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Mouth rinse composition

A technology of composition and mouthwash, applied in oral care, medical science, dentistry, etc., can solve problems such as increased cost, inability to effectively eliminate odor, damaged gums or crowns, etc., to achieve odor elimination, low sensitivity, The effect of preventing bacterial infection

Inactive Publication Date: 2014-09-10
FAR EASTERN NEW CENTURY COPRRATION
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] U.S. Patent No. 5,753,217 provides a method for reducing bad breath, using a mixed solution of chlorous acid and zinc salt as a mouthwash, but this method can only suppress bad breath and cannot effectively eliminate odors
In addition, Taiwan Patent No. I305497 provides a multi-ingredient tooth powder, although it can effectively eliminate bad breath, thickeners, wetting agents, etc. must be added as needed for ease of use, which not only increases the cost of preparation, but also the tooth powder After mixing, it will produce irritating chlorine dioxide, causing damage to gums or crowns

Method used

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  • Mouth rinse composition
  • Mouth rinse composition
  • Mouth rinse composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Take 10.0 grams of polyglutamic acid (Polyglutamic acid, molecular weight about 2,000,000, Vedan, Taiwan) into a 250ml single-necked bottle, add 90ml of pure water to dissolve it, and prepare a polyglutamic acid aqueous solution. Add 4 g of 12.65 wt% sodium hypochlorite aqueous solution to form a mixed solution. The mixture was stirred continuously at room temperature for 30 minutes to react polyglutamic acid with sodium hypochlorite. The reacted mixed solution was placed in a separatory funnel, polymer 1 was precipitated with isopropanol, and after polymer 1 was separated from the separatory funnel, it was placed in a vacuum oven for drying. The dried product is a white to pale yellow powder, which can be completely dissolved in water. The dried polymer 1 was titrated with sodium thiosulfate to finally obtain the weight percentage of the N-Cl haloamine functional group in the modified polyglutamic acid.

Embodiment 2~6

[0048] The embodiment is as described in Example 1, but the sodium hypochlorite aqueous solution is added into the polyglutamic acid aqueous solution with the weight of 12, 20, 28, 36 and 40 g, respectively. The mixture was stirred continuously at room temperature for 30 minutes to react polyglutamic acid with sodium hypochlorite. Put the reacted mixed solution in a separatory funnel respectively, precipitate polymers 2-6 with isopropanol, separate polymers 2-6 from the separatory funnel, and place them in a vacuum oven for drying. The dried product is a white to pale yellow powder, which can be completely dissolved in water. The dried polymers 2-6 were respectively titrated with sodium thiosulfate, and finally the weight percentage of the N-Cl haloamine functional group in the modified polyglutamic acid was obtained.

Embodiment 7~8

[0050] Embodiment and proportioning are as described in Example 1, but the time of stirring the mixed solution at room temperature is extended to 90 and 180 minutes respectively, after the reaction time is reached, the mixed solution after the reaction is similarly placed in a separatory funnel, Polymers 7 and 8 were precipitated with isopropanol, and polymers 7 and 8 were separated out of a separatory funnel and placed in a vacuum oven for drying. The dried product is a white to pale yellow powder, which can be completely dissolved in water. The dried polymers 7 and 8 were respectively titrated with sodium thiosulfate to finally obtain the weight percentage of the N-Cl haloamine functional group in the modified polyglutamic acid.

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Abstract

The invention discloses a mouth rinse composition. The mouth rinse composition comprises water and modified polyglutamic acid. The modified polyglutamic acid comprises multiple chain segments A and multiple chain segments B, and the multiple chain segments A and multiple chain segments B are arranged randomly. The chain segment A has a chemical formula I and the chain segment B has a chemical formula II, wherein in the formulas, X represents H, Na, K, NH4, 1 / 2Ca or 1 / 2Mg and Y represents Cl, Br or I. A concentration of the modified polyglutamic acid in the mouth rinse composition is in a range of 0.1-5wt%. The mouth rinse composition can remove halitosis, has antibacterial properties, and can prevent dental plaque thereby preventing periodontosis.

Description

technical field [0001] The invention relates to a mouthwash composition, in particular to a mouthwash composition capable of eliminating bad breath and preventing periodontal disease. Background technique [0002] Ordinary people are most afraid of encountering bad breath when they meet face to face. Severe bad breath will affect interpersonal relationships and social activities. [0003] Bad breath is mainly caused by the unpleasant smell emitted by volatile compounds in the oral cavity, such as volatile sulfides, short-chain fatty acids, polyamines, alcohols, phenols, alkanes, ketones and nitrogen compounds Among them, volatile sulfides are the main cause of bad breath. Scholars have proposed in the past (Tonzetich J, Richter VJ. Evaluation of volatile odoriferous components of saliva. Arch Oral Biol, 9:39-45, 1964), adding different substances to whole saliva to explore ammonia Which one of sulfide and sulfide is the most likely to produce an odor in the mouth? It was f...

Claims

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Application Information

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IPC IPC(8): A61K8/84A61Q11/00
Inventor 吴勇毅李俊谊李致达
Owner FAR EASTERN NEW CENTURY COPRRATION
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