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Corneal lamellar piece and production method thereof

A lamellar and corneal technology, used in biology, ophthalmic medicine, and medical fields, can solve the problems of prolapse of eyeball contents, disappearance of cavities, and inability to repair in time, so as to reduce the cost of surgery and solve the problem of excessive waiting time. Effect

Inactive Publication Date: 2014-07-02
薛春燕
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Due to the lack of corneal repair materials, many patients with corneal ulcer perforation cannot be repaired in time for a long time, resulting in the disappearance of the cavity between the iris and cornea of ​​the eyeball, resulting in prolapse of the eyeball content, eyeball collapse, and irreversible eyeball damage.

Method used

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  • Corneal lamellar piece and production method thereof
  • Corneal lamellar piece and production method thereof
  • Corneal lamellar piece and production method thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0037] First of all, the patients who underwent full femtosecond laser corneal refractive surgery signed a surgical agreement, and voluntarily donated corneal stroma lenses for clinical treatment. And carry out blood infectious disease inspection, mainly including HIV, HBV, HCV and syphilis and other inspection items. Then, according to the family medical history and social history provided by the patient, unsuitable groups such as drug addicts are excluded.

[0038] Mark the surgical patients who meet the requirements, and collect the corneal stroma lens discarded as medical waste in the full femtosecond laser corneal refractive surgery, mark the corneal stroma lens, and obtain the diameter of the marked corneal stroma lens according to the operation parameter record and the central thickness, the corneal stromal lens that is collected is called the corneal stromal lens unit;

[0039] Record the diameter and central thickness of each corneal stroma lens unit respectively, an...

Embodiment 2

[0054] The repaired patient was a patient with a peripheral corneal perforation. It can be seen that the anterior chamber has disappeared due to the perforation of the cornea in his eye. Its eye perforation is 4.0mm, such as image 3 as shown in a.

[0055] First, the patient's corneal wound was marked with a 4.0mm corneal trephine, and then the necrotic material in the marked ring was removed. Afterwards, the corneal stromal lamina was removed from the glycerin, and the corneal stromal lamella was circumcised with a 4.0mm trephine to form a 4.0mm repair material, which was then sutured to the corneal wound with 10-0 nylon suture.

[0056] After the repair is healed, wait for the visual acuity to improve on its own. After the repair, the OCT image of the eye is as follows: image 3 as shown in b.

[0057]

Embodiment 3

[0059] The repaired patient is a patient with a perforation in the center of the eyeball, and the photo of the eye before repair is as follows Figure 4 as shown in a.

[0060] First, the patient's corneal wound was marked with a 5.5mm corneal trephine, and then the necrotic material in the marked ring was removed. Afterwards, the corneal stromal lamella was removed from the glycerin, and the corneal stromal lamella was cut with a 5.5mm trephine to form a 5.5mm repair material, which was then sutured to the corneal wound with a 10-0 nylon thread to repair the posterior eye photos such as Figure 4 as shown in b.

[0061] After the inflammation disappears, elective optical corneal transplantation can be performed to improve vision.

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Abstract

The invention relates to the fields of biology and medicine, particularly relates to the field of ophthalmic medicine, in particular to a corneal lamellar piece and a production method thereof, and aims to solve the problem existing in current treatment repairing. The corneal lamellar piece is formed by stacking stromal corneal lens units, fibrin adhesive layers are arranged among the stromal corneal lens units, the maximum thickness of the corneal lamellar piece ranges from 350 to 450micrometer, and the diameter of the corneal lamellar piece ranges from 6 to 6.5mm. The stromal corneal lens units are made from operation garbages of femtosecond laser corneal refractive operations, so that the operation garbages are converted into repairing materials urgently needed in eyeball treatment repairing, the problem that material waiting period in eyeball treatment repairing is long is solved, operation cost is reduced greatly, and the corneal lamellar piece is significant in the ophthalmic medical field.

Description

[0001] technical field [0002] The invention relates to the fields of biology and medicine, in particular to the field of ophthalmology, and more specifically relates to a corneal lamellar sheet and a preparation method thereof. [0003] Background technique [0004] Eyeball repair is divided into optical repair and therapeutic repair. The so-called optical repair refers to the need to restore the vision of the eyeball, which requires that the repair material must be the cornea provided by the donor, and the transparency of the cornea must be ensured so that the recipient can restore vision. However, therapeutic repair is only to ensure the integrity of the eyeball, repair eyeball perforation, and prevent the loss of ocular contents and the spread of infection in the eye. transplant. [0005] However, due to the influence of conventional thinking or preconceived thinking in this field, those skilled in the art have not clearly separated these two materials with different...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61F2/14
Inventor 薛春燕
Owner 薛春燕
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