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Medical chitosan dressing

A technology of chitosan and raw materials, which is applied in medical science, bandages, absorbent pads, etc., can solve the problems of unsatisfactory hemostasis effect and poor skin fit, and achieve the effect of positive hemostasis effect and simple preparation method.

Inactive Publication Date: 2014-03-26
广州养和生物科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the hemostatic dressings put into clinical use in the industry generally have problems such as unsatisfactory hemostatic effect and poor adhesion to the skin. Therefore, it is still necessary to further improve and improve its hemostatic effect and adhesion to skin tissue.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Put 40 kg of chitosan, 15 kg of hydroxypropyl chitosan, 15 kg of sodium hyaluronate, 5 kg of nano-silver inorganic antibacterial agent, and 8 kg of ciprofloxacin in a stirrer for 10-20 min, and mix Bottle evenly.

Embodiment 2

[0019] Weigh 40 kg of chitosan, 15 kg of hydroxypropyl chitosan, 15 kg of sodium hyaluronate, 5 kg of nano-silver inorganic antibacterial agent, and 8 kg of ciprofloxacin, put them in the reactor, and add 1% ~1.5% acetic acid aqueous solution, stir until fully dissolved; add 10 kg of analytical grade ethylene glycol, continue to stir and heat at a constant temperature of 80~110°C for 15~30 min; pour the mixed solution onto the film-making mold, scrape Flat, after drying fully, remove the film.

Embodiment 3

[0021] Put 30 kg of chitosan, 20 kg of hydroxypropyl chitosan, 12 kg of sodium hyaluronate, 5 kg of nano-zinc oxide, and 8 kg of metronidazole in a blender for 10-20 min, mix well and bottle .

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PUM

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Abstract

The invention discloses a medical chitosan dressing, and a preparation method thereof. The medical chitosan dressing is characterized in comprising following raw materials, by weight, 25 to 40 parts of chitosan, 15 to 25 parts of hydroxypropyl chitosan, 5 to 15 parts of sodium hyaluronate, 1 to 5 parts of an antibacterial agent, 2 to 8 parts of a calming anti-inflammatory agent, and 2 to 10 parts of a plasticizer. The medical chitosan dressing is suitable for medical hemostasis, antibiosis and antiphlogosis, and promoting of wound healing.

Description

technical field [0001] The invention relates to a medical dressing, in particular to a medical chitosan composite dressing and a preparation method thereof. Background technique [0002] Chitin, chitosan and their derivatives have the functions of hemostasis, pain relief, and inhibition of microbial growth, which are all positive for wound healing. At present, the role of chitin, chitosan and their derivatives in promoting wound healing has been proved by many scholars. [0003] The research found that the mechanism of chitosan to promote wound healing is mainly: (1) Accelerate the exudation of PMN cells into the wound area; (2) Accelerate the exudation to form silk fibrin and activate fibroblasts to move to the wound area; ( 3) Stimulate the movement of macrophages; (4) Stimulate the proliferation of fibroblasts and the production of type III collagen fibers. [0004] At present, the hemostatic dressings put into clinical use in the industry generally have problems suc...

Claims

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Application Information

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IPC IPC(8): A61L15/28A61L15/44A61L15/42
Inventor 徐广苓
Owner 广州养和生物科技股份有限公司
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