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Plant essential oil composition for veterinary use

A plant essential oil and composition technology, applied in the directions of drug combinations, plant raw materials, active ingredients of hydroxyl compounds, etc., can solve the problems of increased transportation, storage and other costs, limited solubility, product turbidity, etc., and achieves low cost and reduces antibiotics. Use, pharmacological action clear effect

Active Publication Date: 2014-10-01
烟台爱士津动物保健品有限公司
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  • Abstract
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  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In addition, due to the high use concentration, it is necessary to require a high concentration of the drug in the product (most of the existing similar products have a concentration of 20% to 40%, and the product itself uses more water solvent), and water is used as a solvent for the emulsion. The solubility of the product is limited, and when the drug concentration is high, it cannot be completely dissolved and the product is turbid or layered. Therefore, conventional products increase the amount of solvent (water) to increase the content of natural plant extracts, so that the product does not have a high drug content. In the case of high volume, the volume is large, which increases the cost of transportation and storage during the use of natural plant extracts

Method used

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  • Plant essential oil composition for veterinary use
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  • Plant essential oil composition for veterinary use

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 5

[0025] Example 5 Preparation of a Veterinary Plant Essential Oil Composition

[0026] Prescription: as the prescription among the embodiment 1~4.

[0027] preparation:

[0028] (1) Take the prescribed amount of ethanol, isopropanol, propylene glycol and polyethylene glycol 400, mix them, stir evenly, and use it as a solvent for later use.

[0029] (2) Weigh the prescribed amount of Tween-80, RH-40 and MSE, and stir well.

[0030] (3) Add the prescribed amount of mugwort oil, eucalyptus oil, vitex oil, menthol and Ledum oil to (2) in sequence, and stir well.

[0031] (4) Slowly add the solution of (1) into (3), and stir while adding. Instantly.

Embodiment 6

[0032] Example 6 Prescription Screening and Oil Phase Stability

[0033] In the present invention, through prescription screening and test excavation, it is found that eucalyptus oil and menthol have outstanding effects on the stabilization and solubilization of the oil phase. Experimental comparison and screening found that when the proportions of eucalyptus oil and menthol in the oil phase were 20% to 30% and 10% to 20% respectively, and when the ratio of eucalyptus oil: menthol was 1.5:1, mugwort oil, eucalyptus oil, The oil phase composed of Vitex oil, Menthol and Ledum oil has the best stability in the product.

[0034] Table 2 Oil phase stability screening test

[0035]

[0036] Prepare samples according to four groups of prescriptions of A, B, C and D in Table 2 respectively, leave it at room temperature for 48 hours, observe and record the situation of the four groups of samples at 6 hours, 12 hours, 24 hours and 48 hours respectively (the results are as follows: ...

Embodiment 7

[0041] The selection of embodiment 7 surfactant

[0042] Experimental method: Take mugwort leaf oil, eucalyptus oil, Vitex oil, menthol and Ledum oil in the prescription amount in Example 1 and place them in a beaker, add different amounts of Tween-80, RH-40 or MSE respectively, and set the temperature with propylene glycol. content, mix well. Take 1ml and mix it with water at different ratios of 1:10, 1:50, 1:100, 1:200, 1:300, 1:500, and 1:1000, stir while adding, and observe the clarity of the solution. In addition, the solubility of MENTOFIN, a similar product from Germany, was also investigated, and the results are shown in Table 4, Table 5, Table 6, Table 7, Table 8, and Table 9.

[0043] Table 4 Experimental results of Tween-80 solubilizing volatile oil

[0044]

[0045] Table 5 RH-40 solubilized volatile oil experimental results

[0046]

[0047] Table 6 Experimental results of MSE solubilized volatile oil

[0048]

[0049] Table 7 Experimental results o...

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Abstract

Plant essential oil composition for veterinary use is disclosed. The plant essential oil composition comprises 12-60% by weight of an oil phase, 5-50% by weight of a surfactant, and 0-80% by weight of a solvent. The oil phase relates to a mixture of two or several compounds selected from blumea oil, eucalyptus oil, vitex oil, menthol and ledum oil. The surfactant is tween-80, RH-40 and MSE (polyoxyethylene methyl glucoside sesquistearate). The solvent is propylene glycol, polyethylene glycol 400, isoamyl alcohol and ethanol. The composition has functions of relieving cough and eliminating phlegm, an anti-inflammatory function, an antibacterial function, and the like, and can be used for treating respiratory diseases of livestock and poultry. The composition has characteristics of high stability, high dispersibility, high bioavailability, capability of taking effects rapidly, and the like.

Description

technical field [0001] The invention belongs to the technical field of veterinary medicine, and in particular relates to a veterinary plant essential oil composition, which has high essential oil content, is soluble in water, and can be conveniently applied to the prevention and auxiliary treatment of livestock and poultry respiratory diseases. Background technique [0002] Natural plant extracts have attracted extensive attention from scientific researchers and livestock farmers due to their significant curative effect, environmental protection, and no residue. However, there are still many problems and defects in the use of natural plant extracts. [0003] Natural plant extracts themselves are insoluble in water, and in the actual production of modern and large-scale farms, livestock and poultry medicines are generally used mixed with water, especially in large-scale chicken farms, the most convenient form of administration is group drinking water administration. Single-d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/85A61K47/34A61K47/10A61K9/08A61P11/00A61P11/10A61P11/04A61K31/045
Inventor 刘哲林吕淑荣冷鲁南姜莹
Owner 烟台爱士津动物保健品有限公司
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