicines, at present, more Chinese herbal medicine technologies have been studied, such as preparing Chinese herbal medicines into patches or oral powders, etc. Among them, CN200910227111 prepared a kind of patch for treating asthma in children, and achieved certain therapeutic effect. effect, but the patch is only for mild patients, and it needs to be treated with western medicine, which causes a burden of medication for children, and the scope of application is greatly limited

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A kind of plaster (Xiang Ma Han Chuan plaster) for the treatment of children's asthma, it is prepared by following crude drug: clove 100g, ephedra 95g, Bupleurum 85g, burdock root 80g, kudzu root 70g, safflower 65g, bellflower 60g, Pinellia 55g, Pseudostellaria 50g, mulberry leaves 45g, licorice 40g, Fritillaria 35g, pepper 30g, mountain bean root 20g, cicada slough 10g, earthworm 10g.

[0020] Its preparation method comprises the following steps:

[0021] 1) Weigh 100g of cloves, 95g of ephedra, 85g of Bupleurum, 65g of safflower, 40g of licorice, 35g of Chuan Fritillaria and 30g of pepper, mix well, add 5 times the weight of water and cook for 1 hour, filter and collect the filtrate, and then put the filtrate Concentrated into an extract whose density is 1.1g / m1;

[0022] 2) Weigh 70g of kudzu root, 55g of pinellia, 50g of heterophylla and 45g of mulberry leaves, put them into a pulverizer and grind them, take out the powder and spread it into a thickness of 1cm, and...

Embodiment 2

[0028] 1. Animal safety test:

[0029] 1 times, 5 times and 10 times of the paste amount were respectively pasted on the back of the depilated rabbits for 24 hours each time, once a day for 10 consecutive days. The blood picture, lung, liver, and kidney functions were observed, and no toxic effect was found; no toxic damage was found in the heart, liver, spleen, lung, kidney and other organs through pathological sections. It can be seen that the patch of the present invention is safe, reliable and has no toxic and side effects.

[0030] 2. Clinical trials:

[0031] 1) Asthma diagnostic criteria:

[0032] 1. Recurrent episodes of wheezing, shortness of breath, chest tightness or cough are mostly related to exposure to allergens, cold air, physical and chemical stimuli, viral upper respiratory tract infections, exercise, etc.; Diffuse wheezing mainly in the expiratory phase, with protracted expiratory phase; 3. The above symptoms and signs can be relieved by treatment or reli...

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PUM

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Abstract

The invention belongs to the field of medical technology, and discloses xiangmahanchuantie (XMHCT). The XMHACT is prepared from flos caryophyllata, ephedra herb, radix bupleuri, burdock root, radix puerariae, safflower, radix platycodonis, rhizoma pinelliae, radix pseudostellariae, mulberry leaf, liquorice, bulbus fritillariae cirrhosae, pepper, radix sophorae tonkinensis, periostracum cicadae, earthworm and the like. The invention further discloses a preparation method of the XMHACT. The XMHACT prepared is capable of treating both manifestation and root causes of diseases, has no side effects, can be separately used and has good treatment effect on pediatric asthma.

Description

technical field [0001] The invention belongs to the technical field of medicine, and relates to a patch for treating children with asthma, in particular to a Xiangma Hanchuan patch and a preparation process thereof. Background technique [0002] Bronchial asthma is one of the most common chronic respiratory diseases among children. The prevalence varies greatly in different regions and races. It is usually higher in developed countries than in developing countries, and higher in cities than in rural areas. The prevalence of asthma in children varies from 0-30%. The prevalence of asthma is on the rise worldwide. According to the 1998 survey by the International Children's Asthma and Allergy Research (ISAAC) group, the incidence of asthma in British school-age children rose from 10.2% in 1989 to 20.9% in 1996. . The prevalence of asthma in children under the age of 17 in the United States increased from 3.2% to 4.3% in the 1980s, and reached 5.7% in 1997. According to the s...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8966A61K9/70A61P11/06A61K35/64A61K35/56A61K35/62
Inventor 林凡友林凡儒
Owner XIANGYU PHARMA
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