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A kind of rhubarb total anthraquinone capsule composition

A technology of rhubarb total anthraquinones and anthraquinone capsules, which can be used in capsule delivery, drug combination, plant raw materials, etc., and can solve problems such as inability to use for a long time, affecting curative effect, skin allergies, etc.

Active Publication Date: 2016-08-24
江西百神昌诺药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0020] 1. The weak and elderly should be used with caution. Those with a strong physique will stop when they get sick. Do not use it for a long time.
[0021] 2. Those who have skin allergies after taking the medicine should stop using it
[0023] 4. Stop using when you have a cold
[0028] The rhubarb total anthraquinone capsules prepared by the prior art have a shelf life of only 18 months, which is far lower than the 2-3 year shelf life of common Chinese medicine preparations, so it is necessary to study New Rhubarb Total Anthraquinone Capsules for Improved Shelf Life
In addition, the existing rhubarb total anthraquinone capsules often cause gastrointestinal irritation during use, so that patients often interrupt treatment, which affects the curative effect

Method used

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  • A kind of rhubarb total anthraquinone capsule composition
  • A kind of rhubarb total anthraquinone capsule composition
  • A kind of rhubarb total anthraquinone capsule composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0135] Each 1000 capsules is prepared from the content components in the following weight ratios:

[0136]

[0137] The preparation method of the rhubarb total anthraquinone capsule of invention is as follows:

[0138] 1) Rhubarb total anthraquinones, microcrystalline cellulose, aluminum hydroxide xerogel, and sodium bicarbonate are mixed evenly;

[0139] 2) Povidone is dissolved in 95% (v / v) ethanol, prepared to contain 10% povidone solution (10 parts by weight of povidone are dissolved in 95% ethanol to obtain 100 parts by volume of povidone Ketone ethanol solution);

[0140] 3) Add 10% povidone solution into the above mixture and stir evenly, make soft material, sieve through 18 meshes to make granules, dry, add magnesium stearate after granules are dry, mix evenly, pack 1000 capsules.

Embodiment 2

[0142] The recipe is

[0143] Each 1000 capsules is prepared from the content components in the following weight ratios:

[0144]

[0145] The preparation method is as follows:

[0146] 1) Rhubarb total anthraquinones, microcrystalline cellulose, aluminum hydroxide xerogel, and sodium bicarbonate are mixed evenly;

[0147] 2) Povidone is dissolved in 95% (v / v) ethanol, prepared to contain 10% povidone solution (10 parts by weight of povidone are dissolved in 95% ethanol to obtain 100 parts by volume of povidone Ketone ethanol solution);

[0148] 3) Add 10% povidone solution into the above mixture and stir evenly, make soft material, sieve through 18 meshes to make granules, dry, add magnesium stearate after granules are dry, mix evenly, pack 1000 capsules.

Embodiment 3

[0150] The recipe is

[0151] Each 1000 capsules is prepared from the content components in the following weight ratios:

[0152]

[0153] The preparation method is as follows:

[0154] 1) Rhubarb total anthraquinones, microcrystalline cellulose, aluminum hydroxide xerogel, and sodium bicarbonate are mixed evenly;

[0155] 2) Povidone is dissolved in 95% (v / v) ethanol, prepared to contain 10% povidone solution (10 parts by weight of povidone are dissolved in 95% ethanol to obtain 100 parts by volume of povidone Ketone ethanol solution);

[0156] 3) Add 10% povidone solution into the above mixture and stir evenly, make soft material, sieve through 18 meshes to make granules, dry, add magnesium stearate after granules are dry, mix evenly, pack 1000 capsules.

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PUM

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Abstract

The invention relates to a rhubarb total anthraquinone capsule composition consisting of following components, by weight: 50-100g of rhubarb total anthraquinone, 140-160g of microcrystalline cellulose, 18-22g of aluminium hydroxide dry gel, 18-22g of sodium bicarbonate, 4-6g of povidone and 4-6g of magnesium stearate.

Description

Technical field: [0001] The invention relates to a traditional Chinese medicine extract preparation, in particular to a rhubarb total anthraquinone capsule preparation which uses the rhubarb total anthraquinone extracted from the traditional Chinese medicine rhubarb as an active ingredient and a preparation method thereof. Background technique: [0002] Rhubarb is one of the commonly used traditional Chinese medicines. It is the dried root and rhizome of rhubarb palmatum, rhubarb tangutica or medicinal rhubarb, which is a perennial herb of Polygonaceae. [0003] Rhubarb is bitter in taste, cold in nature, and has the effects of purging and attacking, clearing heat and purging fire, cooling blood and detoxifying, removing blood stasis and stimulating menstruation. Modern chemical research proves that the main chemical components of rhubarb are anthraquinone compounds; the extraction and separation methods of rhubarb active ingredients mainly include: decoction method (water e...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/708A61K9/48A61K47/02A61P1/16A61P31/20
CPCA61K9/4866A61K36/708A61K2236/333A61K2236/51A61K2236/53
Inventor 付诚付志高
Owner 江西百神昌诺药业有限公司