68 results about "Anthraquinone Compounds" patented technology

The invention provides a hydrophilic modified HDPE composition and application thereof, and relates to the technical field of composite materials. The hydrophilic modified HDPE composition is prepared from the following raw material components in parts by weight: 100 parts of HDPE and 1 to 10 parts of a hydrophilic anthraquinone compound. Preferably, the raw material component also can comprise 0.1-2 parts of a carbon-based material. The hydrophilic anthraquinone compound is obtained by reacting an anthraquinone compound with a diisocyanate compound and then reacting with a hydrophilic compound. According to the hydrophilic modified HDPE composition disclosed by the invention, the hydrophilicity of HDPE is improved, and an anthraquinone structure is introduced, so that the denitrification effect on nitrogen-containing sewage can be improved.

The invention provides a polyurethane composite material and application thereof, and relates to the technical field of polyurethane materials. The polyurethane composite material consists of a component A and a component B, the component A comprises the following raw material components in parts by weight: 100 parts of polymer dihydric alcohol, 1-8 parts of a chain extender, 1-3 parts of a catalyst, 0-5 parts of a cross-linking agent, 0.1-2 parts of a carbon-based material, 1-10 parts of an anthraquinone compound and 0.5-2 parts of water; and the component B is an isocyanate curing agent and comprises a prepolymer with a plurality of ester bonds and urea bonds. The polyurethane composite material disclosed by the invention has relatively high mechanical strength, wear resistance and the like, and is suitable for treating nitrogen-containing sewage.

The invention discloses an aloe extract-containing antibacterial, anti-inflammatory, anti-aging and moisturizing composition capable of promoting wound repair and application of the aloe extract-containing antibacterial, anti-inflammatory, anti-aging and moisturizing composition. The composition provided by the invention is obtained by compounding the active ingredients such as the aloe extract, the coptis chinensis extract, the centella asiatica extract, the honeysuckle flower extract and the carboxymethyl chitosan, all the ingredients synergistically play the roles of resisting bacteria, diminishing inflammation, resisting aging, promoting wound repair and moisturizing, and the composition has a remarkable effect. Wherein the aloe extract is prepared by adopting a specific deep eutectic solvent (DES), so that the content of anthraquinone compounds in the aloe extract can be increased, and the effects of bacteriostasis, sterilization, inflammation diminishing, detoxification, moisturizing and wound healing promotion of aloe can be better exerted. Specific extract components and the aloe extract are compounded, so that the effect of the aloe extract can be enhanced, the adopted components are natural, mild, safe and low in irritation, and a basis is provided for preparing more medicine products which are antibacterial, anti-inflammatory, anti-aging, moisturizing and capable of promoting wound repair.

The invention provides an olefin polymer composition and application thereof, and relates to the technical field of composite materials. The olefin polymer composition is prepared from the following raw material components in parts by weight: 100 parts of an olefin polymer, 0.5 to 5 parts of an anthraquinone compound and 1 to 5 parts of aspartic ester resin, the structure of the aspartic ester resin contains C8-C24 alkylene and a polyethylene glycol chain segment. The olefin polymer composition has good hydrophilicity, and the treatment effect of the olefin polymer composition on nitrogen-containing sewage can be improved.

The invention discloses a method for predicting liquid chromatography retention time of traditional Chinese medicine active ingredients. The method comprises the following steps: detecting retention time of flavonoid compounds or anthraquinone compounds under different chromatographic conditions through a reverse high performance liquid chromatograph; performing structure optimization on the flavonoid compound or the anthraquinone compound; performing molecular descriptor calculation on the optimized compound structure to obtain a molecular descriptor data set; performing genetic algorithm screening on the molecular descriptor data set to obtain characteristic molecular descriptors; combining the characteristic molecule descriptors with the different chromatographic conditions into a complete data set; the complete data set serves as an input variable, retention time serves as an output variable, and a gradient elevator GB algorithm or a random forest method RF is adopted for modeling to obtain a QSRR model; and predicting the retention time of flavonoid or anthraquinone compounds under different chromatographic conditions by using the constructed QSRR model.

