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Traditional Chinese medicine composition for treating osteoporosis and preparation method thereof

An osteoporosis and composition technology, which is applied in the field of traditional Chinese medicine compositions for the treatment of osteoporosis and the preparation thereof, can solve the problems of lack of random control observation, adverse effects on physiological functions, low appetite and the like, and achieves safe, reliable and safe clinical medication. Induces appetite loss and increases bone density

Active Publication Date: 2014-07-16
泸州市中医医院
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, a large number of prescriptions are basically based on the means of tonifying the kidney and consolidating essence, promoting qi and activating blood circulation. The long-term use of medicinal materials in the prescription can damage the stomach qi and make the spleen and stomach lose their nourishment. Over time, it will cause people's appetite to be depressed, which is even more unfavorable for nutritional intake. adverse effects on overall physiology
At the same time, most of the current clinical trials of traditional Chinese medicine still lack random, blind, controlled observation, the sample size is generally small, and there is also a lack of long-term observation and follow-up reports

Method used

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  • Traditional Chinese medicine composition for treating osteoporosis and preparation method thereof
  • Traditional Chinese medicine composition for treating osteoporosis and preparation method thereof
  • Traditional Chinese medicine composition for treating osteoporosis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] [Ingredients] Angelica 100g, Chuanxiong wine 50g, Rehmannia glutinosa 200g, Wujiapi 70g, Guiji 50g, Eucommia salt 50g, Dipsacus 50g, Baiji 50g, Drynaria 70g Keel 50g, Panax notoginseng 50g, Astragalus 150g, Codonopsis 150g, natural copper forging 50g, papaya 50g, epimedium 90g, fennel 100g, ground beetle 70g, dodder salt 100g gram, psoralen salt 100 grams.

[0026] [Preparation method] In the composition of the above weight parts, except rehmannia glutinosa, eucommia salt system, baiji, drynaria fortunei, astragalus, codonopsis root, papaya, dodder, epimedium, and fennel, other ten flavors such as angelica are crushed into fine powder, passed through a 80-mesh sieve, and mixed well; Reflux extraction for 1 hour, filter the extract, concentrate the filtrate into an extract with a relative density of 1.15, dry it, mix it with fine powder, add 120 grams of honey to make a pill, and dry it to get it.

Embodiment 2

[0028] [Ingredients] Angelica 130g, Chuanxiong wine 70g, Rehmannia glutinosa 250g, Wujiapi 90g, Guiji 70g, Eucommia salt 70g, Dipsacus 70g, Baiji 70g, Drynaria 90g Keel 70g, Panax notoginseng 70g, Astragalus 180g, Codonopsis 180g, natural copper forging 70g, papaya 70g, epimedium 120g, fennel 130g, ground beetle 90g, dodder salt 130g gram, psoralen salt 130 grams.

[0029] [Preparation method] In the composition of the above weight parts, except rehmannia glutinosa, eucommia salt system, baiji, drynaria fortunei, astragalus, codonopsis root, papaya, dodder, epimedium, and fennel, other ten flavors such as angelica are crushed into fine powder, passed through a 100-mesh sieve, and mixed well; Reflux extraction for 2 hours, filter the extract, concentrate the filtrate into an extract with a relative density of 1.20, dry it, mix it with fine powder, add 160 grams of honey to make a pill, and dry it to get it.

Embodiment 3

[0031] [Ingredients] Angelica 120g, Chuanxiong wine 60g, Rehmannia glutinosa 240g, Wujiapi 80g, Guiji 60g, Eucommia salt 60g, Dipsacus 60g, Baiji 60g, Drynaria 80g 60 grams of keel, 60 grams of Panax notoginseng, 160 grams of astragalus, 160 grams of Codonopsis pilosula, 60 grams of natural copper forging, 60 grams of papaya, 100 grams of epimedium, 120 grams of fennel, 80 grams of ground beetle, 120 grams of dodder salt gram, psoralen salt 120 grams.

[0032] [Preparation method] In the composition of the above weight parts, except rehmannia glutinosa, eucommia salt system, baiji, drynaria fortunei, astragalus, codonopsis root, papaya, dodder, epimedium, and fennel, other ten flavors such as angelica are crushed into fine powder, pass through a 90-mesh sieve, and mix well; Reflux extraction for 1.5 hours, filter the extract, concentrate the filtrate into an extract with a relative density of 1.17, dry it, mix it with fine powder, add 150 grams of honey to make a pill, and dr...

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Abstract

The invention discloses a traditional Chinese medicine composition for treating osteoporosis. The traditional Chinese medicine composition is prepared from the following raw materials: angelica sinensis, wine-processed rhizoma chuanxiong, prepared rehmannia root, cortex acanthopanacis, cassia twig, salt-processed bark of eucommia, radix dipsaci, rhizoma bletillae, sand-scorch-processed drynaria rhizome, fossil fragments, pseudo-ginseng, radix astragali, dangshen, calcined native copper, pawpaw, herba epimedii, rhizoma dioscoreae hypoglaucae, ground beeltle, salt-processed semen cuscutae and salt-processed fructus psoraleae. The traditional Chinese medicine composition provided by the invention is capable of remarkably increasing the bone mineral density and relieving bone pain. The traditional Chinese medicine composition prepared from combination of the multiple components has a remarkable and definite curative effect on osteoporosis treatment and no obvious acute toxicity reaction, does not cause anorexia during treatment and is safe and reliable in a clinical medication process.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating osteoporosis and a preparation method thereof. Background technique [0002] Osteoporosis (OP) is a kind of metabolic bone disease, which is a systemic bone disease characterized by decrease in bone mass and degeneration of microstructure, resulting in increased bone fragility and susceptibility to fracture; It is divided into two categories: primary osteoporosis and secondary osteoporosis, of which primary osteoporosis accounts for about 90%. Epidemiological surveys show that the incidence of osteoporosis is highest in Asia and Latin America. According to a large-scale national epidemiological survey in 2006, about 69.44 million people over the age of 50 suffer from osteoporosis, and more than 200 million people suffer from low bone mass. The incidence rate of women is significantly higher than that of men. With the prolongation of human life expectancy, population agin...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P19/10A61K35/02A61K33/26A61K35/64A61K9/20
Inventor 唐中尧张世波未秋平郑磊连杰陈晓梅杨陈一刘永森
Owner 泸州市中医医院
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