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Liquid medicament for lowering body temperature of patient undergoing cardiac surgery under caridiopulmonary bypass

A technique for extracorporeal circulation and cardiac surgery, which is applied in the directions of antipyretics, pharmaceutical formulations, and drug delivery.

Active Publication Date: 2014-06-25
JIANGSU TERRA MEDICAL TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Because ethanol is a volatile liquid, when it evaporates rapidly on the skin, it can absorb and take away a large amount of heat from the body, and has the effect of stimulating the expansion of blood vessels in the skin, so its heat dissipation ability is relatively strong; Excessive secretion of oily secretions, oily secretions hinder the heat dissipation of the skin surface, and the cooling time with ethanol is longer

Method used

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  • Liquid medicament for lowering body temperature of patient undergoing cardiac surgery under caridiopulmonary bypass

Examples

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Embodiment Construction

[0019] The following specific examples illustrate the technical solution of the present invention in detail.

[0020] The cooling medicinal solution for patients undergoing cardiac surgery under general anesthesia and extracorporeal circulation of the present invention is a mixed solution of ethanol, sodium bicarbonate and water, and first prepares the cooling medicinal solution according to the mass ratio of sodium bicarbonate:ethanol:water=5:25:100; Then heat the medicinal solution to 41-45°C; then wet the medicinal solution with a scrubber with rough outer surface and inner layer with strong water absorption; finally, wipe the medicinal solution while massaging the patient's upper limbs, trunk, and lower limbs, and wipe the passage of large blood vessels. For superficial parts (armpit, elbow fossa, groin, rouge, etc.), extend the wiping time to 20 minutes.

[0021] 1. Select objects

[0022] From January 2012 to January 2014, patients undergoing heart surgery or great vess...

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Abstract

The invention discloses a liquid medicament for lowering body temperature of a patient undergoing cardiac surgery under caridiopulmonary bypass. The liquid medicament is characterized by being a mixed solution of ethyl alcohol, sodium bicarbonate and water, wherein the mass ratio of sodium bicarbonate to ethyl alcohol to water is 5:25:100; the temperature of the liquid medicament is 41-45 DEG C. The body temperature lowering effect achieved by means of rubbing bath of ethyl alcohol being 41-45 DEG C is remarkably superior to that of rubbing bath of ethyl alcohol and warm water. By adding an alkaline sodium bicarbonate solution into the mixed solution, oily excreta excreted by sweat gland can be removed effectively, pores are cleaned, and the oily excreta are prevented from blocking the pores and influencing heat dissipation. By adopting the liquid medicament, the temperature lowering time is shortened without influencing the temperature lowering effect or comfort.

Description

technical field [0001] The invention relates to the field of application innovation of a mixed solution of ethanol and sodium bicarbonate, in particular to a cooling medicinal solution for heart surgery patients under general anesthesia and extracorporeal circulation. Background technique [0002] For cardiac surgery patients under general anesthesia and extracorporeal circulation, the body temperature will rise due to the inflammatory reaction; fever higher than 39°C (armpit temperature) will increase the basal metabolic rate, accelerate the circulation, increase the burden on the heart, and accelerate the respiratory rate etc., resulting in dysfunction of various systems of the body. Prolonged high fever can damage brain tissue, so active control of high fever is an important part of the treatment of primary diseases. Drug therapy (application of non-steroidal antipyretic and analgesic drugs) has certain damage to the gastrointestinal tract and kidneys, while physical coo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K33/00A61K9/08A61P29/00
Inventor 吴洪磊许旸晖尤庆生陆凤英薛群史加海
Owner JIANGSU TERRA MEDICAL TECH