Compound Chinese herb extract immunoenhancer for megalobrama amblycephala as well as preparation method and application thereof

Abstract

The invention relates to a compound Chinese herb extract immunoenhancer for megalobrama amblycephala as well as a preparation method and application thereof, belonging to the technical field of aquatic formula feed. The immunoenhancer comprises gallnut, rheum officinale, fructus forsythiae, liquorice, radix astragali, oldenlandia diffusa, burdock, etc.; the various components are sliced, and are refluxed, concentrated and extracted in a water bath, and then filtrate is concentrated in a vacuum environment and is spray-dried to prepare dry powder of the compound Chinese herb extract immunoenhancer. The immunoenhancer disclosed by the invention is stable in raw material resource, simple to prepare, broad in material source and low in cost, and has characteristics of being natural, free from residue, low in toxic and side effect, etc.; viewed from theory of traditional Chinese medicine, the compound Chinese herb extract immunoenhancer can make compensation for direct formulation of Chinese herbal medicines or application of single Chinese herb extract in aquaculture, and is low in amount of additive; the immunoenhancer, when being used, can enhance immunity and oxidation resistance of fish, resist infection ability of aeromonas hydrophila and promote growth of megalobrama amblycephala.

Description

technical field [0001] The invention relates to a compound Chinese herbal medicine extract immunopotentiator for bream and its preparation method and application, and belongs to the technical field of aquatic compound feed. Background technique [0002] bream ( Megalobrama amblycephala ), belonging to the class Teleost, Cyprinidae, Cyprinidae, Subfamily Bream, and genus Bream. It is one of the main freshwater aquaculture species in my country. In 2013, the aquaculture output of roundhead bream has exceeded 700,000 tons. In recent years, with the increase of breeding density, diseases have occurred frequently, and the breeding industry of bream has brought huge economic losses. In order to prevent and control pathogenic bacteria, antibiotics and antibacterial drugs have been used in large quantities, resulting in drug residues, enhanced drug resistance, and causing animal diseases. A series of adverse consequences such as decreased immunity, some antibiotics or antibacterial...

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Problems solved by technology

[0010] Some recent patents: Yu Yunzhen et al. (2010) applied for a patent (201010162861.1) for a compound Chinese herbal medicine preparation for fish and its preparation method; Zhang Zhongzhong (2011) applied for a patent (201110201424.0) for a compound Chinese herbal medicine immune enhancer for fish and its preparation method; Zhang Lu et al. (2011) applied for a patent (201110186183.7) for a general-purpose compound Chinese herbal medicine immune enhancer for freshwater aquaculture fish; Liu Bo et al. (2012) applied for a patent (20210573614.X) a compound Chinese herbal medicine anti-stress preparation, preparation method and its Previous patents, such as the method of use, all described the compound Chinese herbal medicine preparation for improving the immunity of fish, but there are few papers and patents on the compound Chinese herbal medicine extract for improving the immunity of pombra bream

At present, there are some applications of gallnut, rhubarb, forsythia, licorice, and astragalus in aquaculture, most of which are directly compounded or single-flavored Chinese herbal extracts in aquaculture. , Glycyrrhizae, Radix Astragali, Hedyotis diffusa, and Burdock Fructus Compatible Extraction of the main components and their use have not been reported