Medicinal composition for treating turtle cavity disease and preparation method thereof

A composition and drug technology, applied in the direction of medical formula, medical preparations containing active ingredients, antibacterial drugs, etc., to achieve strong anti-virus, simple and easy preparation method, suitable for large-scale production

Inactive Publication Date: 2013-12-25
XINGHUA HENGWEI BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Distributed in Japan and the south of mainland China and other places, it grows at an altitude of

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] A medicinal composition for treating soft-shelled turtle hole disease, comprising the following traditional Chinese medicines in parts by weight: 15 parts of Hedyotis diffusa, 20 parts of Senecio, 5 parts of Galla chinensis, 10 parts of Cortex Phellodendri, 2 parts of wild chrysanthemum, and 5 parts of onion share.

[0022] The preparation method of described pharmaceutical composition comprises the following steps:

[0023] 1) Hedyotis diffusa weighed according to the above parts by weight plus 80% ethanol in an amount 10 times its weight, using supercritical CO 2 The active ingredients of Hedyotis diffusa are extracted;

[0024] 2) Weigh Senecio according to the above parts by weight and add 75% ethanol which is 10 times of its weight to carry out ethanol reflux extraction, extract 5 times, each time for 2.5h to obtain the active ingredients of Senecio;

[0025] 3) Weigh gallnut, Phellodendron, wild chrysanthemum, and onion according to the above parts by weight, ad...

Embodiment 2

[0031] A pharmaceutical composition for treating soft-shelled turtle hole disease, comprising the following traditional Chinese medicines in parts by weight: 30 parts of Hedyotis diffusa, 30 parts of Senecio, 15 parts of Galla chinensis, 25 parts of Cortex Phellodendri, 10 parts of wild chrysanthemum, and 15 parts of onion share.

[0032] The preparation method of described pharmaceutical composition comprises the following steps:

[0033] 1) Hedyotis diffusa weighed according to the above parts by weight plus 80% ethanol in an amount 15 times its weight, using supercritical CO 2 The active ingredients of Hedyotis diffusa are extracted;

[0034] 2) Weigh Senecio according to the above parts by weight and add 75% ethanol which is 15 times its weight to carry out ethanol reflux extraction, extract 5 times, each time for 2.5h to obtain the active ingredients of Senecio;

[0035] 3) Weigh gallnut, Phellodendron, wild chrysanthemum, and onion according to the above parts by weigh...

Embodiment 3

[0041] A pharmaceutical composition for treating soft-shelled turtle hole disease, comprising the following traditional Chinese medicines in parts by weight: 20 parts of Hedyotis diffusa, 25 parts of Senecio, 10 parts of Galla chinensis, 20 parts of Cortex Phellodendri, 7 parts of wild chrysanthemum, and 10 parts of onion share.

[0042] The preparation method of described pharmaceutical composition comprises the following steps:

[0043] 1) Hedyotis diffusa weighed according to the above parts by weight plus 80% ethanol in an amount 12 times its weight, using supercritical CO 2 The active ingredients of Hedyotis diffusa are extracted;

[0044] 2) Weigh Senecio according to the above parts by weight and add 13 times its weight of 75% ethanol to carry out ethanol reflux extraction, extract 5 times, each time for 2.5h to obtain the active ingredients of Senecio;

[0045] 3) Weigh gallnut, Phellodendron, wild chrysanthemum, and onion according to the above parts by weight, add ...

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PUM

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Abstract

The invention discloses a medicinal composition for treating a turtle cavity disease. The medicinal composition for treating the turtle cavity disease comprises the following Chinese herbs in parts by weight: 15-30 parts of hedyotis diffusa, 20-30 parts of groundsel, 5-15 parts of gallnut, 10-25 parts of golden cypress, 2-10 parts of wild chrysanthemum flower and 5-15 parts of onion. The invention further discloses a preparation of the medicinal composition. The hedyotis diffusa and the groundsel have a very strong anti-virus effect, so that the hedyotis diffusa and the groundsel as effective components can prevent and treat the turtle cavity disease better, with the cure rate as high as 99%. In the preparation method, the hedyotis diffusa is extracted with a supercritical carbon dioxide extraction method, so that effective components of the hedyotis diffusa, namely hentriacontane, stigmasterol, ursolic acid, oleanolic acid, beta-sitosterol, beta-sitosterol-D-glucoside and p-coumaric acid, have relatively high contents. The preparation method is simple and feasible and is applicable to large-scale production.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine for treating soft-shelled turtle diseases, in particular to a pharmaceutical composition for treating soft-shelled turtle cavitation and a preparation method thereof. Background technique [0002] The pathogens of turtle hole disease include Aeromonas hydrophila, Klebsiella pneumoniae, Alcaligemer spp. and other bacteria. Poor breeding environment and poor feeding lead to bacterial infection, which is the cause of the disease. In the early stage of the disease, some white spots or white spots appear in patches on the carapace, skirt and limbs of the sick turtle, which are strong scabs with a diameter of 0.2 to 1.0 cm. Bleeding around, exposing the cave of the scab, in severe cases, there is bleeding in the cave. The unpicked scabs will soon fall off by themselves, leaving small holes in the original scabs. The edges of the holes are inflamed, and blood flows out of the eyes when ligh...

Claims

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Application Information

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IPC IPC(8): A61K36/8962A61P31/04A61K35/64
Inventor 万传江
Owner XINGHUA HENGWEI BIOTECH
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