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Medicinal composition with bleeding-stopping, pain-relieving and inflammation-diminishing effects, preparation method and application thereof

An anti-inflammatory effect, hemostasis and pain-relieving technology, applied in the direction of drug combination, medical preparations containing active ingredients, anti-inflammatory agents, etc., can solve the problems of unsatisfactory treatment effect, achieve significant hemostasis, pain-relieving and anti-inflammatory effects, good treatment effect of effect

Active Publication Date: 2014-07-16
FUJIAN ZHONGHE MEDICINE CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Therefore, when the clinical situation is accompanied by bleeding, pain and inflammatory symptoms, the therapeutic effect of these drugs is not ideal

Method used

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  • Medicinal composition with bleeding-stopping, pain-relieving and inflammation-diminishing effects, preparation method and application thereof
  • Medicinal composition with bleeding-stopping, pain-relieving and inflammation-diminishing effects, preparation method and application thereof
  • Medicinal composition with bleeding-stopping, pain-relieving and inflammation-diminishing effects, preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1-7

[0049] Embodiments 1-7 are respectively pharmaceutical compositions made from raw materials in proportions by weight shown in Table 1 below:

[0050] The raw material medicine weight proportion of table 1 embodiment 1-7

[0051]

Embodiment 1-3

[0052] The preparation method of embodiment 1-3:

[0053] According to the raw material proportioning of above-mentioned embodiment 1-3, make oral capsule, external use spray, external use liniment respectively by the method comprising following main steps:

[0054] (1) Phellodendron Phellodendri, Forsythia japonicus, Sophora flavescens, Duyiwei, Baiji, and Safflower in the crude drug are combined together, and the volume percentage is 70% ethanol aqueous solution, and the addition is according to the weight of the crude drug: liquid volume=1g: 10ml is calculated, extracted by heating, filtered, and the filtrate is concentrated to obtain extract A1;

[0055] (2) Mix red stone fat, Galla gall, dried blood, and menthol in the raw material medicine, and grind them into fine powder to obtain fine powder mixture B1;

[0056] (3) Mix the extract A1 of the above step (1) and the fine powder mixture B1 of the step (2) to obtain a pharmaceutical composition C;

[0057] (4) Take the p...

Embodiment 4-7

[0058] The preparation method of embodiment 4-7:

[0059] According to the raw material proportioning of above-mentioned embodiment 4-7, by comprising the method for following main steps, make external ointment:

[0060] (1) Combine Cortex Phellodendron, Forsythia, Sophora Sophora, Duyiwei, Baiji and Safflower in the crude drug, add water 8 times the weight of the crude drug, decoct and extract 3 times, After filtering, combining the filtrates and concentrating to obtain extract A1;

[0061] (2) Beat red stone fat, Galla gall, dried blood, and menthol in the crude drug into fine powders respectively, and then mix them uniformly to obtain fine powder mixture B1;

[0062] (3) Mix the extract A1 of the above step (1) and the fine powder mixture B1 of the step (2) to obtain a pharmaceutical composition C;

[0063] (4), take the pharmaceutical composition C of the above step (3), and make an external ointment according to the conventional preparation method of ointment.

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Abstract

The invention discloses a medicinal composition with bleeding-stopping, pain-relieving and inflammation-diminishing effects, a preparation method and an application thereof. The medicinal composition is prepared from the following raw medicinal materials: cortex phellodendri, fructus forsythiae, sophora flavescens, lamiophlomis rotata, rhizoma bletillae, safflower, red halloysite, gallnut, dragon blood and menthol. The medicinal composition can generate a remarkable synergetic effect due to the compatibility of the raw medicinal materials, has remarkable bleeding stopping, pain relieving and inflammation diminishing effects due to experiment verification, and has good effects in the aspects of treating various bleeding, paining and inflammation symptoms, haemorrhoids and the like.

Description

technical field [0001] The invention belongs to the technical field of pharmacy, and in particular relates to a pharmaceutical composition with hemostatic, pain-relieving and anti-inflammation effects, its preparation method and application. Background technique [0002] Traumatic injuries, gastrointestinal bleeding, hemorrhoids and other diseases are usually accompanied by bleeding and pain symptoms, and sometimes inflammatory symptoms at the same time. Therefore, in clinical practice, anti-inflammatory treatment is usually considered at the same time as hemostasis and pain relief. However, Currently, there are not many drugs that have both hemostatic, pain-relieving and anti-inflammatory effects available clinically. For example, Yunnan Baiyao, a drug commonly used clinically to stop bleeding and relieve pain, has the functions of removing blood stasis and stopping bleeding, promoting blood circulation and relieving pain, but its anti-inflammatory effect is not obvious. A...

Claims

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Application Information

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IPC IPC(8): A61K36/898A61P7/04A61P29/00A61P9/14A61K33/26A61K31/045
Inventor 陈铭魁
Owner FUJIAN ZHONGHE MEDICINE CO LTD
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