Suppository containing high-elasticity-modulus viscose fiber and preparation method thereof

A technology of viscose fiber and high elasticity, which is applied in the field of medicine, and can solve the problems that the expansion carrier cannot effectively expand, the drug cannot effectively reach the focus, and is not conducive to the treatment of gynecological diseases, so as to improve compliance, effectively expand, and the preparation method is simple and easy to operate Effect

Active Publication Date: 2015-02-04
哈尔滨田美药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In existing suppositories, the expansion carrier is a general material with low water absorption, small elastic modulus, and small expansion coefficient. The expansion carrier cannot effectively expand, so that the drug cannot effectively reach the lesion, prolonging the treatment time and reducing the quality of treatment, which is not conducive to treatment. The treatment of gynecological diseases, so there is an urgent need to provide a new material suitable for the expansion carrier

Method used

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  • Suppository containing high-elasticity-modulus viscose fiber and preparation method thereof
  • Suppository containing high-elasticity-modulus viscose fiber and preparation method thereof
  • Suppository containing high-elasticity-modulus viscose fiber and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] Example 1 High elastic modulus viscose fiber

[0039] High elastic modulus viscose fiber is prepared by processing raw fiber including the following parts by weight:

[0040] Cotton fiber 10 Rose fiber 5 Silk 40 Acetate fiber 8

[0041] Preparation:

[0042] a. Mix cotton fiber, rose fiber, silk, and acetate fiber to obtain composite cellulose pulp;

[0043] b. Immerse the composite cellulose pulp in a 10% NaOH solution at 52°C for 30 minutes to obtain alkali cellulose;

[0044] c. After the alkali cellulose is squeezed and pulverized by a press, it undergoes a yellowing reaction with carbon disulfide to generate cellulose xanthate, the temperature of the yellowing reaction is 25° C., and the yellowing time is 100 min;

[0045] d. Dissolve the cellulose xanthate in a 10% NaOH solution for 60 minutes to obtain a viscose solution;

[0046] e. The viscose solution is matured at 20°C for 30 min, and defoamed and filtered during the maturation process to obtain a spinning solution;

[004...

Embodiment 2

[0048] Example 2 High elastic modulus viscose fiber

[0049] High elastic modulus viscose fiber is prepared by processing raw fiber including the following parts by weight:

[0050] Cotton fiber 30 Rose fiber 25 Silk 15 Acetate fiber 3

[0051] Preparation method: According to the method of Example 1, a high elastic modulus viscose fiber was prepared.

Embodiment 3

[0052] Example 3 High elastic modulus viscose fiber

[0053] High elastic modulus viscose fiber is prepared by processing raw fiber including the following parts by weight:

[0054] Cotton fiber 20 Rose fiber 15 Silk 30 Acetate fiber 5

[0055] Carbon Fiber 2 Ethylene Butyl Acrylate 2

[0056] Preparation:

[0057] a. Blend cotton fiber, rose fiber, silk, acetate fiber, and carbon fiber to obtain composite cellulose pulp;

[0058] b. Immerse the composite cellulose pulp in a 10% NaOH solution at 52°C for 30 minutes to obtain alkali cellulose;

[0059] c. Add ethylene butyl acrylate to the alkali cellulose, mix it evenly, press and pulverize by a press, and then undergo a yellowing reaction with carbon disulfide to produce cellulose xanthate. The temperature of the yellowing reaction is 25°C, The yellowing time is 100min;

[0060] d. Dissolve the cellulose xanthate in a 10% NaOH solution for 60 minutes to obtain a viscose solution;

[0061] e. The viscose solution is matured at 20°C for 30 ...

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Abstract

The invention discloses a suppository containing a high-elasticity-modulus viscose fiber and a preparation method thereof. The high-elasticity-modulus viscose fiber is processed and prepared from cotton fiber, rose fiber, silk and acetate fiber. A suppository expanding supporter containing the high-elasticity-modulus viscose fiber is prepared from the high-elasticity-modulus viscose fiber as a raw material. The high-elasticity-modulus viscose fiber is high in water absorption rate and is high in elasticity modulus. The expanding supporter is high in expanding coefficient and can be effectively expanded, which enables medicine to arrive lesion directly, thereby achieving a good curative effect. Meanwhile, the expanding supporter has a refreshing effect, which is beneficial for enhancing patient compliance. The preparation method is easy to carry out.

Description

Technical field [0001] The invention belongs to the field of medicine, and particularly relates to a suppository containing viscose fiber with high elastic modulus and a preparation method thereof. technical background [0002] Gynecological diseases are common and frequently-occurring diseases in women. At present, the treatment of gynecological diseases generally uses vaginal suppositories containing active ingredients for the treatment of diseases. The drugs can directly reach the lesions and have good curative effects and overcome the side effects of oral preparations. In the existing suppositories, the swelling carrier is a general material with low water absorption, small elastic modulus, and small expansion coefficient. The swelling carrier cannot effectively expand, resulting in the inability of the drug to reach the lesion effectively, prolonging the treatment time, reducing the treatment quality, and not conducive to For the treatment of gynecological diseases, there is...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/02A61K47/46A61K47/04A61K47/14A61K47/32A61K47/36A61K47/10A61K47/34A61K47/18A61K47/44A61K45/00A61P15/00
Inventor 邱学良邱明世
Owner 哈尔滨田美药业股份有限公司
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