The invention discloses an anthraquinone compound with anti-MTV activity and a preparation method and application thereof.The anthraquinone compound with the anti-MTV activity is prepared from stems and leaves of desmodium caudatum through the steps of pretreatment, extract extraction, silica gel column chromatography and separation and purification, the molecular formula of the anthraquinone compound with the anti-MTV activity is C18H17O7, and the structural formula of the anthraquinone compound with the anti-MTV activity is shown in the description. The preparation method comprises the following steps: 1, 6-dihydroxy-2, 7, 8-trimethoxy-3-methyl anthracene-9, 10-diketone is used as a raw material, and is named as 1, 6-dihydroxy-2, 7, 8-trimethoxy-3-methyl According to the invention, the English name is 1, 6-dihydroxy-2, 7, 8-trimesoxy-3-methylanthracene-9, 10-dione, and the English name is 1, 6-dihydroxy-2, 7, 8-trimesoxy-3-methylanthracene-9, 10-dione. The present invention has the following structure. Activity tests show that the compound has a certain inhibition effect on MTV. The novel compound disclosed by the invention is novel in structure, has certain anti-MTV activity, can be used as an anti-MTV lead compound, and can be used for research and development of anti-MTV prevention and treatment drugs.

The invention relates to application of anthraquinone compounds and pharmaceutically acceptable salts thereof in preparation of drugs for treating anemia, the anthraquinone compounds have a structure as shown in formula I. In the formula I, R1-R5 are independently selected from hydrogen, hydroxyl, unsubstituted or hydroxyl-substituted C1-C6 linear or branched alkyl, C1-C6 alkoxy, C1-C6 acyl or-(CH2) n1O (CH2) n2CH3, n1 is selected from 1, 2 or 3, and n2 is selected from 0, 1, 2 or 3. The anthraquinone compound provided by the invention can significantly up-regulate the transcriptional levels of HAMP, EPO and HBG1 genes, has a good treatment effect on thalassemia and beta-sickle anemia, has no significant influence on cell viability and mouse weight, and has medication safety.

The present invention relates to the process for the preparation of topical formulations of anthraquinone compound. The present invention specifically relates to the process for the preparation of topical formulations of Rhein or Diacerein in the form of ointment, cream, gel and transferosomal gel. The present invention more specifically relates to the process for the preparation of topical formulations of Rhein or Diacerein in the form of ointment, cream, gel comprising the steps of heating, adding, stirring, dissolving and mixing. The present invention also relates to the process for the preparation of topical formulations of Rhein or Diacerein in the form of transferosomal gel comprising the steps of thin film formation, hydration of thin film and transferosomal gel formation. The present invention also relates to the process for the preparation of topical formulations of Rhein or Diacerein in the form of transferosomal gel comprising the steps of dissolving, adding and mixing.

Provided are: a mutant glycosyltransferase which has 80% or more sequence identity with the amino acid sequence represented by SEQ ID NO: 1 and is capable of forming an anthraquinone C glycoside from an anthraquinone compound and a monosaccharide donor; a method for producing the mutant glycosyltransferase; a nucleic acid; a vector;

The application provides a polyurethane composite material and application thereof, and relates to the technical field of polyurethane materials. The polyurethane composite material is composed of component A and component B. Raw material components of component A include: 100 parts of polymeric diol, 1-8 parts of chain extender, 1-3 parts of catalyst, 0-5 parts of crosslinking agent, 0.1-2 parts of carbon-based material, 1-10 parts of anthraquinone compound and 0.5-2 parts of water. Component B is an isocyanate curing agent, and contains a prepolymer with multiple ester bonds and urea bonds. The polyurethane composite material has high mechanical strength and wear resistance and the like, and is suitable for treatment of nitrogen-containing sewage.

Provided is a novel anthraquinone compound. The anthraquinone compound is represented by formula (1).

The invention provides a composite material composition, and relates to the technical field of composite materials. The composite material composition comprises the following raw material components in parts by weight: 100 parts of polyolefin, 1-10 parts of an anthraquinone compound and 0.1-2 parts of a carbon-based material, the carbon-based material is subjected to surface treatment by adopting polyether modified polysiloxane. Preferably, the polyether modified polysiloxane contains an active group which can react with the anthraquinone compound at 100 DEG C. The composite material disclosed by the invention combines the characteristics of the anthraquinone compound, the carbon-based material and the polyether modified polysiloxane, synergistically exerts effects, and has a relatively good denitrification effect on nitrogen-containing sewage.

