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Tomato extract as well as preparation method and application thereof

A tomato extract, tomato technology, applied in the direction of pharmaceutical formula, cosmetic preparations, dressing preparations, etc., to achieve the effect of convenient operation, safe and reliable performance, and simple preparation process

Inactive Publication Date: 2014-11-19
SHANGHAI INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, chemically synthesized whitening agents have relatively large side effects. In recent years, people have turned to natural whitening agents. Some plant active substances such as arbutin, vitamin C, derivatives of kojic acid, and green tea extracts have whitening effects.

Method used

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  • Tomato extract as well as preparation method and application thereof
  • Tomato extract as well as preparation method and application thereof

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Experimental program
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Effect test

Embodiment 1

[0020] A tomato extract, specifically prepared by a method comprising the following steps:

[0021] (1) Wash the tomatoes, crush and homogenate to obtain a tomato homogenate;

[0022] 100g of tomato homogenate and 400ml of water are calculated according to the mass ratio, that is, tomato homogenate: water is mixed in a ratio of 1:4 to obtain a mixed solution;

[0023] (2), the mixed solution obtained in step (1) is extracted with ultrasonic assistance, the power of ultrasonic-assisted extraction is 80w, and the time is 10min;

[0024] After ultrasonic-assisted extraction, extract in a water bath at 45°C for 35 minutes, centrifuge in a refrigerated centrifuge at 8000r / min, 4°C for 15 minutes after extraction, filter the obtained supernatant, and collect the obtained filtrate, which is the tomato extract;

[0025] (3) The tomato extract filtrate obtained in step (2) is controlled by a rotary evaporator at a pressure of 0.08-0.1 MPa, and the temperature is 50-65°C for reduced pr...

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Abstract

The invention discloses a tomato extract as well as a preparation method and application thereof. The preparation method comprises the following steps: firstly, cleaning a tomato, crushing and homogenizing to obtain a tomato homogenate liquid; mixing the tomato homogenate liquid and water to obtain a mixed liquid; extracting the mixed liquid by ultrasonic assistance with power of 30-40w for 6-10 minutes; extracting in a water-bath kettle at 45 DEG C for 30-40 minutes after the ultrasonic-assisted extraction; centrifuging on a refrigerated centrifuge at 8000r / min and 4 DEG C for 15 minutes after the extraction is completed so as to obtain supernate; filtering the supernate, controlling the pressure of the filtrate to be 0.08-0.1MPa, and concentrating at reduced pressure and 50-65 DEG C; and controlling the temperature of the concentrated residue to be minus 20-minus 40 DEG C, and freezing and drying to obtain the tomato extract. The extract is capable of inhibiting tyrosinase, can be applied to whitening skin-care products as a tyrosinase inhibitor, is safe and reliable in performance, and does not have side effect. The preparation method is simple, and is convenient to operate.

Description

Technical field [0001] The present invention is a plant -active extraction field, which involves a tomato extract and its preparation methods and the application as a tyrosinase inhibitor. Background technique [0002] Generally, the color of human skin mainly depends on the content and distribution of melanin, and the structural function and quantity of melanocytes directly affect the melanin content in the skin. It is the decisive factor that produces melanin.On the skin, melanocytes are located at the base layer of the dermis and epidermis.Melanocytes are glandular cells and have tree protrusions. It forms an epidermal melanin unit with keratinocytes.The melanin is formed by a series of oxidation reactions. Tyinase can catalyze the three different reactions in melanin biomestin in melanocytes: Tyrine (TYR) is catalyzed to multiple transformers in Typeine enzymes (TYR)DOPA, DOPA transformed into Daba (DQ) under the action of tyrosinase, and the automatic oxidation of Doba is tr...

Claims

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Application Information

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IPC IPC(8): A61K8/97A61Q19/02A61Q19/08
Inventor 龚钢明韩佳王沁张婉萍
Owner SHANGHAI INST OF TECH
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