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Pharmaceutical composition for treatment of yellow and white diarrhea of piglets

A technology of yellow and white scour of piglets and its composition, which is applied in the direction of active ingredients of heterocyclic compounds, antibacterial drugs, and pharmaceutical formulations, can solve the problems of high incidence and mortality of piglets with yellow and white scour, and prevent dehydration, Supplements the loss of nutrients and inhibits the effect of damage

Inactive Publication Date: 2014-06-04
QINGDAO KDN BIOTECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although the prevention and control methods for piglet yellow and white scour are simple and the cost of prevention and control is low, the incidence and mortality of piglet yellow and white scour in many breeding enterprises are still high, and the losses are very serious

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0007] The preparation method step of chitosan film among the present invention is as follows:

[0008] 1. Dissolve chitosan in 30 mL dilute acetic acid, and centrifuge to remove insoluble matter and air bubbles;

[0009] 2. Put the chitosan solution in a drying oven at 37°C for 24 hours and then take it out;

[0010] 3. Cross-link with sodium tripolyphosphate solution and dry at room temperature to obtain chitosan film.

[0011] The present invention is further illustrated below in conjunction with specific examples.

Embodiment 1

[0013] Accurately weigh 1.2 g of chitosan and dissolve it in 30 mL of dilute acetic acid, centrifuge to remove insoluble matter and air bubbles, place it in a drying oven at 37 °C for 24 h, take it out, and use a concentration of 3% (mass / volume) tripolyphosphoric acid Sodium solution cross-linked and dried at room temperature to obtain chitosan film.

[0014] The chitosan film prepared under this condition is transparent, colorless, homogeneous film, the average thickness of the film is 3.2 μm, amoxicillin can be slowly released for 16 hours, and the drug release rate of 16 hours reaches 82.69%. Glycans are non-toxic, non-irritating, non-teratogenic, and non-sensitizing to cells.

Embodiment 2

[0016] Accurately weigh 0.6g of chitosan and dissolve it in 30 mL of dilute acetic acid, centrifuge to remove insoluble matter and air bubbles, place it in a drying oven at 37 °C for 24 h, take it out, and use a concentration of 1% (mass / volume) tripolyphosphoric acid Sodium solution cross-linked and dried at room temperature to obtain chitosan film.

[0017] The chitosan film prepared under this condition is transparent, colorless, homogeneous film, the average thickness of the film is 2.5 μm, amoxicillin can be released slowly for 8 hours, and the drug release rate of 8 hours reaches 90.31%. Glycans are non-toxic, non-irritating, non-teratogenic, and non-sensitizing to cells.

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PUM

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Abstract

The invention belongs to the technical field of veterinary drugs, the invention discloses a pharmaceutical composition for the treatment of yellow and white diarrhea of piglets, the composition comprises the following raw materials: 50-100 parts of neomycin sulfate, 10-50 parts of scopolamine methobromide, 100-150 parts of montmorillonite, 1-5 parts of VB1, 1-5 parts of VB2, 1-5 parts of VB6, 10-50 parts of niacinamide, 10-50 parts of calcium pantothenate, 1-10 parts of sodium chloride, 1-12 parts of sodium bicarbonate, 1-10 parts of potassium chloride and 100-150 parts of anhydrous dextrose, the pharmaceutical composition is used for treatment of the yellow and white diarrhea of the piglets and dehydration caused by diarrhea, and can effectively control disease rate and mortality of the yellow and white diarrhea of the piglets.

Description

technical field [0001] The invention belongs to the field of animal health products and is used for treating yellow and white scour of piglets and dehydration caused by diarrhea. Background technique [0002] With the development of my country's pig industry, animal disease prevention and control methods are becoming more and more advanced. However, piglet yellow and white scour is still a big stumbling block for breeding enterprises. Although the prevention and control methods of piglet yellow and white scour are simple and the cost of prevention and control is low, the incidence and mortality of piglet yellow and white scour in many breeding enterprises are still high, and the losses are very serious. The pharmaceutical composition provided by the invention comprehensively treats the yellow and white scour of piglets from the aspects of inhibiting pathogens, adsorbing toxins, regulating the balance of water and salt metabolism, etc., and can effectively reduce mortality...

Claims

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Application Information

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IPC IPC(8): A61K33/14A61P31/04A61P31/12A61K31/197A61K31/4415A61K31/455A61K31/46A61K31/51A61K31/525A61K31/7004A61K31/7036A61K33/00A61K33/06
Inventor 崔亮亮郝智慧王艳玲
Owner QINGDAO KDN BIOTECH