The present invention discloses an anthraquinone compound having anti-tobacco mosaic virus activity, a preparation method and an application thereof. The molecular formula of the compound is: C 19 H 14 O4, the compound is named: 2',5-dimethyl-6-hydroxymethylanthracene[2,3- b ]furan-9,10-dione, English name: 6-hydroxymethyl-2',5-dimethylanthra[2,3- b Furan-9,10-dione has the following structure: This compound was isolated for the first time from the Dai medicinal plant, the genus Ligusticum chuanxiong. It was identified as an anthraquinone compound by nuclear magnetic resonance and mass spectrometry, and its specific structure was characterized. This anthraquinone compound exhibits excellent anti-tobacco mosaic virus activity: in experiments against tobacco mosaic virus, its relative inhibition rate reached 43.2%, significantly higher than the relative inhibition rate of the reference substance, ningnanmycin (32.4%). This compound has promising application prospects in the preparation of anti-tobacco mosaic virus drugs and can serve as a lead compound for such drugs.

Provided is an anthraquinone compound of formula (1). (R1 and R4 each represent -H, a C1-12 linear or branched alkyl group, a C1-12 linear or branched alkoxy group, a halogen atom, -CO2R8, -OCOR8, -COR8, -CONR9R10, -NR11R12, -CN, or -CF3. R2, R3, R5, and R6 each represent –H, a C1-4 linear or branched alkyl group, a C1-4 linear or branched alkoxy group, a halogen atom, -CO2R8, -OCOR8, -COR8, -CONR9R10, -NR11R12, -CN, or -CF3. R7 represents a C1-12 linear or branched alkyl group, a C1-12 linear or branched alkoxy group, or a substituent represented by formula (a) (wherein, R13 represents –H or a C1-8 linear alkyl group). R8 represents a C1-8 linear or branched alkyl group or the like, and R9 to R12 each represent a C1-8 linear or branched alkyl group.)

The invention relates to the technical field of batteries, in particular to a battery, a battery liquid leakage detection method and a power utilization device. The battery provided by the invention comprises an electrolyte and a shell for packaging the electrolyte, a first reagent is added into the electrolyte, the first reagent comprises a boron compound, the outer surface of the shell is provided with the first reagent, the first reagent comprises an anthraquinone compound, and the chemical general formula of the anthraquinone compound is shown as a formula I in the specification. Based on the fact that an anthraquinone compound can be in contact with a boron compound in an electrolyte and is subjected to a coupling reaction with the boron compound, o-diphenolic hydroxyl of the anthraquinone compound is complexed with boron to generate a fluorescent complex, if liquid leakage exists in the battery, a fluorescent color development peak of the fluorescent complex can be detected through photosensitive detection equipment, and the fluorescent color development peak of the fluorescent complex can be detected through detection equipment. Therefore, whether electrolyte leakage exists or not can be conveniently and sensitively detected.

The application provides a hydrophilic modified HDPE composition and application thereof, and relates to the technical field of composite materials.The hydrophilic modified HDPE composition contains, in terms of weight parts, 100 parts of HDPE and 1-10 parts of a hydrophilic anthraquinone compound.The raw material components can further contain 0.1-2 carbon-based materials.The hydrophilic anthraquinone compound is obtained by reacting an anthraquinone compound and a diisocyanate compound and then reacting with a hydrophilic compound.The hydrophilic modified HDPE composition improves the hydrophilicity of HDPE, and introduces an anthraquinone structure, so that the denitrification effect on nitrogen-containing sewage can be improved.

The present invention is an anthraquinone compound represented by formula (1) (in the formula, R1 represents a hydrogen atom, a straight chain or branched chain alkyl group having a carbon count of 1-12, or a straight chain or branched chain alkoxy group having a carbon count of 1-12. R2 represents a hydrogen atom, a straight chain or branched chain alkyl group having a carbon count of 1-8, or a straight chain or branched chain alkoxy group having a carbon count of 1-8). R2 may be a straight chain or branched chain alkyl group having a carbon count of 1-8. R1 may be a straight chain or branched chain alkoxy group having a carbon count of 1-8, or may be a straight chain or branched chain alkyl group having a carbon count of 1-4. The present invention also relates to a dimming liquid crystal composition containing this anthraquinone compound and a liquid crystal material. The present invention also relates to a dimming element obtained by sandwiching the dimming liquid crystal composition or a photocured product thereof between a pair of substrates disposed facing each other, at least one among which is a transparent substrate having a transparent electrode.

