Unlock instant, AI-driven research and patent intelligence for your innovation.

A method for preparing bisphenol A molecularly imprinted polymers by combining semicovalent method and raft

A molecular imprinting and semi-covalent technology, applied in chemical instruments and methods, other chemical processes, etc., can solve the problem of unclear hole contours of bisphenol A molecularly imprinted polymers, too deep embedding of imprinted sites, and intermolecular Insufficient bonding, etc., to improve the recognition efficiency and adsorption rate, the bonding between molecules is firm, and the polymer film is evenly distributed.

Inactive Publication Date: 2016-06-01
HEILONGJIANG UNIV
View PDF3 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The purpose of the present invention is to solve the problems of unclear hole profile, slow re-adsorption speed, wide molecular weight distribution, weak intermolecular bonding, poor specific adsorption capacity, and embedding of imprinted sites in the bisphenol A molecularly imprinted polymer prepared by the existing method. Problems such as too deep and bisphenol A leakage, provide a method for preparing bisphenol A molecularly imprinted polymers by combining semi-covalent method and RAFT

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • A method for preparing bisphenol A molecularly imprinted polymers by combining semicovalent method and raft
  • A method for preparing bisphenol A molecularly imprinted polymers by combining semicovalent method and raft
  • A method for preparing bisphenol A molecularly imprinted polymers by combining semicovalent method and raft

Examples

Experimental program
Comparison scheme
Effect test

specific Embodiment approach 1

[0021] Specific embodiment 1: In this embodiment, the method of preparing bisphenol A molecularly imprinted polymer by combining semi-covalent method and RAFT is completed according to the following steps:

[0022] 1. Silica gel activation: ultrasonically disperse the silica gel in a hydrochloric acid solution with a mass fraction of 8% to 15%, stir and reflux for 10 to 30 hours at a temperature of 20 to 30°C, and wash the obtained solid product with pure water until it is filtered Until the liquid is neutral, the washed solid product is put into a muffle furnace and roasted at 350-450°C for 15-25 hours to obtain activated silica gel;

[0023] 2. Surface modification of silica gel: ultrasonically disperse activated silica gel in toluene, then add tetrachloromethylphenyltrichlorosilane and triethylamine under nitrogen protection, stir at 40-60°C for 20-30h, centrifuge The separated solid phase is ultrasonically cleaned with toluene for 5 to 6 times, and then centrifuged to obta...

specific Embodiment approach 2

[0029]Specific embodiment 2: The difference between this embodiment and specific embodiment 1 is that the silica gel described in step 1 is 50-100nm amorphous silica gel, 100-200nm amorphous silica gel, 200-300nm amorphous silica gel, 50-100nm spherical silica gel , 100-200nm spherical silica gel or 200-300nm spherical silica gel. Others are the same as in the first embodiment.

[0030] The silica gels of different specifications described in this embodiment can be obtained commercially.

specific Embodiment approach 3

[0031] Specific embodiment three: the difference between this embodiment and specific embodiment one or two is that the mass ratio of the silica gel described in step one to the hydrochloric acid solution with a mass fraction of 8% to 15% is 1g: (5mL to 15mL) . Other steps and parameters are the same as those in Embodiment 1 or Embodiment 2.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
thicknessaaaaaaaaaa
adsorption capacityaaaaaaaaaa
adsorption capacityaaaaaaaaaa
Login to View More

Abstract

The invention relates to a method for preparing a bisphenol A molecularly imprinted polymer, in particular to a method for preparing the bisphenol A molecularly imprinted polymer by the utilization of a combination of a semi-covalent method and RAFT. The problems that in an existing bisphenol A molecularly imprinted polymer, binding between molecules is not firm, the capacity for specific absorption is poor, and bisphenol A leakage happens are solved. The method for preparing the bisphenol A molecularly imprinted polymer includes the steps that firstly, silica gel is dispersed in hydrochloric acid to obtain activated silica gel; secondly, surface modification is performed on the silica gel to obtain 4-(Chloromethyl) phenyltrichlorosilane grafted silica gel; thirdly, the silica gel is subjected to a chain transfer reagent to obtain a silica ball to which the RAFT chain transfer reagent is grafted; fourthly, polymerization reaction is performed to obtain the polymer through preparation; fifthly, hydrolysis elution is performed to prepare the molecularly imprinted polymer. The prepared bisphenol A molecularly imprinted polymer film is thin, the binding between the molecules is firm, the resolution ratio and the absorption rate are increased, the removal rate of bisphenol A can reach over 75%, and meanwhile the problem of template molecule leakage in the absorption process is solved.

Description

technical field [0001] The invention relates to a preparation method of bisphenol A molecularly imprinted polymer. Background technique [0002] Bisphenol A is one of the most widely used industrial raw materials in the world, and it is also a typical environmental endocrine disruptor. The concentration of bisphenol A in the actual sample is low (the content is generally in ng·L -1 or μg·L -1 level) and the environmental matrix is ​​complex, so it is necessary to prepare a polymer with specific selectivity for the specific target molecule bisphenol A to pretreat and enrich the sample. [0003] The preparation methods of bisphenol A molecularly imprinted polymer mainly include covalent method, non-covalent method and semi-covalent method. Among them, the adsorption process of molecularly imprinted polymers prepared by the covalent method takes a long time and the reaction conditions are harsh. The molecularly imprinted polymers prepared by the non-covalent method have uncl...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): C08F292/00C08F222/14C08F2/38C08J9/26B01J20/26B01J20/30
Inventor 王滨松刘扬李锋苑晨
Owner HEILONGJIANG UNIV