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Vitamin C soluble tablet and preparation method thereof

A vitamin and soluble tablet technology, which is applied in the direction of pharmaceutical formula, medical preparations with non-active ingredients, medical preparations containing active ingredients, etc., can solve the problem that vitamin C soluble tablets have not been found yet

Active Publication Date: 2015-04-22
北京朗迪制药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, no relevant reports of vitamin C soluble tablets have been found

Method used

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  • Vitamin C soluble tablet and preparation method thereof
  • Vitamin C soluble tablet and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] A kind of vitamin C soluble tablet, its raw material is:

[0061] Component Amount (g)

[0062] Vitamin C 100

[0063] Lactose 15

[0064] Microcrystalline Cellulose 15

[0065] stearic acid 3

[0066] Polyoxyethylene lauryl ether 12

[0067] 45% ethanol 10

[0068] Preparation:

[0069] 1) Weigh the above ingredients;

[0070] 2) Take vitamin C, spray into 85% ethanol, and granulate;

[0071] 3) Fluidized bed drying, add the remaining ingredients and mix well;

[0072] 4) Sieve through a 30-mesh sieve, measure the weight of the mixture, calculate the weight of the tablet, and press the tablet to obtain the product.

Embodiment 2

[0074] A kind of vitamin C soluble tablet, its raw material is:

[0075] Component Amount (g)

[0076] Vitamin C Calcium Dihydrate 100

[0077] Lactose 20

[0078] Microcrystalline Cellulose 20

[0079] Stearic acid 5

[0080] Polyoxyethylene lauryl ether 15

[0081] 50% ethanol 15

[0082] Preparation:

[0083] 1) Weigh the above ingredients;

[0084] 2) Take vitamin C calcium salt dihydrate, spray into 50% ethanol, and granulate;

[0085] 3) Fluidized bed drying, add the remaining ingredients and mix well;

[0086] 4) Sieve through a 30-mesh sieve, measure the weight of the mixture, calculate the weight of the tablet, and press the tablet to obtain the product.

Embodiment 3

[0088] A kind of vitamin C soluble tablet, its raw material is:

[0089] Component Amount (g)

[0090] Vitamin C Calcium Dihydrate 100

[0091] Lactose 30

[0092] Stearic acid 4

[0093] Polyoxyethylene lauryl ether 16

[0094] 50% ethanol 13

[0095] Preparation:

[0096] 1) Weigh the above ingredients;

[0097] 2) Take vitamin C calcium salt dihydrate, spray into 50% ethanol, and granulate;

[0098] 3) Fluidized bed drying, add the remaining ingredients and mix well;

[0099] 4) Sieve through a 30-mesh sieve, measure the weight of the mixture, calculate the weight of the tablet, and press the tablet to obtain the product.

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PUM

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Abstract

The invention relates to a vitamin C soluble tablet. The medicinal composition is vitamin C or calcium salt dihydrate thereof. The invention also provides a preparation method of the vitamin C soluble tablet. A reasonable auxiliary material formula is selected, so that the vitamin C soluble tablet can be quickly disintegrated within 2 minutes in water and becomes a settled solution form, so that the drug is quickly obtained. By adopting the preparation method disclosed by the invention, vitamin C can be well protected, and oxidation is reduced. Meanwhile, the preparation time is also shortened when the tablet with excellent performance is obtained, and the cost is reduced. The preparation method disclosed by the invention is simple and convenient in process, easy to carry out, and applicable to massive industrial production.

Description

technical field [0001] The invention belongs to the field of pharmaceuticals, and in particular relates to a vitamin C soluble tablet and a preparation method thereof. Background technique [0002] Vitamin C, also known as ascorbic acid, is a water-soluble vitamin with strong reducing properties. Vitamin C is necessary for the formation of collagen, which helps maintain the integrity of interstitial substances such as connective tissue, bone-like tissue, and dentin. The fresh vegetables and fruits that people usually eat contain vitamin C. Therefore, under normal circumstances, as long as they eat a certain amount of fresh vegetables and fruits every day, they will not lack vitamin C. However, once the consumption of vegetables and fruits is limited, due to the human body If you are unable to synthesize vitamin C on your own, you may be ill due to insufficient intake. [0003] According to research, vitamin C has many functions such as treating scurvy, preventing gingival ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K31/375A61K47/12A61K47/32A61K47/34A61K47/26A61K47/38A61P1/02A61P9/10A61P7/06A61P35/00A61P3/02
Inventor 李细海
Owner 北京朗迪制药有限公司
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