The application relates to the technical field of wet electronic chemicals, and discloses a production method of high-purity activated carbon for preparing electronic-grade hydrogen peroxide, and the specific preparation process steps are as follows: step one: high-quality coal liquefied pitch is used as an extraction agent, 1000 kg of high-quality coal liquefied pitch is added into 2000 kg of refined naphthalene, 150 kg of anhydrous aluminum chloride is further added, and stirring reaction is carried out under oil bath at 180 DEG C for 120 min; step two: solid-liquid separation is realized by using a horizontal solid-liquid centrifuge, and the solid phase is discarded, more than 90% of the anhydrous aluminum chloride is removed, the ash content of the activated carbon is less than 0.3%, and the quality is stable; in the primary treatment of preparing the electronic-grade hydrogen peroxide, more than 99% of organic impurities, more than 95% of inorganic impurities and the like in industrial hydrogen peroxide can be removed, the organic impurities are aromatic hydrocarbons, octanol, tri-octyl phosphate, anthraquinone compounds and phenols, the inorganic impurities are calcium, sodium, potassium, iron, aluminum and silicon, the adsorption capacity of the activated carbon does not obviously decrease after being regenerated for 5 times, and the use cost of customers is greatly reduced.

Provided are a mutant glycosyltransferase having 80% or more sequence identity with an amino acid sequence set forth in SEQ ID NO: 1, in which the mutant glycosyltransferase is capable of forming an anthraquinone C-glycoside from an anthraquinone compound and a monosaccharide donor; a method for producing the same; a nucleic acid; a vector; a host cell; a composition; and a method for producing an anthraquinone C-glycoside.

The invention discloses an anthraquinone compound as well as a preparation method and application thereof in resisting prostatic cancer. The structure of the anthraquinone compound 1 is shown as a formula (I). According to the present invention, the solid fermentation extract product of Aspergillus versicola SCSIO 41323 is subjected to separation and purification so as to obtain the compound Nidurufin (1), wherein the compound Nidurufin (1) is obtained from the solid fermentation extract product of Aspergillus versicola SCSIO 41323; prostate cancer cell activity evaluation finds that the compound 1 can significantly inhibit the activity of prostate cancer cells and inhibit cell proliferation, protein expression of AR, KLK3, MBOAT2 and the like can be significantly inhibited by increasing ROS activity and inducing ferroptosis of prostate cancer cells, and the Nidurfin (1) can inhibit growth of prostate cancer cells in vitro and in vivo, and can inhibit growth of prostate cancer cells in vitro and in vivo. The method is of great significance to development and utilization of deep sea abyssal and other extreme environment source microbial resources.

The present application relates to a kind of methyltransferase that can catalyze anthraquinone compound methylation, amino acid sequence is as shown in SEQ ID NO:2, also provide the application of this methyltransferase in the production of emodin-3-methyl ether and other methylated anthraquinone compounds.The present application digs a new methyltransferase, which can methylate anthraquinone compound, and can convert emodin into emodin-3-methyl ether.The present application constructs the engineering bacteria that can produce emodin-3-methyl ether using the coding gene of the enzyme, widens the methyltransferase library that can be used for emodin methylation, provides new way for emodin-3-methyl ether cell factory construction.

This invention discloses a nitrogen-containing heterocyclic anthraquinone compound with anti-tobacco mosaic virus activity, its preparation method, and its applications. The molecular formula of the compound is: C 22 H 19 NO4, the compound is named: 5-methyl-3,6-dimethoxy-2-(3'-methyl-1'-) H 3,6-dimethoxy-5-methyl-2-(3'-methyl-1'-yl)anthracene-9,10-dione, also known as pyrrole-2'-yl)anthracene-9,10-dione. H The compound of this invention, denoted as -pyrrol-2'-yl)anthracene-9,10-dione, has the following structure: This compound was first isolated from the Dai medicinal herb *Cassia tora*. This nitrogen-containing heterocyclic anthraquinone compound exhibits excellent anti-tobacco mosaic virus (Tobacco Mosaic Virus) activity: in experiments against Tobacco Mosaic Virus, its relative inhibition rate reached 56.2%, significantly higher than the relative inhibition rate of the control compound ningnanmycin (32.4%). The compound of this invention has a stable structure and good activity, showing promising application prospects in the preparation of anti-Tobacco Mosaic Virus drugs and can serve as a lead compound for anti-Tobacco Mosaic Virus drugs.

