Externally-used traditional Chinese medicinal compound composition for treating rheumatoid arthritis and preparation method thereof

A composition and compound technology are applied in the field of external-use traditional Chinese medicine compound compositions for treating rheumatoid arthritis and the field of preparation thereof, which can solve the problems of general curative effect of rheumatoid arthritis and the like, and achieve the effects of quick effect, reasonable formula and convenient use.

Active Publication Date: 2014-04-02
JIANGSU KANION PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The curative effect of the existing traditional Chinese medicine for the treatment of rheumatoid arthritis is general, and the present inven

Method used

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  • Externally-used traditional Chinese medicinal compound composition for treating rheumatoid arthritis and preparation method thereof
  • Externally-used traditional Chinese medicinal compound composition for treating rheumatoid arthritis and preparation method thereof
  • Externally-used traditional Chinese medicinal compound composition for treating rheumatoid arthritis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Prescription: Aconitum 25g, Aconitum 25g, Tugucao 25g, frankincense 25g, myrrh 25g, Gentiana chinensis 6g, notopterygium 6g, duhuo 6g, safflower 25g, safflower 6g, angelica 8g.

[0033]Preparation method: Take the prescribed amount of medicinal materials, use 60% ethanol to extract 9 times and 6 times the amount of medicinal materials respectively, and carry out reflux extraction for a total of 2 times, each time for 1 hour, combine the extracted filtrates, concentrate and dry to obtain a Chinese medicine compound composition The extract is added with an appropriate amount of auxiliary materials (stearic acid, lanolin, liquid paraffin, triethanolamine, glycerin, distilled water), and is prepared into an ointment by conventional pharmaceutical methods in traditional Chinese medicine pharmacy.

Embodiment 2

[0035] Prescription: Raw Chuanwu 35g, Shengcaowu 35g, Tugucao 35g, frankincense 35g, myrrh 35g, Gentiana 15g, notopterygium 15g, lovage 15g, safflower 35g, safflower 15g, angelica 20g.

[0036] Preparation method: take the medicinal materials of the prescription amount, carry out reflux extraction with 9 times the amount of medicinal materials with 70% ethanol, each time for 2 hours, combine the extracted filtrates, concentrate and dry to obtain the extract of the Chinese medicine compound composition, add appropriate amount of auxiliary materials (rosin, lanolin , petroleum jelly, liquid paraffin, zinc oxide), rubber is used as the matrix prescription, and the conventional pharmaceutical method in traditional Chinese medicine pharmacy is used to prepare rubber ointment.

Embodiment 3

[0038] Prescription: Raw Chuanwu 30g, Shengcaowu 30g, Tugucao 30g, frankincense 30g, myrrh 30g, Gentiana 10g, notopterygium 10g, lovage 10g, safflower 30g, safflower 10g, angelica 15g.

[0039] Preparation method: Take the prescribed amount of medicinal materials, use 80% ethanol to carry out reflux extraction with 15 times, 10 times, and 5 times of the medicinal materials respectively, for a total of 3 times, each time for 0.5 hours, combine the extracted filtrates, concentrate and dry to obtain The extract of the Chinese medicine compound composition is added with appropriate amount of excipients (dibutyl phthalate, acetone, 70% ethanol), and the conventional pharmaceutical method in Chinese medicine pharmacy is used to prepare a coating agent.

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Abstract

The invention relates to an externally-used traditional Chinese medicinal compound composition for treating rheumatoid arthritis and a preparation method thereof. The externally-used traditional Chinese medicinal compound composition has the functions of dispelling wind and cold, activating blood circulation and stopping pains, is used for treating limb numbness, hand and foot weakness, waist soreness and leg pain, rheumatoid arthritis and hemiplegia sequelae, is reasonable in formulation, convenient and safe to use and quick in effect, and has no obvious toxic and side effects.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine, and relates to an external Chinese medicine compound composition for treating rheumatoid arthritis and a preparation method thereof. Background technique [0002] Rheumatoid arthritis is a chronic systemic autoimmune disease characterized by joint synovitis. Synovitis is persistent and recurrent, which can lead to the destruction of cartilage and bone in the joint, joint dysfunction, and even disability. Vasculitic lesions involving various organs of the body, also known as rheumatoid (RA), is a chronic systemic inflammatory disease of unknown etiology, with chronic, symmetrical, polysynovial arthritis and extra-articular lesions as the main clinical manifestations, An autoimmune inflammatory disease. The disease is prone to occur in small joints such as hands, wrists, and feet, and recurs in a symmetrical distribution. In the early stage, joints are red, swollen, hot, painful, and ...

Claims

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Application Information

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IPC IPC(8): A61K36/714A61P19/02A61P29/00
Inventor 萧伟石学敏王振中丁岗陈俊王丹丹杨时原少伟刘承伟张小龙周军曹亮张红
Owner JIANGSU KANION PHARMA CO LTD
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