The present application belongs to the technical field of mobile bed biological membrane reactor, and discloses a preparation method of MBBR filler and the MBBR filler.The preparation method of the MBBR filler disclosed by the present application comprises the following steps: S1, mixing polyolefin, chitosan and maleic anhydride grafted polyolefin, melting, extruding, shaping, and obtaining first filler; S2, dispersing the first filler in step S1 into an organic solvent, adding an anthraquinone compound containing anhydride, reacting, filtering, washing, and drying to obtain the MBBR filler.The MBBR filler obtained by the preparation method provided by the present application has good mechanical strength, hydrophilicity, biocompatibility and biofilm performance, and has good application prospect.

To provide an ink having excellent storage stability and high light fastness.SOLUTION: Provided is an ink including a medium and carrier particles dyed with an anthraquinone compound as a cyan colorant, a monoazo compound as a magenta colorant, and a pyrazoline compound as a yellow colorant.SELECTED DRAWING: None

The purpose of the present invention is to provide a novel anthraquinone compound, and to provide: a dichroic dye constituted of the novel anthraquinone compound; a liquid crystal composition which contains the dichroic dye; and preferably a dimming element having excellent contrast and light resistance and containing said composition.　The present invention discloses an anthraquinone compound represented by formula A below (wherein R1 represents a C3-16 branched alkyl group, and R2 represents a hydrogen atom, a C1-8 straight-chain or branched alkyl group, or a C1-8 straight-chain or branched alkoxy group). In addition, the present invention discloses a liquid crystal composition including the anthraquinone compound and a liquid crystal material, and a dimming element containing said composition.

The present invention is an anthraquinone compound represented by formula (1) (in the formula, R1 represents a hydrogen atom, a straight chain or branched chain alkyl group having a carbon count of 1-12, or a straight chain or branched chain alkoxy group having a carbon count of 1-12. R2 represents a hydrogen atom, a straight chain or branched chain alkyl group having a carbon count of 1-8, or a straight chain or branched chain alkoxy group having a carbon count of 1-8). R2 may be a straight chain or branched chain alkyl group having a carbon count of 1-8. R1 may be a straight chain or branched chain alkoxy group having a carbon count of 1-8, or may be a straight chain or branched chain alkyl group having a carbon count of 1-4. The present invention also relates to a dimming liquid crystal composition containing this anthraquinone compound and a liquid crystal material. The present invention also relates to a dimming element obtained by sandwiching the dimming liquid crystal composition or a photocured product thereof between a pair of substrates disposed facing each other, at least one among which is a transparent substrate having a transparent electrode.

The invention relates to the technical field of microbial drugs and anti-infection drugs, in particular to dianthraquinone compounds, a preparation method and application thereof.The dianthraquinone compounds dothideomin A and derivatives dothideomin C and dothideomin D of the dianthraquinone compounds dothideomin A have good in-vitro bacteriostasis and sterilization effects on MRSA and can remarkably inhibit growth of the MRSA, the minimum inhibitory concentration is 0.8-1.3 mu g / mL, dothideomin A has a unique anti-MRSA action mechanism, and dothideomin D has a unique anti-MRSA action mechanism and can remarkably inhibit growth of the MRSA. The compound has good safety to red blood cells and mammalian cells, and drug resistance of MRSA is not easy to generate. The invention provides the inhibition effect of the dothimine A and the derivative thereof on methicillin-resistant staphylococcus aureus, and the dothimine A and the derivative thereof have wide application value in the fields of medicines and the like.

The invention belongs to the technical field of biological medicine, relates to application of rhubarb free anthraquinone in depolymerization of ASC speck and treatment of related diseases, and particularly relates to novel application of rhubarb anthraquinone compounds in targeted depolymerization of inflammasome core signal complex ASC speck. According to the method for depolymerizing the ASC speck, the ASC speck can be effectively removed, and the method can be further applied to diseases caused by ASC speck accumulation, so that pathological injuries caused by the ASC speck are reduced.

The invention discloses a tetrahydroanthraquinone compound as well as a preparation method and application thereof, the tetrahydroanthraquinone compound is a compound as shown in a formula I, a stereoisomer or pharmaceutically acceptable salt of the tetrahydroanthraquinone compound, and the compound is an LIC1 inhibitor, can remarkably inhibit the progress of non-small cell lung cancer, and can be used for preparing a medicine for treating non-small cell lung cancer. Especially, the compound 18e has strong therapeutic activity in both cellular level and animal level. The invention provides a candidate drug for treating non-small cell lung cancer.